TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress

On the role of 4-hydroxynonenal in health and disease

(2015) Miklós Csala et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell–derived leukocyte elastase

(2015) Lucas Vicuña et al.   NATURE MEDICINE

Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain

(2014) Elizabeth A. Old et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential gene expression in proximal and distal nerve segments of rats with sciatic nerve injury during Wallerian degeneration

(2014) Dengbing Yao et al.   Neural Regeneration Research

Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1

(2014) Camilla Fusi et al.   Nature Communications

Trigeminal neuralgia

(2014) J. M. Zakrzewska et al.   BMJ-British Medical Journal

Transient Receptor Potential Ankyrin 1 Receptor Stimulation by Hydrogen Peroxide Is Critical to Trigger Pain During Monosodium Urate-Induced Inflammation in Rodents

(2013) Gabriela Trevisan et al.   ARTHRITIS AND RHEUMATISM

Differential diagnosis of facial pain and guidelines for management

(2013) J.M. Zakrzewska   BRITISH JOURNAL OF ANAESTHESIA

The Molecular Link Between C-C-Chemokine Ligand 2-Induced Leukocyte Recruitment and Hyperalgesia

(2013) Diana Pflücke et al.   JOURNAL OF PAIN

Differential Gene Expression Profiling and Biological Process Analysis in Proximal Nerve Segments after Sciatic Nerve Transection

(2013) Shiying Li et al.   PLoS One

The Connection of Monocytes and Reactive Oxygen Species in Pain

(2013) Dagmar Hackel et al.   PLoS One

Effect of pyrroloquinoline quinone on neuropathic pain following chronic constriction injury of the sciatic nerve in rats

(2012) Dezheng Gong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The classification and differential diagnosis of orofacial pain

(2012) Tara Renton et al.   Expert Review of Neurotherapeutics

Cyclotraxin-B, a New TrkB Antagonist, and Glial Blockade by Propentofylline, Equally Prevent and Reverse Cold Allodynia Induced by BDNF or Partial Infraorbital Nerve Constriction in Mice

(2012) Luis Constandil et al.   JOURNAL OF PAIN

TRPA1 and TRPV4 mediate paclitaxel-induced peripheral neuropathy in mice via a glutathione-sensitive mechanism

(2012) Serena Materazzi et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The ‘headache tree’ via umbellulone and TRPA1 activates the trigeminovascular system

(2011) Romina Nassini et al.   BRAIN

Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury

(2011) Andrew D Gaudet et al.   Journal of Neuroinflammation

Assessing nociceptive sensitivity in mouse models of inflammatory and neuropathic trigeminal pain

(2011) Agnieszka Krzyzanowska et al.   JOURNAL OF NEUROSCIENCE METHODS

Site-specific subtypes of macrophages recruited after peripheral nerve injury

(2011) Tadasuke Komori et al.   NEUROREPORT

Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation

(2011) Romina Nassini et al.   PAIN

Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation

(2011) Jun Chen et al.   PAIN

TRPA1 antagonists as potential analgesic drugs

(2011) E.L. Andrade et al.   PHARMACOLOGY & THERAPEUTICS

P2X4 receptor expression in a rat model of trigeminal neuropathic pain

(2010) Kunihiro Nakai et al.   NEUROREPORT

Attenuation of Mechanical Hypersensitivity by an Antagonist of the TRPA1 Ion Channel in Diabetic Animals

(2009) Hong Wei et al.   ANESTHESIOLOGY

Nitrooleic Acid, an Endogenous Product of Nitrative Stress, Activates Nociceptive Sensory Nerves via the Direct Activation of TRPA1

(2009) T. E. Taylor-Clark et al.   MOLECULAR PHARMACOLOGY

Nociceptive Signals Induce Trafficking of TRPA1 to the Plasma Membrane

(2009) Manuela Schmidt et al.   NEURON

Kinin B1 and B2 receptors contribute to orofacial heat hyperalgesia induced by infraorbital nerve constriction injury in mice and rats

(2009) Ana Paula Luiz et al.   NEUROPEPTIDES

The Contribution of TRPM8 and TRPA1 Channels to Cold Allodynia and Neuropathic Pain

(2009) Ombretta Caspani et al.   PLoS One

Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: a molecular mechanism of inflammatory pain

(2008) Shenglan Wang et al.   BRAIN

Edaravone, a free radical scavenger, is effective on neuropathic pain in rats

(2008) Yan-Fei Mao et al.   BRAIN RESEARCH

Activation of transient receptor potential ankyrin 1 by hydrogen peroxide

(2008) Yosuke Sawada et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Monocyte chemoattractant protein-1: A key mediator in inflammatory processes

(2008) Esther Melgarejo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

TRPA1 is a major oxidant sensor in murine airway sensory neurons

(2008) Bret F. Bessac et al.   JOURNAL OF CLINICAL INVESTIGATION

Transient Receptor Potential A1 Is a Sensory Receptor for Multiple Products of Oxidative Stress

(2008) D. A. Andersson et al.   JOURNAL OF NEUROSCIENCE

Partial Infraorbital Nerve Ligation as a Model of Trigeminal Nerve Injury in the Mouse: Behavioral, Neural, and Glial Reactions

(2008) Mei Xu et al.   JOURNAL OF PAIN

HC-030031, a TRPA1 Selective Antagonist, Attenuates Inflammatory- and Neuropathy-Induced Mechanical Hypersensitivity

(2008) Samer R Eid et al.   Molecular Pain