USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites

Gates, Channels, and Switches: Elements of the Proteasome Machine

(2016) Daniel Finley et al.   TRENDS IN BIOCHEMICAL SCIENCES

Global Analysis of Protein Expression and Phosphorylation Levels in Nicotine-Treated Pancreatic Stellate Cells

(2015) Joao A. Paulo et al.   JOURNAL OF PROTEOME RESEARCH

Ubiquitin-specific protease 14 regulates c-Jun N-terminal kinase signaling at the neuromuscular junction

(2015) Jada H Vaden et al.   Molecular Neurodegeneration

Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome

(2015) Charlene Bashore et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural characterization of the interaction of Ubp6 with the 26S proteasome

(2015) Antje Aufderheide et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substrate degradation by the proteasome: A single-molecule kinetic analysis

(2015) Y. Lu et al.   SCIENCE

Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome

(2015) Charlene Bashore et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ubiquitin-specific protease 14 modulates degradation of cellular prion protein

(2015) Takujiro Homma et al.   Scientific Reports

Disassembly of Lys11and Mixed Linkage Polyubiquitin Conjugates Provides Insights into Function of Proteasomal Deubiquitinases Rpn11 and Ubp6

(2014) Wissam Mansour et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Rpn11–Rpn8 dimer reveals mechanisms of substrate deubiquitination during proteasomal degradation

(2014) Evan J Worden et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

(2014) G. R. Pathare et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1

(2012) Nevena V. Dimova et al.   NATURE CELL BIOLOGY

Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome

(2011) Woong Kim et al.   MOLECULAR CELL

A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression

(2010) Edward L. Huttlin et al.   CELL

Enhancement of proteasome activity by a small-molecule inhibitor of USP14

(2010) Byung-Hoon Lee et al.   NATURE

Ubiquitinated Proteins Activate the Proteasome by Binding to Usp14/Ubp6, which Causes 20S Gate Opening

(2009) Andreas Peth et al.   MOLECULAR CELL

Mechanism of Ubiquitin-Chain Formation by the Human Anaphase-Promoting Complex

(2008) Lingyan Jin et al.   CELL