FoxM1 drives ADAM17/EGFR activation loop to promote mesenchymal transition in glioblastoma

Wnt‐induced deubiquitination FoxM1 ensures nucleus β‐catenin transactivation

(2016) Yaohui Chen et al.   EMBO JOURNAL

The Epithelial-to-Mesenchymal Transition-Like Process in Glioblastoma: An Updated Systematic Review and In Silico Investigation

(2016) Isabele C. Iser et al.   MEDICINAL RESEARCH REVIEWS

AKT/GSK3β Signaling in Glioblastoma

(2016) Ewelina Majewska et al.   NEUROCHEMICAL RESEARCH

Development of Resistance to EGFR-Targeted Therapy in Malignant Glioma Can Occur through EGFR-Dependent and -Independent Mechanisms

(2015) S. Klingler et al.   CANCER RESEARCH

FoxM1 Drives a Feed-Forward STAT3-Activation Signaling Loop That Promotes the Self-Renewal and Tumorigenicity of Glioblastoma Stem-like Cells

(2015) Ai-hua Gong et al.   CANCER RESEARCH

High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells

(2015) Renzhong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular subtypes, stem cells and heterogeneity: Implications for personalised therapy in glioma

(2015) Andrew Morokoff et al.   JOURNAL OF CLINICAL NEUROSCIENCE

EZH2 Protects Glioma Stem Cells from Radiation-Induced Cell Death in a MELK/FOXM1-Dependent Manner

(2015) Sung-Hak Kim et al.   Stem Cell Reports

CXCL12-induced upregulation of FOXM1 expression promotes human glioblastoma cell invasion

(2014) Shengwen Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Plumbagin induces growth inhibition of human glioma cells by downregulating the expression and activity of FOXM1

(2014) Xuejiao Liu et al.   JOURNAL OF NEURO-ONCOLOGY

RETRACTED ARTICLE: CXCR4 Signaling Induced Epithelial-Mesenchymal Transition by PI3K/AKT and ERK Pathways in Glioblastoma

(2014) Baoyu Lv et al.   MOLECULAR NEUROBIOLOGY

Dihydroartemisinin suppresses glioma proliferation and invasion via inhibition of the ADAM17 pathway

(2014) Junyan Chen et al.   NEUROLOGICAL SCIENCES

ADAM17 promotes U87 glioblastoma stem cell migration and invasion

(2013) Xiangrong Chen et al.   BRAIN RESEARCH

Sustained elevation of Snail promotes glial-mesenchymal transition after irradiation in malignant glioma

(2013) Roshan Mahabir et al.   NEURO-ONCOLOGY

ADAM17 regulates self-renewal and differentiation of U87 glioblastoma stem cells

(2013) Xiangrong Chen et al.   NEUROSCIENCE LETTERS

The Different Role of Notch1 and Notch2 in Astrocytic Gliomas

(2013) Peng Xu et al.   PLoS One

Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition

(2012) Ulf D. Kahlert et al.   CANCER LETTERS

Forkhead Box M1 Is Regulated by Heat Shock Factor 1 and Promotes Glioma Cells Survival under Heat Shock Stress

(2012) Bingbing Dai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MiR-145 reduces ADAM17 expression and inhibits in vitro migration and invasion of glioma cells

(2012) YONG LU et al.   ONCOLOGY REPORTS

FoxM1 Promotes β-Catenin Nuclear Localization and Controls Wnt Target-Gene Expression and Glioma Tumorigenesis

(2011) Nu Zhang et al.   CANCER CELL

Location, Location, Location: FoxM1 Mediates β-Catenin Nuclear Translocation and Promotes Glioma Tumorigenesis

(2011) Angela Bowman et al.   CANCER CELL

A Novel FoxM1-Caveolin Signaling Pathway Promotes Pancreatic Cancer Invasion and Metastasis

(2011) C. Huang et al.   CANCER RESEARCH

SNAI1 is Involved in the Proliferation and Migration of Glioblastoma Cells

(2011) Sung-Pil Han et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

ADAM17 promotes glioma cell malignant phenotype

(2011) Xuguang Zheng et al.   MOLECULAR CARCINOGENESIS

ADAM17: a molecular switch to control inflammation and tissue regeneration

(2011) Jürgen Scheller et al.   TRENDS IN IMMUNOLOGY

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Deregulation of FoxM1b leads to tumour metastasis

(2010) Hyun Jung Park et al.   EMBO Molecular Medicine

A transforming Src mutant increases the bioavailability of EGFR ligands via stimulation of the cell-surface metalloproteinase ADAM17

(2010) T Maretzky et al.   ONCOGENE

Transcription factor Sp1 induces ADAM17 and contributes to tumor cell invasiveness under hypoxia

(2009) Alexandra Szalad et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Sensitization of cerebral tissue in nude mice with photodynamic therapy induces ADAM17/TACE and promotes glioma cell invasion

(2008) Xuguang Zheng et al.   CANCER LETTERS