Role of Monocytes and Intestinal Macrophages in Crohnʼs Disease and Ulcerative Colitis

MicroRNA expression profiling of human blood monocyte subsets highlights functional differences

(2015) Truong-Minh Dang et al.   IMMUNOLOGY

IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases

(2015) Michele W L Teng et al.   NATURE MEDICINE

A Single-Cell Gene-Expression Profile Reveals Inter-Cellular Heterogeneity within Human Monocyte Subsets

(2015) Susanne T. Gren et al.   PLoS One

Macrophages in intestinal homeostasis and inflammation

(2014) Calum C. Bain et al.   IMMUNOLOGICAL REVIEWS

6-Mercaptopurine Reduces Macrophage Activation and Gut Epithelium Proliferation Through Inhibition of GTPase Rac1

(2014) Goran Marinković et al.   INFLAMMATORY BOWEL DISEASES

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

(2014) Elisa Gomez Perdiguero et al.   NATURE

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

(2014) Calum C Bain et al.   NATURE IMMUNOLOGY

Ontogeny of Myeloid Cells

(2014) Ismé De Kleer et al.   Frontiers in Immunology

β7 integrins are required to give rise to intestinal mononuclear phagocytes with tolerogenic potential

(2013) Eduardo J Villablanca et al.   GUT

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

CD14hi HLA-DRdim macrophages, with a resemblance to classical blood monocytes, dominate inflamed mucosa in Crohnˈs disease

(2013) Susanne Thiesen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Peripheral Monocyte Functions and Activation in Patients with Quiescent Crohn’s Disease

(2013) David Schwarzmaier et al.   PLoS One

CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis

(2012) Samira Tamoutounour et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Ly6Chi Monocytes in the Inflamed Colon Give Rise to Proinflammatory Effector Cells and Migratory Antigen-Presenting Cells

(2012) Ehud Zigmond et al.   IMMUNITY

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

The three human monocyte subsets: implications for health and disease

(2012) Kok Loon Wong et al.   IMMUNOLOGIC RESEARCH

Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors

(2012) C C Bain et al.   Mucosal Immunology

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

The CD14bright CD16+ monocyte subset is expanded in rheumatoid arthritis and promotes expansion of the Th17 cell population

(2011) Manuela Rossol et al.   ARTHRITIS AND RHEUMATISM

SuperSAGE evidence for CD14++CD16+ monocytes as a third monocyte subset

(2011) A. M. Zawada et al.   BLOOD

Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets

(2011) K. L. Wong et al.   BLOOD

CX3CR1 defines functionally distinct intestinal mononuclear phagocyte subsets which maintain their respective functions during homeostatic and inflammatory conditions

(2011) Benjamin Weber et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Antibodies Against Tumor Necrosis Factor (TNF) Induce T-Cell Apoptosis in Patients With Inflammatory Bowel Diseases via TNF Receptor 2 and Intestinal CD14+ Macrophages

(2011) Raja Atreya et al.   GASTROENTEROLOGY

Intestinal Tolerance Requires Gut Homing and Expansion of FoxP3+ Regulatory T Cells in the Lamina Propria

(2011) Usriansyah Hadis et al.   IMMUNITY

Bone Marrow Mesenchymal Stem and Progenitor Cells Induce Monocyte Emigration in Response to Circulating Toll-like Receptor Ligands

(2011) Chao Shi et al.   IMMUNITY

The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C− monocytes

(2011) Richard N Hanna et al.   NATURE IMMUNOLOGY

Nomenclature of monocytes and dendritic cells in blood

(2010) L. Ziegler-Heitbrock et al.   BLOOD

CD14++CD16+ monocytes and cardiovascular outcome in patients with chronic kidney disease

(2010) Kyrill S. Rogacev et al.   EUROPEAN HEART JOURNAL

Human CD14dim Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors

(2010) Jérôme Cros et al.   IMMUNITY

Inflammation Anergy in Human Intestinal Macrophages Is Due to Smad-induced IκBα Expression and NF-κB Inactivation

(2010) Lesley E. Smythies et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Independent Subset of TLR Expressing CCR2-Dependent Macrophages Promotes Colonic Inflammation

(2010) A. M. Platt et al.   JOURNAL OF IMMUNOLOGY

Model of colonic inflammation: Immune modulatory mechanisms in inflammatory bowel disease

(2010) Katherine Wendelsdorf et al.   JOURNAL OF THEORETICAL BIOLOGY

Intestinal macrophages and response to microbial encroachment

(2010) P D Smith et al.   Mucosal Immunology

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets

(2009) Petronela Ancuta et al.   BMC GENOMICS

Intestinal Lamina Propria Dendritic Cell Subsets Have Different Origin and Functions

(2009) Chen Varol et al.   IMMUNITY

Origin of the Lamina Propria Dendritic Cell Network

(2009) Milena Bogunovic et al.   IMMUNITY

TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria

(2009) Elsa-Noah N'Diaye et al.   JOURNAL OF CELL BIOLOGY