Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Iron Chelators for the Treatment of Cancer

(2012) Y. Yu et al.   CURRENT MEDICINAL CHEMISTRY

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites

(2012) Frédérick A Mallette et al.   EMBO JOURNAL

The Iron Chelators Dp44mT and DFO Inhibit TGF-β-induced Epithelial-Mesenchymal Transition via Up-Regulation of N-Myc Downstream-regulated Gene 1 (NDRG1)

(2012) Zhiqiang Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Tumor Suppressor p53 and HCT116 Cell Physiology by Histone Demethylase JMJD2D/KDM4D

(2012) Tae-Dong Kim et al.   PLoS One

Analysis of global DNA methylation by hydrophilic interaction ultra high-pressure liquid chromatography tandem mass spectrometry

(2011) Jun-jie Zhang et al.   ANALYTICAL BIOCHEMISTRY

Histone Demethylase LSD1 Is a Folate-Binding Protein

(2011) Zigmund Luka et al.   BIOCHEMISTRY

A novel transferrin receptor-targeted hybrid peptide disintegrates cancer cell membrane to induce rapid killing of cancer cells

(2011) Megumi Kawamoto et al.   BMC CANCER

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Ironing Out Cancer

(2011) S. V. Torti et al.   CANCER RESEARCH

An Iron Regulatory Gene Signature Predicts Outcome in Breast Cancer

(2011) L. D. Miller et al.   CANCER RESEARCH

The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), upregulates p21 via p53-independent mechanisms

(2011) Zaklina Kovacevic et al.   CARCINOGENESIS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation

(2011) H. Wu et al.   GENES & DEVELOPMENT

Cellular Iron Depletion and the Mechanisms Involved in the Iron-dependent Regulation of the Growth Arrest and DNA Damage Family of Genes

(2011) Federica Saletta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cells

(2011) Tae-Dong Kim et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Phosphorylation of SMC1 by ATR is required for desferrioxamine (DFO)-induced apoptosis

(2011) E Y So et al.   Cell Death & Disease

Chromatin remodeling regulation by small molecules and metabolites

(2010) Giosalba Burgio et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Role of ferritin alterations in human breast cancer cells

(2010) Svitlana I. Shpyleva et al.   BREAST CANCER RESEARCH AND TREATMENT

Histone Methyl Transferases and Demethylases; Can They Link Metabolism and Transcription?

(2010) Raffaele Teperino et al.   Cell Metabolism

Structural insights into histone lysine demethylation

(2010) Haifeng Hou et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structural studies on human 2-oxoglutarate dependent oxygenases

(2010) Michael A McDonough et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Trimethylation of histone H3 lysine 4 impairs methylation of histone H3 lysine 9

(2010) Olivier Binda et al.   Epigenetics

Conserved Antagonism between JMJD2A/KDM4A and HP1γ during Cell Cycle Progression

(2010) Joshua C. Black et al.   MOLECULAR CELL

Ferroportin and Iron Regulation in Breast Cancer Progression and Prognosis

(2010) Z. K. Pinnix et al.   Science Translational Medicine

Pomalidomide and Lenalidomide Induce p21WAF-1 Expression in Both Lymphoma and Multiple Myeloma through a LSD1-Mediated Epigenetic Mechanism

(2009) L. Escoubet-Lozach et al.   CANCER RESEARCH

The Iron Chelator Dp44mT Causes DNA Damage and Selective Inhibition of Topoisomerase II  in Breast Cancer Cells

(2009) V. A. Rao et al.   CANCER RESEARCH

Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α

(2008) Patrick J. Pollard et al.   BIOCHEMICAL JOURNAL

Does iron have a role in breast cancer?

(2008) Xi Huang   LANCET ONCOLOGY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols