Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell division and gliomagenesis

Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells

(2017) Robert Beattie et al.   NEURON

NG2 Proteoglycan Enhances Brain Tumor Progression by Promoting Beta-1 Integrin Activation in both Cis and Trans Orientations

(2017) William B. Stallcup   Cancers

The oligodendrocyte-specific antibody ‘CC1’ binds Quaking 7

(2016) Jenea M. Bin et al.   JOURNAL OF NEUROCHEMISTRY

The phospholipid flippase ATP9A is required for the recycling pathway from the endosomes to the plasma membrane

(2016) Yoshiki Tanaka et al.   MOLECULAR BIOLOGY OF THE CELL

Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAFV600E targeted inhibition in a novel syngeneic murine glioma model

(2016) Stefan Grossauer et al.   Oncotarget

Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells

(2015) R. G. Lerner et al.   CANCER RESEARCH

Regulation of Notch signaling and endocytosis by the Lgl neoplastic tumor suppressor

(2015) Marta Portela et al.   CELL CYCLE

NG2-glia and their functions in the central nervous system

(2015) L. Dimou et al.   GLIA

Fast clonal expansion and limited neural stem cell self-renewal in the adult subependymal zone

(2015) Filippo Calzolari et al.   NATURE NEUROSCIENCE

Glia Disease and Repair—Remyelination

(2015) Robin J.M. Franklin et al.   Cold Spring Harbor Perspectives in Biology

Stonin1 mediates endocytosis of the proteoglycan NG2 and regulates focal adhesion dynamics and cell motility

(2015) Fabian Feutlinske et al.   Nature Communications

PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1

(2015) Alexander Gont et al.   Oncotarget

Inhibition of glioblastoma malignancy by Lgl1

(2015) Alexander Gont et al.   Oncotarget

Most Human Non-GCIMP Glioblastoma Subtypes Evolve from a Common Proneural-like Precursor Glioma

(2014) Tatsuya Ozawa et al.   CANCER CELL

Lgl Regulates Notch Signaling via Endocytosis, Independently of the Apical aPKC-Par6-Baz Polarity Complex

(2014) Linda M. Parsons et al.   CURRENT BIOLOGY

The Scribble module regulates retromer-dependent endocytic trafficking during epithelial polarization

(2014) Geert de Vreede et al.   DEVELOPMENT

Early phenotypic asymmetry of sister oligodendrocyte progenitor cells after mitosis and its modulation by aging and extrinsic factors

(2014) Enrica Boda et al.   GLIA

NG2 cells (polydendrocytes): Listeners to the neural network with diverse properties

(2014) Robert A. Hill et al.   GLIA

Oncogenic Signaling Is Dominant to Cell of Origin and Dictates Astrocytic or Oligodendroglial Tumor Development from Oligodendrocyte Precursor Cells

(2014) N. Lindberg et al.   JOURNAL OF NEUROSCIENCE

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Modulation of oligodendrocyte generation during a critical temporal window after NG2 cell division

(2014) Robert A Hill et al.   NATURE NEUROSCIENCE

Transformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation process

(2014) Rui Pedro Galvao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGFβ Lengthens the G1 Phase of Stem Cells in Aged Mouse Brain

(2014) Mathieu Daynac et al.   STEM CELLS

Nonmuscle Myosin II Is a Critical Regulator of Clathrin-Mediated Endocytosis

(2014) Indra Chandrasekar et al.   TRAFFIC

Asymmetric cell division of stem and progenitor cells during homeostasis and cancer

(2013) Sandra Gómez-López et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Rho GTPase Rac1 is required for recycling endosome-mediated secretion of TNF in macrophages

(2013) Amanda C Stanley et al.   IMMUNOLOGY AND CELL BIOLOGY

Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain

(2013) Victoria A. Rafalski et al.   NATURE CELL BIOLOGY

Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain

(2013) Ethan G Hughes et al.   NATURE NEUROSCIENCE

Oligodendrocyte Dynamics in the Healthy Adult CNS: Evidence for Myelin Remodeling

(2013) Kaylene M. Young et al.   NEURON

Quiescent neural stem cells exit dormancy upon alteration of GABAAR signaling following radiation damage

(2013) Mathieu Daynac et al.   Stem Cell Research

Coordinated control of oligodendrocyte development by extrinsic and intrinsic signaling cues

(2013) Li He et al.   Neuroscience Bulletin

Clathrin-Mediated Endocytosis Persists during Unperturbed Mitosis

(2013) Silvia K. Tacheva-Grigorova et al.   Cell Reports

Myosin II is a negative regulator of oligodendrocyte morphological differentiation

(2012) Haibo Wang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The tumor suppressor Lgl1 regulates NMII-A cellular distribution and focal adhesion morphology to optimize cell migration

(2012) Inbal Dahan et al.   MOLECULAR BIOLOGY OF THE CELL

Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy

(2012) E. Huillard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Asymmetry-Defective Oligodendrocyte Progenitors Are Glioma Precursors

(2011) Sista Sugiarto et al.   CANCER CELL

Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma

(2011) Chong Liu et al.   CELL

Age-dependent fate and lineage restriction of single NG2 cells

(2011) X. Zhu et al.   DEVELOPMENT

Lgl1 Activation of Rab10 Promotes Axonal Membrane Trafficking Underlying Neuronal Polarization

(2011) Tong Wang et al.   DEVELOPMENTAL CELL

Synapses between NG2 glia and neurons

(2011) Dominik Sakry et al.   JOURNAL OF ANATOMY

Brain-derived Neurotrophic Factor (BDNF) Induces Polarized Signaling of Small GTPase (Rac1) Protein at the Onset of Schwann Cell Myelination through Partitioning-defective 3 (Par3) Protein

(2011) Chhavy Tep et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian Llgl2 Is Necessary for Proper Branching Morphogenesis during Placental Development

(2011) S. Sripathy et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Non-Stem Cell Origin for Oligodendroglioma

(2010) Anders I. Persson et al.   CANCER CELL

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

CNS-Resident Glial Progenitor/Stem Cells Produce Schwann Cells as well as Oligodendrocytes during Repair of CNS Demyelination

(2010) Malgorzata Zawadzka et al.   Cell Stem Cell

PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas

(2010) T. Ozawa et al.   GENES & DEVELOPMENT

NG2+ CNS Glial Progenitors Remain Committed to the Oligodendrocyte Lineage in Postnatal Life and following Neurodegeneration

(2010) Shin H. Kang et al.   NEURON

Polarity and endocytosis: reciprocal regulation

(2010) Jessica M. Shivas et al.   TRENDS IN CELL BIOLOGY

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

The NG2 proteoglycan promotes oligodendrocyte progenitor proliferation and developmental myelination

(2009) K. Kucharova et al.   NEUROSCIENCE

Oligodendrocyte progenitor cells can act as cell of origin for experimental glioma

(2009) N Lindberg et al.   ONCOGENE

Remyelination in the CNS: from biology to therapy

(2008) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE

Dividing glial cells maintain differentiated properties including complex morphology and functional synapses

(2008) W.-P. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA