Parathyroid Hormone-Related Peptide Elicits Peripheral TRPV1-dependent Mechanical Hypersensitivity

Pharmacological validation of voluntary gait and mechanical sensitivity assays associated with inflammatory and neuropathic pain in mice

(2018) Andrew J. Shepherd et al.   NEUROPHARMACOLOGY

TRPV1 and TRPA1 in cutaneous neurogenic and chronic inflammation: pro-inflammatory response induced by their activation and their sensitization

(2017) Olivier Gouin et al.   Protein & Cell

TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress

(2016) Gabriela Trevisan et al.   BRAIN

Peripheral Group I Metabotropic Glutamate Receptor Activation Leads to Muscle Mechanical Hyperalgesia Through TRPV1 Phosphorylation in the Rat

(2015) Man-Kyo Chung et al.   JOURNAL OF PAIN

Induction of thermal and mechanical hypersensitivity by parathyroid hormone–related peptide through upregulation of TRPV1 function and trafficking

(2015) Aaron D. Mickle et al.   PAIN

Modality-specific mechanisms of protein kinase C–induced hypersensitivity of TRPV1

(2015) Sen Wang et al.   PAIN

Spicing up the sensation of stretch: TRPV1 controls mechanosensitive Piezo channels

(2015) Christophe Altier   Science Signaling

Activation of TRPV1 channels inhibits mechanosensitive Piezo channel activity by depleting membrane phosphoinositides

(2015) Istvan Borbiro et al.   Science Signaling

Spicing up the sensation of stretch: TRPV1 controls mechanosensitive Piezo channels

(2015) Christophe Altier   Science Signaling

Activation of TRPV1 channels inhibits mechanosensitive Piezo channel activity by depleting membrane phosphoinositides

(2015) Istvan Borbiro et al.   Science Signaling

Molecular Signatures of Mouse TRPV1-Lineage Neurons Revealed by RNA-Seq Transcriptome Analysis

(2014) Samridhi C. Goswami et al.   JOURNAL OF PAIN

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

(2014) Sanjeev S. Ranade et al.   NATURE

Piezo2 is required for Merkel-cell mechanotransduction

(2014) Seung-Hyun Woo et al.   NATURE

The Neurobiology of Cancer Pain

(2014) Brian L. Schmidt   NEUROSCIENTIST

Prostate Cancer and Bone: The Elective Affinities

(2014) Nadia Rucci et al.   Biomed Research International

TRP Channels and Pain

(2013) David Julius   Annual Review of Cell and Developmental Biology

Identification of PTHrP(12-48) as a Plasma Biomarker Associated with Breast Cancer Bone Metastasis

(2013) C. L. Washam et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The puzzle of TRPV4 channelopathies

(2013) Bernd Nilius et al.   EMBO REPORTS

Increased TRPV4 Expression in Urinary Bladder and Lumbosacral Dorsal Root Ganglia in Mice with Chronic Overexpression of NGF in Urothelium

(2013) Beatrice M. Girard et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Phenotyping the Function of TRPV1-Expressing Sensory Neurons by Targeted Axonal Silencing

(2013) C. Brenneis et al.   JOURNAL OF NEUROSCIENCE

Bone cancer pain: Causes, consequences, and therapeutic opportunities

(2013) Patrick Mantyh   PAIN

4α-phorbol 12,13-didecanoate activates cultured mouse dorsal root ganglia neurons independently of TRPV4

(2012) R Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Evidence TRPV4 contributes to mechanosensitive ion channels in mouse skeletal muscle fibers

(2012) Tiffany C. Ho et al.   Channels

The multifaceted actions of PTHrP in skeletal metastasis

(2012) Fabiana N Soki et al.   Future Oncology

The C-Type Natriuretic Peptide Induces Thermal Hyperalgesia through a Noncanonical G  -dependent Modulation of TRPV1 Channel

(2012) L. Loo et al.   JOURNAL OF NEUROSCIENCE

Piezo proteins are pore-forming subunits of mechanically activated channels

(2012) Bertrand Coste et al.   NATURE

TRPV1 is important for mechanical and heat sensitivity in uninjured animals and development of heat hypersensitivity after muscle inflammation

(2012) Roxanne Y. Walder et al.   PAIN

Functional interactions between NMDA receptors and TRPV1 in trigeminal sensory neurons mediate mechanical hyperalgesia in the rat masseter muscle

(2012) Jongseok Lee et al.   PAIN

Inflammatory Signals Enhance Piezo2-Mediated Mechanosensitive Currents

(2012) Adrienne E. Dubin et al.   Cell Reports

Tissue Preparation and Immunostaining of Mouse Sensory Nerve Fibers Innervating Skin and Limb Bones

(2012) Andrew J. Shepherd et al.   Jove-Journal of Visualized Experiments

Transient receptor potential vanilloid 1 mediates pain in mice with severe sickle cell disease

(2011) C. A. Hillery et al.   BLOOD

Hematopoietic colony-stimulating factors: new players in tumor–nerve interactions

(2010) Sebastian Stösser et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Bone Metastases: Molecular Mechanisms and Novel Therapeutic Interventions

(2010) Dionysios J. Papachristou et al.   MEDICINAL RESEARCH REVIEWS

Involvement of Lysophosphatidic Acid in Bone Cancer Pain by Potentiation of TRPV1 via PKCe Pathway in Dorsal Root Ganglion Neurons

(2010) Hai-Li Pan et al.   Molecular Pain

TRPA1 Mediates Mechanical Currents in the Plasma Membrane of Mouse Sensory Neurons

(2010) Daniel Vilceanu et al.   PLoS One

The Ion Channel TRPA1 Is Required for Normal Mechanosensation and Is Modulated by Algesic Stimuli

(2009) Stuart M. Brierley et al.   GASTROENTEROLOGY

Parathyroid hormone 2 receptor is a functional marker of nociceptive myelinated fibers responsible for neuropathic pain

(2009) Misaki Matsumoto et al.   JOURNAL OF NEUROCHEMISTRY

Modulation of Transient Receptor Potential Vanilloid 4-Mediated Membrane Currents and Synaptic Transmission by Protein Kinase C

(2009) De-Shou Cao et al.   Molecular Pain

Hematopoietic colony–stimulating factors mediate tumor-nerve interactions and bone cancer pain

(2009) Matthias Schweizerhof et al.   NATURE MEDICINE

Contributions of Central and Peripheral TRPV1 Receptors to Mechanically Evoked and Spontaneous Firing of Spinal Neurons in Inflamed Rats

(2008) Steve McGaraughty et al.   JOURNAL OF NEUROPHYSIOLOGY

Interaction of Transient Receptor Potential Vanilloid 4, Integrin, and Src Tyrosine Kinase in Mechanical Hyperalgesia

(2008) N. Alessandri-Haber et al.   JOURNAL OF NEUROSCIENCE

Endogenous Tumor Necrosis Factor   (TNF ) Requires TNF Receptor Type 2 to Generate Heat Hyperalgesia in a Mouse Cancer Model

(2008) C. E. Constantin et al.   JOURNAL OF NEUROSCIENCE

Involvement of TRPV1 in Nociceptive Behavior in a Rat Model of Cancer Pain

(2008) Masamichi Shinoda et al.   JOURNAL OF PAIN

Transient receptor potential channels: targeting pain at the source

(2008) Ardem Patapoutian et al.   NATURE REVIEWS DRUG DISCOVERY