Essential but toxic: Controlling the flux of iron in the body

Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses

(2011) Z. Zhang et al.   BLOOD

Hepcidin and iron regulation, 10 years later

(2011) T. Ganz   BLOOD

Interactions Between Ferroportin and Hephaestin in Rat Enterocytes Are Reduced After Iron Ingestion

(2011) Kwo–Yih Yeh et al.   GASTROENTEROLOGY

Reduced Expression of Ferroportin-1 Mediates Hyporesponsiveness of Suckling Rats to Stimuli That Reduce Iron Absorption

(2011) Deepak Darshan et al.   GASTROENTEROLOGY

Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease

(2010) James A. Duce et al.   CELL

Molecular basis of iron-loading disorders

(2010) Deepak Darshan et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Identification of Zyklopen, a New Member of the Vertebrate Multicopper Ferroxidase Family, and Characterization in Rodents and Human Cells

(2010) Huijun Chen et al.   JOURNAL OF NUTRITION

The Role of Hepcidin in Iron Metabolism

(2009) Elizabeta Nemeth et al.   ACTA HAEMATOLOGICA

Regulation of Hepcidin and Iron-Overload Disease

(2009) Pauline L. Lee et al.   Annual Review of Pathology-Mechanisms of Disease

Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells

(2009) T. Tanno et al.   BLOOD

Intestinal Hypoxia-Inducible Transcription Factors Are Essential for Iron Absorption following Iron Deficiency

(2009) Yatrik M. Shah et al.   Cell Metabolism

A Ferroportin Transcript that Lacks an Iron-Responsive Element Enables Duodenal and Erythroid Precursor Cells to Evade Translational Repression

(2009) De-Liang Zhang et al.   Cell Metabolism

Iron absorption and metabolism

(2009) Gregory J Anderson et al.   CURRENT OPINION IN GASTROENTEROLOGY

Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload

(2009) Daniel F. Wallace et al.   HEPATOLOGY

HIF-2α, but not HIF-1α, promotes iron absorption in mice

(2009) Maria Mastrogiannaki et al.   JOURNAL OF CLINICAL INVESTIGATION

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

(2009) Delphine Meynard et al.   NATURE GENETICS

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

(2009) Billy Andriopoulos Jr et al.   NATURE GENETICS

Iron Homeostasis in the Neonate

(2009) K. J. Collard   PEDIATRICS

Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis

(2008) A. R. Folgueras et al.   BLOOD

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

(2008) L. Kautz et al.   BLOOD

Two nonsense mutations in the TMPRSS6 gene in a patient with microcytic anemia and iron deficiency

(2008) F. Guillem et al.   BLOOD

Regulation of Iron Absorption in Hemoglobinopathies

(2008) Gideon Rechavi et al.   CURRENT MOLECULAR MEDICINE

Copper and Iron Transport Across the Placenta: Regulation and Interactions

(2008) H. J. McArdle et al.   JOURNAL OF NEUROENDOCRINOLOGY

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

(2008) Karin E Finberg et al.   NATURE GENETICS

Iron-Overload–Related Disease inHFEHereditary Hemochromatosis

(2008) Katrina J. Allen et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency

(2008) X. Du et al.   SCIENCE

A Heme Export Protein Is Required for Red Blood Cell Differentiation and Iron Homeostasis

(2008) S. B. Keel et al.   SCIENCE