Class 3 semaphorins modulate the invasive capacity of rheumatoid arthritis fibroblast-like synoviocytes

Semaphorin-3F suppresses the stemness of colorectal cancer cells by inactivating Rac1

(2015) Jun Rao et al.   CANCER LETTERS

Protein Inhibitor of Activated STAT3 Regulates Migration, Invasion, and Activation of Fibroblast-like Synoviocytes in Rheumatoid Arthritis

(2015) Minxi Lao et al.   JOURNAL OF IMMUNOLOGY

SEMA3F prevents metastasis of colorectal cancer by PI3K-AKT-dependent down-regulation of the ASCL2-CXCR4 axis

(2015) Zhi-hang Zhou et al.   JOURNAL OF PATHOLOGY

The axon guidance molecule semaphorin 3F is a negative regulator of tumor progression and proliferation in ileal neuroendocrine tumors

(2015) Julien Bollard et al.   Oncotarget

Expression of class 3 semaphorins and their receptors in human breast neoplasia

(2015) Carolyn A Staton et al.   HISTOPATHOLOGY

Tumor Suppressor Function of the SEMA3B Gene in Human Lung and Renal Cancers

(2015) Vitaly I. Loginov et al.   PLoS One

Phosphoinositide 3-Kinase   Regulates Migration and Invasion of Synoviocytes in Rheumatoid Arthritis

(2014) B. Bartok et al.   JOURNAL OF IMMUNOLOGY

Semaphorins and plexins as therapeutic targets

(2014) Thomas Worzfeld et al.   NATURE REVIEWS DRUG DISCOVERY

Local Synovial Engagement of Angiogenic TIE-2 Is Associated With the Development of Persistent Erosive Rheumatoid Arthritis in Patients With Early Arthritis

(2013) Marleen G. H. van de Sande et al.   ARTHRITIS AND RHEUMATISM

Decreased Semaphorin3A expression correlates with disease activity and histological features of rheumatoid arthritis

(2013) Shu Takagawa et al.   BMC MUSCULOSKELETAL DISORDERS

Class 3 semaphorins as a therapeutic target

(2012) Yoshio Goshima et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice

(2012) Federica Maione et al.   JOURNAL OF CLINICAL INVESTIGATION

Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors

(2012) Nunzio Bottini et al.   Nature Reviews Rheumatology

The Features of the Synovium in Early Rheumatoid Arthritis According to the 2010 ACR/EULAR Classification Criteria

(2012) Marleen G. H. van de Sande et al.   PLoS One

Intimal lining layer macrophages but not synovial sublining macrophages display an IL-10 polarized-like phenotype in chronic synovitis

(2012) Carmen A Ambarus et al.   ARTHRITIS RESEARCH & THERAPY

Receptor complexes for each of the Class 3 Semaphorins

(2012) Anil Sharma et al.   Frontiers in Cellular Neuroscience

Selective involvement of ERK and JNK mitogen-activated protein kinases in early rheumatoid arthritis (1987 ACR criteria compared to 2010 ACR/EULAR criteria): a prospective study aimed at identification of diagnostic and prognostic biomarkers as well as therapeutic targets

(2011) Daphne de Launay et al.   ANNALS OF THE RHEUMATIC DISEASES

Systematic validation of specific phenotypic markers for in vitro polarized human macrophages

(2011) C.A. Ambarus et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Progesterone and 1,25-Dihydroxyvitamin D3 Inhibit Endometrial Cancer Cell Growth by Upregulating Semaphorin 3B and Semaphorin 3F

(2011) H. Nguyen et al.   MOLECULAR CANCER RESEARCH

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Presence of lymphocyte aggregates in the synovium of patients with early arthritis in relationship to diagnosis and outcome: is it a constant feature over time?

(2010) M. G. H. van de Sande et al.   ANNALS OF THE RHEUMATIC DISEASES

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) Daniel Aletaha et al.   ARTHRITIS AND RHEUMATISM

The Neuroimmune Semaphorin-3A Reduces Inflammation and Progression of Experimental Autoimmune Arthritis

(2010) A. Catalano   JOURNAL OF IMMUNOLOGY

Akt activity protects rheumatoid synovial fibroblasts from Fas-induced apoptosis by inhibition of Bid cleavage

(2010) Samuel García et al.   ARTHRITIS RESEARCH & THERAPY

A Rac1 inhibitory peptide suppresses antibody production and paw swelling in the murine collagen-induced arthritis model of rheumatoid arthritis

(2010) Joana RF Abreu et al.   ARTHRITIS RESEARCH & THERAPY

Role of Class 3 Semaphorins and Their Receptors in Tumor Growth and Angiogenesis

(2009) P. Gaur et al.   CLINICAL CANCER RESEARCH

Synovial fibroblasts spread rheumatoid arthritis to unaffected joints

(2009) Stephanie Lefèvre et al.   NATURE MEDICINE

Semaphorin 3B Inhibits the Phosphatidylinositol 3-Kinase/Akt Pathway through Neuropilin-1 in Lung and Breast Cancer Cells

(2008) E. Castro-Rivera et al.   CANCER RESEARCH

Semaphorin-3B Is an Angiogenesis Inhibitor That Is Inactivated by Furin-Like Pro-Protein Convertases

(2008) A. Varshavsky et al.   CANCER RESEARCH

The many faces of semaphorins: from development to pathology

(2008) L. Roth et al.   CELLULAR AND MOLECULAR LIFE SCIENCES