Functional macrophages and gastrointestinal disorders

Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function

(2017) Kazuyuki Takata et al.   IMMUNITY

MS4A4A: a novel cell surface marker for M2 macrophages and plasma cells

(2017) Ratna Sanyal et al.   IMMUNOLOGY AND CELL BIOLOGY

Tumor-associated macrophages: implications in cancer immunotherapy

(2017) Amy J Petty et al.   Immunotherapy

Tumor-recruited M2 macrophages promote gastric and breast cancer metastasis via M2 macrophage-secreted CHI3L1 protein

(2017) Yulei Chen et al.   Journal of Hematology & Oncology

IL-6 Regulates M2 Polarization and Local Proliferation of Adipose Tissue Macrophages in Obesity

(2017) Julia Braune et al.   JOURNAL OF IMMUNOLOGY

The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis

(2017) Michele Biagioli et al.   JOURNAL OF IMMUNOLOGY

Immune microenvironment of gliomas

(2017) Anna Gieryng et al.   LABORATORY INVESTIGATION

Resident macrophages in the healthy and inflamed intestinal muscularis externa

(2017) Sven Wehner et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Macrophages in vascular inflammation and atherosclerosis

(2017) Clement Cochain et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Targeting tumor associated macrophages: The new challenge for nanomedicine

(2017) Fernando Torres Andón et al.   SEMINARS IN IMMUNOLOGY

DHRS9 Is a Stable Marker of Human Regulatory Macrophages

(2017) Paloma Riquelme et al.   TRANSPLANTATION

The expression of NKG2D on porcine IEL and its possible relation to the adaptive intestinal immune system

(2017) Sara Altmeyer et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

All-Trans Retinoic Acid Prevents Osteosarcoma Metastasis by Inhibiting M2 Polarization of Tumor-Associated Macrophages

(2017) Qian Zhou et al.   Cancer Immunology Research

MFG-E8 Drives Melanoma Growth by Stimulating Mesenchymal Stromal Cell–Induced Angiogenesis and M2 Polarization of Tumor-Associated Macrophages

(2016) Kazuya Yamada et al.   CANCER RESEARCH

Protective role of G-CSF in dextran sulfate sodium-induced acute colitis through generating gut-homing macrophages

(2016) Shahab Meshkibaf et al.   CYTOKINE

CD40 in Retinal Müller Cells Induces P2X 7 -Dependent Cytokine Expression in Macrophages/Microglia in Diabetic Mice and Development of Early Experimental Diabetic Retinopathy

(2016) Jose-Andres C. Portillo et al.   DIABETES

Alterations to chromatin in intestinal macrophages link IL-10 deficiency to inappropriate inflammatory responses

(2016) Jeremy M. Simon et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Effect of Microbiota and the Immune System on the Development and Organization of the Enteric Nervous System

(2016) Yuuki Obata et al.   GASTROENTEROLOGY

Role of Monocytes and Intestinal Macrophages in Crohnʼs Disease and Ulcerative Colitis

(2016) Susanne T. Gren et al.   INFLAMMATORY BOWEL DISEASES

Lipoxin A4selectively programs the profile of M2 tumor-associated macrophages which favour control of tumor progression

(2016) R. L. Simões et al.   INTERNATIONAL JOURNAL OF CANCER

Poncirin and its metabolite ponciretin attenuate colitis in mice by inhibiting LPS binding on TLR4 of macrophages and correcting Th17/Treg imbalance

(2016) Geum-Dan Kang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Alternatively Activated Macrophages Boost Induced Regulatory T and Th17 Cell Responses during Immunotherapy for Colitis

(2016) Dipica Haribhai et al.   JOURNAL OF IMMUNOLOGY

Transient receptor potential melastatin 8 ion channel in macrophages modulates colitis through a balance-shift in TNF-alpha and interleukin-10 production

(2016) M Khalil et al.   Mucosal Immunology

Smad7 interrupts TGF-β signaling in intestinal macrophages and promotes inflammatory activation of these cells during necrotizing enterocolitis

(2016) Krishnan MohanKumar et al.   PEDIATRIC RESEARCH

The Extracellular Calcium-Sensing Receptor in the Intestine: Evidence for Regulation of Colonic Absorption, Secretion, Motility, and Immunity

(2016) Lieqi Tang et al.   Frontiers in Physiology

Mesenchymal Stem Cells Recruit Macrophages to Alleviate Experimental Colitis Through TGFβ1

(2015) Weixin Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Epigenetic pathways in macrophages emerge as novel targets in atherosclerosis

(2015) Annette E. Neele et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Tumor-associated macrophages of the M2 phenotype contribute to progression in gastric cancer with peritoneal dissemination

(2015) Takahisa Yamaguchi et al.   Gastric Cancer

The interaction of anticancer therapies with tumor-associated macrophages

(2015) Alberto Mantovani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Gut-Associated Lymphoid Tissues in the Small Intestine, Not the Large Intestine, Play a Major Role in Oral Prion Disease Pathogenesis

(2015) David S. Donaldson et al.   JOURNAL OF VIROLOGY

CD11c+ monocyte/macrophages promote chronic Helicobacter hepaticus-induced intestinal inflammation through the production of IL-23

(2015) I C Arnold et al.   Mucosal Immunology

Intestinal CD169+ macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes

(2015) Kenichi Asano et al.   Nature Communications

IL-10 engages macrophages to shift Th17 cytokine dependency and pathogenicity during T-cell-mediated colitis

(2015) Bofeng Li et al.   Nature Communications

IL-10-producing intestinal macrophages prevent excessive antibacterial innate immunity by limiting IL-23 synthesis

(2015) Petra Krause et al.   Nature Communications

Intestinal macrophages arising from CCR2+ monocytes control pathogen infection by activating innate lymphoid cells

(2015) Sang-Uk Seo et al.   Nature Communications

Mulberry fruit prevents LPS-induced NF-κB/pERK/MAPK signals in macrophages and suppresses acute colitis and colorectal tumorigenesis in mice

(2015) Zhengjiang Qian et al.   Scientific Reports

TNF Counterbalances the Emergence of M2 Tumor Macrophages

(2015) Franz Kratochvill et al.   Cell Reports

Multiple myeloma cells recruit tumor-supportive macrophages through the CXCR4/CXCL12 axis and promote their polarization toward the M2 phenotype

(2015) Katia Beider et al.   Oncotarget

Granulocyte macrophage colony-stimulating factor and the intestinal innate immune cell homeostasis in Crohn's disease

(2014) Jan Däbritz   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Interkeukin-34, a cytokine crucial for the differentiation and maintenance of tissue resident macrophages and Langerhans cells

(2014) Yaming Wang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Macrophages in intestinal homeostasis and inflammation

(2014) Calum C. Bain et al.   IMMUNOLOGICAL REVIEWS

Cross-talk Between RORγt+ Innate Lymphoid Cells and Intestinal Macrophages Induces Mucosal IL-22 Production in Crohnʼs Disease

(2014) Shinta Mizuno et al.   INFLAMMATORY BOWEL DISEASES

Optimization of murine small intestine leukocyte isolation for global immune phenotype analysis

(2014) Andrew W. Goodyear et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Dynamic Changes in Macrophage Activation and Proliferation during the Development and Resolution of Intestinal Inflammation

(2014) Matthew C. Little et al.   JOURNAL OF IMMUNOLOGY

Resident Alveolar Macrophages Suppress, whereas Recruited Monocytes Promote, Allergic Lung Inflammation in Murine Models of Asthma

(2014) Zbigniew Zasłona et al.   JOURNAL OF IMMUNOLOGY

Small Intestinal Intraepithelial TCRγδ+ T Lymphocytes Are Present in the Premature Intestine but Selectively Reduced in Surgical Necrotizing Enterocolitis

(2014) Jörn-Hendrik Weitkamp et al.   PLoS One

Microbiota-Dependent Crosstalk Between Macrophages and ILC3 Promotes Intestinal Homeostasis

(2014) A. Mortha et al.   SCIENCE

Intestinal macrophages and dendritic cells: what's the difference?

(2014) Vuk Cerovic et al.   TRENDS IN IMMUNOLOGY

The Phosphate Exporter xpr1b Is Required for Differentiation of Tissue-Resident Macrophages

(2014) Ana M. Meireles et al.   Cell Reports

Incomplete Deletion of IL-4Rα by LysMCre Reveals Distinct Subsets of M2 Macrophages Controlling Inflammation and Fibrosis in Chronic Schistosomiasis

(2014) Kevin M. Vannella et al.   PLoS Pathogens

Hepatitis B Virus Infection and Immunopathogenesis in a Humanized Mouse Model: Induction of Human-Specific Liver Fibrosis and M2-Like Macrophages

(2014) Moses T. Bility et al.   PLoS Pathogens

Bone marrow-derived alternatively activated macrophages reduce colitis without promoting fibrosis: participation of IL-10

(2013) Gabriella Leung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

A Single Strain of Clostridium butyricum Induces Intestinal IL-10-Producing Macrophages to Suppress Acute Experimental Colitis in Mice

(2013) Atsushi Hayashi et al.   Cell Host & Microbe

Mucus and the Goblet Cell

(2013) Malin E.V. Johansson et al.   DIGESTIVE DISEASES

IL-13Rα1 is a surface marker for M2 macrophages influencing their differentiation and function

(2013) Mermagya Dhakal et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Activated Intestinal Macrophages in Patients with Cirrhosis Release NO and IL-6 that May Disrupt Intestinal Barrier Function

(2013) Elizabeth C. Goode et al.   GASTROENTEROLOGY

Nucleotide-Binding Oligomerization Domain 2 Signaling Promotes Hyperresponsive Macrophages and Colitis in IL-10-Deficient Mice

(2013) J. Jamontt et al.   JOURNAL OF IMMUNOLOGY

Identification of TLR10 as a Key Mediator of the Inflammatory Response to Listeria monocytogenes in Intestinal Epithelial Cells and Macrophages

(2013) T. Regan et al.   JOURNAL OF IMMUNOLOGY

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(2013) Tarcio Braga et al.   MOLECULAR MEDICINE

Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages

(2013) Takashi Satoh et al.   NATURE

Dietary Oleic Acid Increases M2 Macrophages in the Mesenteric Adipose Tissue

(2013) Christina Camell et al.   PLoS One

M2 Macrophages Activate WNT Signaling Pathway in Epithelial Cells: Relevance in Ulcerative Colitis

(2013) Jesús Cosín-Roger et al.   PLoS One

Linking tumor-associated macrophages, inflammation, and intestinal tumorigenesis: role of MCP-1

(2012) Jamie L. McClellan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Intestinal CD103− dendritic cells migrate in lymph and prime effector T cells

(2012) V Cerovic et al.   Mucosal Immunology

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

Intestinal macrophages - specialised adaptation to a unique environment

(2011) Calum C. Bain et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Soyasaponin Ab Ameliorates Colitis by Inhibiting the Binding of Lipopolysaccharide (LPS) to Toll-like Receptor (TLR)4 on Macrophages

(2011) In-Ah Lee et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Mucosal Macrophages in Intestinal Homeostasis and Inflammation

(2011) Allan McI Mowat et al.   Journal of Innate Immunity

Management of gut inflammation through the manipulation of intestinal dendritic cells and macrophages?

(2011) Liat Bar-On et al.   SEMINARS IN IMMUNOLOGY

Mechanical strain and TLR4 synergistically induce cell-specific inflammatory gene expression in intestinal smooth muscle cells and peritoneal macrophages

(2010) Sven Wehner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Targeted imaging of tumor-associated M2 macrophages using a macromolecular contrast agent PG-Gd-NIR813

(2010) Marites P. Melancon et al.   BIOMATERIALS

An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation

(2010) K. P. A. MacDonald et al.   BLOOD

The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time

(2010) Junliang Ma et al.   BMC CANCER

The role of the macrophage in sentinel responses in intestinal immunity

(2010) Shehzad Z Sheikh et al.   CURRENT OPINION IN GASTROENTEROLOGY

Dynamic, M2-Like Remodeling Phenotypes of CD11c+ Adipose Tissue Macrophages During High-Fat Diet-Induced Obesity in Mice

(2010) M. E. Shaul et al.   DIABETES

The puzzle of intestinal lamina propria dendritic cells and macrophages

(2010) Oliver Pabst et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

An Independent Subset of TLR Expressing CCR2-Dependent Macrophages Promotes Colonic Inflammation

(2010) A. M. Platt et al.   JOURNAL OF IMMUNOLOGY

Intestinal macrophages and response to microbial encroachment

(2010) P D Smith et al.   Mucosal Immunology

Infiltration of thymidine phosphorylase-positive macrophages is closely associated with tumor angiogenesis and survival in intestinal type gastric cancer

(2010) Kawahara   ONCOLOGY REPORTS

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

Regulatory Lymphocytes and Intestinal Inflammation

(2009) Ana Izcue et al.   Annual Review of Immunology

Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice

(2009) S. Fujisaka et al.   DIABETES

Alveolar macrophages in allergic asthma: An expression signature characterized by heat shock protein pathways

(2009) Anne-Marie Madore et al.   HUMAN IMMUNOLOGY

Human Adipose Tissue Macrophages: M1 and M2 Cell Surface Markers in Subcutaneous and Omental Depots and after Weight Loss

(2009) Judith Aron-Wisnewsky et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions

(2009) Olga Schulz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Microbial Influences in Inflammatory Bowel Diseases

(2008) R. Balfour Sartor   GASTROENTEROLOGY

Unique CD14+ intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-γ axis

(2008) Nobuhiko Kamada et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics

(2008) Naoki Umemura et al.   JOURNAL OF LEUKOCYTE BIOLOGY

TGF-β1 and Smad7 in the regulation of IBD

(2008) G Monteleone et al.   Mucosal Immunology

Recent progress in understanding the phenotype and function of intestinal dendritic cells and macrophages

(2008) B Kelsall   Mucosal Immunology

A critical function for CD200 in lung immune homeostasis and the severity of influenza infection

(2008) Robert J Snelgrove et al.   NATURE IMMUNOLOGY

Gelatinase B/MMP-9 as an inflammatory marker enzyme in mouse zymosan peritonitis: Comparison of phase-specific and cell-specific production by mast cells, macrophages and neutrophils

(2007) Elzbieta Kolaczkowska et al.   IMMUNOBIOLOGY