SOCE induced calcium overload regulates autophagy in acute pancreatitis via calcineurin activation

Ca 2+ signalling underlying pancreatitis

(2018) J.V. Gerasimenko et al.   CELL CALCIUM

Ca2+ tunnelling through the ER lumen as a mechanism for delivering Ca2+ entering via store-operated Ca2+ channels to specific target sites

(2017) Ole H Petersen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Calcium and ATP control multiple vital functions

(2016) Ole H. Petersen et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Autophagy Inhibition Dysregulates TBK1 Signaling and Promotes Pancreatic Inflammation

(2016) S. Yang et al.   Cancer Immunology Research

Intracellular calcium signaling regulates autophagy via calcineurin-mediated TFEB dephosphorylation

(2015) Yanju Tong et al.   Autophagy

Inhibitors of ORAI1 Prevent Cytosolic Calcium-Associated Injury of Human Pancreatic Acinar Cells and Acute Pancreatitis in 3 Mouse Models

(2015) Li Wen et al.   GASTROENTEROLOGY

Guggulsterone attenuates cerulein-induced acute pancreatitis via inhibition of ERK and JNK activation

(2015) Dong-Goo Kim et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Novel fluorescence resonance energy transfer-based reporter reveals differential calcineurin activation in neonatal and adult cardiomyocytes

(2015) Hojjat Bazzazi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Acute pancreatitis

(2015) Paul Georg Lankisch et al.   LANCET

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

(2015) Diego L. Medina et al.   NATURE CELL BIOLOGY

Store-Operated Calcium Channels

(2015) Murali Prakriya et al.   PHYSIOLOGICAL REVIEWS

The role of Ca2+in the pathophysiology of pancreatitis

(2013) Julia V. Gerasimenko et al.   JOURNAL OF PHYSIOLOGY-LONDON

The return of the nucleus: transcriptional and epigenetic control of autophagy

(2013) Jens Füllgrabe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ca2+ release-activated Ca2+ channel blockade as a potential tool in antipancreatitis therapy

(2013) J. V. Gerasimenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy and pancreatitis

(2012) Anna S. Gukovskaya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB

(2012) Jose A. Martina et al.   Autophagy

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

(2012) Carmine Settembre et al.   EMBO JOURNAL

NFATc3 Regulates Trypsinogen Activation, Neutrophil Recruitment, and Tissue Damage in Acute Pancreatitis in Mice

(2012) Darbaz Awla et al.   GASTROENTEROLOGY

Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus

(2012) Peter A Banks et al.   GUT

Bile Acids Induce Pancreatic Acinar Cell Injury and Pancreatitis by Activating Calcineurin

(2012) Kamaldeen A. Muili et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impaired autophagy and organellar dysfunction in pancreatitis

(2012) Ilya Gukovsky et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Genetic and Pharmacologic Inhibition of the Ca2+ Influx Channel TRPC3 Protects Secretory Epithelia From Ca2+-Dependent Toxicity

(2011) Min Seuk Kim et al.   GASTROENTEROLOGY

Autophagy Regulation by the Nuclear Factor κB Signal Axis in Acute Pancreatitis

(2011) Shuli Yang et al.   PANCREAS

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Impaired autophagy underlies key pathological responses of acute pancreatitis

(2010) Ilya Gukovsky et al.   Autophagy

The acinar-ductal tango in the pathogenesis of acute pancreatitis

(2010) P. Hegyi et al.   GUT

Pancreatic acinar cell: New insights into the control of secretion

(2010) Jiun T. Low et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The regulation of autophagy - unanswered questions

(2010) Y. Chen et al.   JOURNAL OF CELL SCIENCE

Identification of candidate genes involved in endogenous protection mechanisms against acute pancreatitis in mice

(2009) Shinji Nakada et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ribosome-free Terminals of Rough ER Allow Formation of STIM1 Puncta and Segregation of STIM1 from IP3 Receptors

(2009) Gyorgy Lur et al.   CURRENT BIOLOGY

Deletion of TRPC3 in Mice Reduces Store-Operated Ca2+ Influx and the Severity of Acute Pancreatitis

(2009) Min Seuk Kim et al.   GASTROENTEROLOGY

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells

(2008) Daisuke Hashimoto et al.   JOURNAL OF CELL BIOLOGY

Acute pancreatitis

(2008) Jean-Louis Frossard et al.   LANCET

STIM1 Gates TRPC Channels, but Not Orai1, by Electrostatic Interaction

(2008) Weizhong Zeng et al.   MOLECULAR CELL

Polarized Calcium Signaling in Exocrine Gland Cells

(2007) Ole H. Petersen et al.   Annual Review of Physiology

Cholecystokinin Activates Pancreatic Calcineurin-NFAT Signaling In Vitro and In Vivo

(2007) Grzegorz T. Gurda et al.   MOLECULAR BIOLOGY OF THE CELL