Quantitative characterization of protein–protein complexes involved in base excision DNA repair

A Quantitative Assay Reveals Ligand Specificity of the DNA Scaffold Repair Protein XRCC1 and Efficient Disassembly of Complexes of XRCC1 and the Poly(ADP-ribose) Polymerase 1 by Poly(ADP-ribose) Glycohydrolase

(2014) In-Kwon Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PARP1–TDP1 coupling for the repair of topoisomerase I–induced DNA damage

(2014) Benu Brata Das et al.   NUCLEIC ACIDS RESEARCH

HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β

(2014) Qingming Fang et al.   Nature Communications

Interaction of PARP-2 with DNA structures mimicking DNA repair intermediates and consequences on activity of base excision repair proteins

(2013) Mikhail M. Kutuzov et al.   BIOCHIMIE

Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses

(2013) Julie K. Horton et al.   DNA REPAIR

The mechanism of human tyrosyl-DNA phosphodiesterase 1 in the cleavage of AP site and its synthetic analogs

(2013) Natalia A. Lebedeva et al.   DNA REPAIR

Clustered DNA Lesions Containing 5-Formyluracil and AP Site: Repair via the BER System

(2013) Ekaterina A. Belousova et al.   PLoS One

Tyrosyl-DNA Phosphodiesterase as a Target for Anticancer Therapy

(2012) Thomas Dexheimer et al.   Anti-Cancer Agents in Medicinal Chemistry

The region of XRCC1 which harbours the three most common nonsynonymous polymorphic variants, is essential for the scaffolding function of XRCC1

(2012) Audun Hanssen-Bauer et al.   DNA REPAIR

Pol β associated complex and base excision repair factors in mouse fibroblasts

(2012) Rajendra Prasad et al.   NUCLEIC ACIDS RESEARCH

XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage

(2011) Audun Hanssen-Bauer et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

A review of recent experiments on step-to-step “hand-off” of the DNA intermediates in mammalian base excision repair pathways

(2011) R. Prasad et al.   MOLECULAR BIOLOGY

Fluorescence strategies for high-throughput quantification of protein interactions

(2011) Aaron R. Hieb et al.   NUCLEIC ACIDS RESEARCH

Overview of Base Excision Repair Biochemistry

(2011) Yun-Jeong Kim et al.   Current Molecular Pharmacology

TDP1 serine 81 promotes interaction with DNA ligase IIIα and facilitates cell survival following DNA damage

(2010) Shih-Chieh Chiang et al.   CELL CYCLE

Base excision repair and design of small molecule inhibitors of human DNA polymerase β

(2010) Samuel H. Wilson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase   binding affinity

(2010) M. J. Cuneo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apurinic/apyrimidinic (AP) site recognition by the 5'-dRP/AP lyase in poly(ADP-ribose) polymerase-1 (PARP-1)

(2010) S. N. Khodyreva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PK

(2009) Benu Brata Das et al.   EMBO JOURNAL

Independent mechanisms of stimulation of polynucleotide kinase/phosphatase by phosphorylated and non-phosphorylated XRCC1

(2009) M. Lu et al.   NUCLEIC ACIDS RESEARCH

Single-strand break repair and genetic disease

(2008) Keith W. Caldecott   NATURE REVIEWS GENETICS

Molecular and cellular approaches for the detection of protein-protein interactions: latest techniques and current limitations

(2008) Sylvie Lalonde et al.   PLANT JOURNAL