Recruitment and reinforcement: maintaining epigenetic silencing

Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines

(2017) Xueyin Wang et al.   MOLECULAR CELL

hnRNPK Recruits PCGF3/5-PRC1 to the Xist RNA B-Repeat to Establish Polycomb-Mediated Chromosomal Silencing

(2017) Greta Pintacuda et al.   MOLECULAR CELL

Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription

(2017) Gloria Jih et al.   NATURE

Polycomb complexes in X chromosome inactivation

(2017) Neil Brockdorff   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

PCGF3/5–PRC1 initiates Polycomb recruitment in X chromosome inactivation

(2017) Mafalda Almeida et al.   SCIENCE

Propagation of Polycomb-repressed chromatin requires sequence-specific recruitment to DNA

(2017) Friederike Laprell et al.   SCIENCE

Causal role for inheritance of H3K27me3 in maintaining the OFF state of a Drosophila HOX gene

(2017) Rory T. Coleman et al.   SCIENCE

DNA sequence-dependent epigenetic inheritance of gene silencing and histone H3K9 methylation

(2017) Xiaoyi Wang et al.   SCIENCE

Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome association and RNA:DNA hybrid formation

(2017) Oscar Velazquez Camacho et al.   eLife

Dynamics of epigenetic regulation at the single-cell level

(2016) L. Bintu et al.   SCIENCE

Emerging roles of non-coding RNAs in epigenetic regulation

(2016) Juan Chen et al.   Science China-Life Sciences

Maintenance of Epigenetic Information

(2016) Geneviève Almouzni et al.   Cold Spring Harbor Perspectives in Biology

Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2

(2016) Sarah Cooper et al.   Nature Communications

Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2

(2016) Neil Justin et al.   Nature Communications

The Chp1 chromodomain binds the H3K9me tail and the nucleosome core to assemble heterochromatin

(2016) Manuel Zocco et al.   Cell Discovery

Recognition of H3K9 methylation by GLP is required for efficient establishment of H3K9 methylation, rapid target gene repression, and mouse viability

(2015) Nan Liu et al.   GENES & DEVELOPMENT

Two distinct modes for propagation of histone PTMs across the cell cycle

(2015) Constance Alabert et al.   GENES & DEVELOPMENT

Toward a Consensus on the Binding Specificity and Promiscuity of PRC2 for RNA

(2015) Chen Davidovich et al.   MOLECULAR CELL

RNA-mediated epigenetic regulation of gene expression

(2015) Daniel Holoch et al.   NATURE REVIEWS GENETICS

Contribution of epigenetics in diabetic retinopathy

(2015) Renu A. Kowluru et al.   Science China-Life Sciences

Autism spectrum disorder model mice: Focus on copy number variation and epigenetics

(2015) Nobuhiro Nakai et al.   Science China-Life Sciences

RNAi and Heterochromatin Assembly

(2015) Robert Martienssen et al.   Cold Spring Harbor Perspectives in Biology

You are never alone: crosstalk among epigenetic players

(2015) Cheng-Zhi Wang et al.   Science Bulletin

Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome

(2014) Simão Teixeira da Rocha et al.   MOLECULAR CELL

Redundant Mechanisms to Form Silent Chromatin at Pericentromeric Regions Rely on BEND3 and DNA Methylation

(2014) Nehmé Saksouk et al.   MOLECULAR CELL

Dynamic and static maintenance of epigenetic memory in pluripotent and somatic cells

(2014) Zohar Shipony et al.   NATURE

What are memories made of? How Polycomb and Trithorax proteins mediate epigenetic memory

(2014) Philipp A. Steffen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression

(2014) Reinhard Kalb et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond

(2013) Stephane E. Castel et al.   NATURE REVIEWS GENETICS

Promiscuous RNA binding by Polycomb repressive complex 2

(2013) Chen Davidovich et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells

(2013) Syuzo Kaneko et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Histone Mutant Reproduces the Phenotype Caused by Loss of Histone-Modifying Factor Polycomb

(2013) A. R. Pengelly et al.   SCIENCE

Specificity of Dnmt1 for Methylation of Hemimethylated CpG Sites Resides in Its Catalytic Domain

(2012) Pavel Bashtrykov et al.   CHEMISTRY & BIOLOGY

Epigenetic inheritance mediated by histone lysine methylation: maintaining transcriptional states without the precise restoration of marks?

(2012) C. Huang et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation

(2012) J. Song et al.   SCIENCE

Epigenetic inheritance: Uncontested?

(2011) Bing Zhu et al.   CELL RESEARCH

Chromatin higher-order structures and gene regulation

(2011) Guohong Li et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

A model for mitotic inheritance of histone lysine methylation

(2011) Mo Xu et al.   EMBO REPORTS

Bookmarking the Genome: Maintenance of Epigenetic Information

(2011) Sayyed K. Zaidi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1)

(2011) K. Takeshita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone modification: cause or cog?

(2011) Steven Henikoff et al.   TRENDS IN GENETICS

Genomic Prevalence of Heterochromatic H3K9me2 and Transcription Do Not Discriminate Pluripotent from Terminally Differentiated Cells

(2011) Florian Lienert et al.   PLoS Genetics

Epigenetic inheritance through self-recruitment of the polycomb repressive complex 2

(2010) Klaus Hansen et al.   Epigenetics

DNA methylation and the formation of heterochromatin in Neurospora crassa

(2010) M R Rountree et al.   HEREDITY

Establishing, maintaining and modifying DNA methylation patterns in plants and animals

(2010) Julie A. Law et al.   NATURE REVIEWS GENETICS

Histone modification levels are predictive for gene expression

(2010) R. Karlic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation

(2010) J. Song et al.   SCIENCE

Partitioning of Histone H3-H4 Tetramers During DNA Replication-Dependent Chromatin Assembly

(2010) M. Xu et al.   SCIENCE

2-D Structure of the A Region of Xist RNA and Its Implication for PRC2 Association

(2010) Sylvain Maenner et al.   PLOS BIOLOGY

Epigenetics: heterochromatin meets RNAi

(2009) Ingela Djupedal et al.   CELL RESEARCH

In VivoResidue-specific Histone Methylation Dynamics

(2009) Barry M. Zee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-Affinity Binding of Chp1 Chromodomain to K9 Methylated Histone H3 Is Required to Establish Centromeric Heterochromatin

(2009) Thomas Schalch et al.   MOLECULAR CELL

Role of the polycomb protein EED in the propagation of repressive histone marks

(2009) Raphael Margueron et al.   NATURE

Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells

(2009) Bo Wen et al.   NATURE GENETICS

Reassessing the abundance of H3K9me2 chromatin domains in embryonic stem cells

(2009) Guillaume J Filion et al.   NATURE GENETICS

Epigenetic inheritance during the cell cycle

(2009) Aline V. Probst et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Establishment of Histone Modifications after Chromatin Assembly

(2009) Annette N. D. Scharf et al.   NUCLEIC ACIDS RESEARCH

Direct Interaction between DNA Methyltransferase DIM-2 and HP1 Is Required for DNA Methylation in Neurospora crassa

(2008) S. Honda et al.   MOLECULAR AND CELLULAR BIOLOGY

Kcnq1ot1 Antisense Noncoding RNA Mediates Lineage-Specific Transcriptional Silencing through Chromatin-Level Regulation

(2008) Radha Raman Pandey et al.   MOLECULAR CELL

A model for transmission of the H3K27me3 epigenetic mark

(2008) Klaus H. Hansen et al.   NATURE CELL BIOLOGY

De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

(2008) Silvina Epsztejn-Litman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome

(2008) J. Zhao et al.   SCIENCE