Photochemical syntheses, transformations, and bioorthogonal chemistry of trans-cycloheptene and sila trans-cycloheptene Ag(i) complexes

Uncatalyzed Carboboration of Seven-Membered-Ring trans-Alkenes: Formation of Air-Stable Trialkylboranes

(2017) Jillian R. Sanzone et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Computationally guided discovery of a reactive, hydrophilic trans-5-oxocene dienophile for bioorthogonal labeling

(2017) William D. Lambert et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Reactivity of Seven-Membered-Ring trans-Alkenes with Electrophiles

(2017) K. Woerpel et al.   SYNLETT

Optimized Tetrazine Derivatives for Rapid Bioorthogonal Decaging in Living Cells

(2016) Xinyuan Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Triggered Drug Release from an Antibody–Drug Conjugate Using Fast “Click-to-Release” Chemistry in Mice

(2016) Raffaella Rossin et al.   BIOCONJUGATE CHEMISTRY

Click Chemistry and Radiochemistry: The First 10 Years

(2016) Jan-Philip Meyer et al.   BIOCONJUGATE CHEMISTRY

[4+2] Cycloadditions of Seven-Membered-Ring trans-Alkenes: Decreasing Reactivity with Increasing Substitution of the Seven-Membered Ring

(2016) John Santucci et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Photochemical Formation of Dibenzosilacyclohept-4-yne for Cu-Free Click Chemistry with Azides and 1,2,4,5-Tetrazines

(2016) Marek Martínek et al.   ORGANIC LETTERS

Structure and Reactivity of an Isolable Seven-Membered-Ringtrans-Alkene

(2015) Brisa Hurlocker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Genetic code expansion enabled site-specific dual-color protein labeling: superresolution microscopy and beyond

(2015) Ivana Nikić et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

AlCl3-Catalyzed Ring Expansion Cascades of Bicyclic Cyclobutenamides Involving Highly Strained Cis,Trans-Cycloheptadienone Intermediates

(2015) Xiao-Na Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Systematic Evaluation of Bioorthogonal Reactions in Live Cells with Clickable HaloTag Ligands: Implications for Intracellular Imaging

(2015) Heather E. Murrey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ideal Bioorthogonal Reactions Using A Site-Specifically Encoded Tetrazine Amino Acid

(2015) Robert J. Blizzard et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inverse Electron-Demand Diels–Alder Bioorthogonal Reactions

(2015) Haoxing Wu et al.   Topics in Current Chemistry

Bioorthogonal Reactions for Labeling Proteins

(2014) Kathrin Lang et al.   ACS Chemical Biology

Finding the Right (Bioorthogonal) Chemistry

(2014) David M. Patterson et al.   ACS Chemical Biology

Click Chemistry in Complex Mixtures: Bioorthogonal Bioconjugation

(2014) Craig S. McKay et al.   CHEMISTRY & BIOLOGY

Planar Chiral Dialkoxysilane: Introduction of Inherent Chirality and High Reactivity in Conventional Achiral Alkene

(2014) Katsuhiko Tomooka et al.   CHEMISTRY-A EUROPEAN JOURNAL

Pretargeted imaging using bioorthogonal chemistry in mice

(2014) Raffaella Rossin et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Diels-Alder reaction–triggered bioorthogonal protein decaging in living cells

(2014) Jie Li et al.   Nature Chemical Biology

Conformationally strained trans-cyclooctene with improved stability and excellent reactivity in tetrazine ligation

(2014) Ampofo Darko et al.   Chemical Science

Click to Release: Instantaneous Doxorubicin Elimination upon Tetrazine Ligation

(2013) Ron M. Versteegen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal chemistry: strategies and recent developments

(2013) Carlo P. Ramil et al.   CHEMICAL COMMUNICATIONS

trans-Cyclooctene—a stable, voracious dienophile for bioorthogonal labeling

(2013) Ramajeyam Selvaraj et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Synthesis and Reactivity of Dibenzoselenacycloheptynes

(2013) Gabriela de Almeida et al.   ORGANIC LETTERS

Thiacycloalkynes for Copper-Free Click Chemistry

(2012) Gabriela de Almeida et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diastereoselective Synthesis of Seven-Membered-Ring trans-Alkenes from Dienes and Aldehydes by Silylene Transfer

(2012) Margaret A. Greene et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biomedical Applications of Tetrazine Cycloadditions

(2011) Neal K. Devaraj et al.   ACCOUNTS OF CHEMICAL RESEARCH

Design and Synthesis of Highly Reactive Dienophiles for the Tetrazine–trans-Cyclooctene Ligation

(2011) Michael T. Taylor et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total synthesis of hyacinthacine A2: stereocontrolled 5-aza-cyclooctene photoisomerization and transannular hydroamination with planar-to-point chirality transfer

(2011) Maksim Royzen et al.   Chemical Science

Bioorthogonal Turn-On Probes for Imaging Small Molecules inside Living Cells

(2010) Neal K. Devaraj et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis

(2008) Georgyi V. Los et al.   ACS Chemical Biology

A Photochemical Synthesis of Functionalizedtrans-Cyclooctenes Driven by Metal Complexation

(2008) Maksim Royzen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

(2008) Melissa L. Blackman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intermolecular Hydroaminations via Strained (E)-Cycloalkenes

(2007) Joseph Moran et al.   JOURNAL OF ORGANIC CHEMISTRY