TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14
Authors
Keywords
-
Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-04-04
DOI
10.1038/s41467-018-03499-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The deubiquitinating enzyme Usp14 allosterically inhibits multiple proteasomal activities and ubiquitin-independent proteolysis
- (2017) Hyoung Tae Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ubiquitinated proteins promote the association of proteasomes with the deubiquitinating enzyme Usp14 and the ubiquitin ligase Ube3c
- (2017) Chueh-Ling Kuo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhanced Degradation of Misfolded Proteins Promotes Tumorigenesis
- (2017) Liang Chen et al. Cell Reports
- USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites
- (2016) Byung-Hoon Lee et al. NATURE
- Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome
- (2016) Y. Shi et al. SCIENCE
- Gates, Channels, and Switches: Elements of the Proteasome Machine
- (2016) Daniel Finley et al. TRENDS IN BIOCHEMICAL SCIENCES
- MEK Guards Proteome Stability and Inhibits Tumor-Suppressive Amyloidogenesis via HSF1
- (2015) Zijian Tang et al. CELL
- Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome
- (2015) Charlene Bashore et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural characterization of the interaction of Ubp6 with the 26S proteasome
- (2015) Antje Aufderheide et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy
- (2015) Jinghui Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome
- (2015) Charlene Bashore et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A Cellular System that Degrades Misfolded Proteins and Protects against Neurodegeneration
- (2014) Lili Guo et al. MOLECULAR CELL
- The amyloid state and its association with protein misfolding diseases
- (2014) Tuomas P. J. Knowles et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Regulation of proteasome activity in health and disease
- (2013) Marion Schmidt et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The Ubiquitin Code
- (2012) David Komander et al. Annual Review of Biochemistry
- Enhancement of proteasome activity by a small-molecule inhibitor of USP14
- (2010) Byung-Hoon Lee et al. NATURE
- SUMO E3 ligase activity of TRIM proteins
- (2010) Y Chu et al. ONCOGENE
- Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome
- (2009) Daniel Finley Annual Review of Biochemistry
- Defining the Human Deubiquitinating Enzyme Interaction Landscape
- (2009) Mathew E. Sowa et al. CELL
- Ubiquitinated Proteins Activate the Proteasome by Binding to Usp14/Ubp6, which Causes 20S Gate Opening
- (2009) Andreas Peth et al. MOLECULAR CELL
- Targeting proteins for degradation
- (2009) Erin K Schrader et al. Nature Chemical Biology
- Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2)
- (2009) A Arlt et al. ONCOGENE
- Autophagy fights disease through cellular self-digestion
- (2008) Noboru Mizushima et al. NATURE
- MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
- (2008) Jürgen Cox et al. NATURE BIOTECHNOLOGY
- Adapting Proteostasis for Disease Intervention
- (2008) William E. Balch et al. SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started