APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress

WD40-repeat protein WDR18 collaborates with TopBP1 to facilitate DNA damage checkpoint signaling

(2013) Shan Yan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Loss of ATM kinase activity leads to embryonic lethality in mice

(2012) Jeremy A. Daniel et al.   JOURNAL OF CELL BIOLOGY

Rules of engagement for base excision repair in chromatin

(2012) Ian D. Odell et al.   JOURNAL OF CELLULAR PHYSIOLOGY

ATP-dependent conformational dynamics underlie the functional asymmetry of the replicative helicase from a minimalist eukaryote

(2012) Artem Y. Lyubimov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Double-Strand Break End Resection and Repair Pathway Choice

(2011) Lorraine S. Symington et al.   Annual Review of Genetics

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

How a DNA Polymerase Clamp Loader Opens a Sliding Clamp

(2011) B. A. Kelch et al.   SCIENCE

9-1-1: PCNA's specialized cousin

(2011) Christian S. Eichinger et al.   TRENDS IN BIOCHEMICAL SCIENCES

Continued primer synthesis at stalled replication forks contributes to checkpoint activation

(2010) Christopher Van et al.   JOURNAL OF CELL BIOLOGY

Exo1 Competes with Repair Synthesis, Converts NER Intermediates to Long ssDNA Gaps, and Promotes Checkpoint Activation

(2010) Michele Giannattasio et al.   MOLECULAR CELL

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Maintaining genome stability at the replication fork

(2010) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of rare DNA variants in mitochondrial disorders with improved array-based sequencing

(2010) Wenyi Wang et al.   NUCLEIC ACIDS RESEARCH

Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling

(2010) J.-H. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

Motors, Switches, and Contacts in the Replisome

(2009) Samir M. Hamdan et al.   Annual Review of Biochemistry

A tale of two tails: Activation of DNA damage checkpoint kinase Mec1/ATR by the 9-1-1 clamp and by Dpb11/TopBP1

(2009) Vasundhara M. Navadgi-Patil et al.   DNA REPAIR

Reconstitution of initial steps of dsDNA break repair by the RecF pathway of E. coli

(2009) N. Handa et al.   GENES & DEVELOPMENT

TopBP1 and DNA polymerase-α directly recruit the 9-1-1 complex to stalled DNA replication forks

(2009) Shan Yan et al.   JOURNAL OF CELL BIOLOGY

Single-Stranded DNA Orchestrates an ATM-to-ATR Switch at DNA Breaks

(2009) Bunsyo Shiotani et al.   MOLECULAR CELL

Role of PCNA-dependent stimulation of 3'-phosphodiesterase and 3'-5' exonuclease activities of human Ape2 in repair of oxidative DNA damage

(2009) P. Burkovics et al.   NUCLEIC ACIDS RESEARCH

Oxidative Stress and Oxidative Damage in Carcinogenesis

(2009) James E. Klaunig et al.   TOXICOLOGIC PATHOLOGY

Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation

(2008) Amit Kulkarni et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Many Functions of APE1/Ref-1: Not Only a DNA Repair Enzyme

(2008) Gianluca Tell et al.   ANTIOXIDANTS & REDOX SIGNALING

Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells

(2008) Muralidhar L Hegde et al.   CELL RESEARCH

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY