Transthyretin variants with improved inhibition of β-amyloid aggregation

Transthyretin-Derived Peptides as β-Amyloid Inhibitors

(2014) Patricia Y. Cho et al.   ACS Chemical Neuroscience

Evaluation of nanoparticle tracking for characterization of fibrillar protein aggregates

(2014) Dennis T. Yang et al.   AICHE JOURNAL

Immunotherapy for Alzheimer's disease

(2014) Thomas Wisniewski et al.   BIOCHEMICAL PHARMACOLOGY

Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease

(2014) Cassia R. Overk et al.   BIOCHEMICAL PHARMACOLOGY

Online Registry for Mutations in Hereditary Amyloidosis Including Nomenclature Recommendations

(2014) Dorota M. Rowczenio et al.   HUMAN MUTATION

Delineation of Concentration Ranges and Longitudinal Changes of Human Plasma Protein Variants

(2014) Olgica Trenchevska et al.   PLoS One

Age-Related Oxidative Modifications of Transthyretin Modulate Its Amyloidogenicity

(2013) Lei Zhao et al.   BIOCHEMISTRY

Transthyretin as both a Sensor and a Scavenger of β-Amyloid Oligomers

(2013) Dennis T. Yang et al.   BIOCHEMISTRY

News from the Protein Mutability Landscape

(2013) Maximilian Hecht et al.   JOURNAL OF MOLECULAR BIOLOGY

Mechanisms of Transthyretin Inhibition of  -Amyloid Aggregation In Vitro

(2013) X. Li et al.   JOURNAL OF NEUROSCIENCE

Characterization and stability of transthyretin isoforms in cerebrospinal fluid examined by immunoprecipitation and high-resolution mass spectrometry of intact protein

(2012) Keld Poulsen et al.   METHODS

Identification of beta-amyloid-binding sites on transthyretin

(2012) J. Du et al.   PROTEIN ENGINEERING DESIGN & SELECTION

A partially folded structure of amyloid-beta(1–40) in an aqueous environment

(2011) Subramanian Vivekanandan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Quantifying the Kinetic Stability of Hyperstable Proteins via Time-Dependent SDS Trapping

(2011) Ke Xia et al.   BIOCHEMISTRY

The Japanese Mutant Aβ (ΔE22-Aβ1−39) Forms Fibrils Instantaneously, with Low-Thioflavin T Fluorescence: Seeding of Wild-Type Aβ1−40into Atypical Fibrils by ΔE22-Aβ1−39

(2011) Adam L. Cloe et al.   BIOCHEMISTRY

Experimentally Derived Structural Constraints for Amyloid Fibrils of Wild-Type Transthyretin

(2011) David A. Bateman et al.   BIOPHYSICAL JOURNAL

Neuronal Production of Transthyretin in Human and Murine Alzheimer's Disease: Is It Protective?

(2011) X. Li et al.   JOURNAL OF NEUROSCIENCE

Familial amyloid polyneuropathy

(2011) Violaine Planté-Bordeneuve et al.   LANCET NEUROLOGY

KFC2: A knowledge-based hot spot prediction method based on interface solvation, atomic density, and plasticity features

(2011) Xiaolei Zhu et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Mass spectrometric immunoassay for quantitative determination of transthyretin and its variants

(2011) Olgica Trenchevska et al.   PROTEOMICS

Characterization of the Interaction of β-Amyloid with Transthyretin Monomers and Tetramers

(2010) Jiali Du et al.   BIOCHEMISTRY

Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates

(2010) Vasco Filipe et al.   PHARMACEUTICAL RESEARCH

Differential modification of Cys10 alters transthyretin's effect on beta-amyloid aggregation and toxicity

(2009) L. Liu et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Quantification of the Thermodynamically Linked Quaternary and Tertiary Structural Stabilities of Transthyretin and Its Disease-Associated Variants: The Relationship between Stability and Amyloidosis†

(2008) Amy R. Hurshman Babbes et al.   BIOCHEMISTRY

Transthyretin binding to A-Beta peptide - Impact on A-Beta fibrillogenesis and toxicity

(2008) R. Costa et al.   FEBS LETTERS

The Modulation of Transthyretin Tetramer Stability by Cysteine 10 Adducts and the Drug Diflunisal

(2008) Jonathan S. Kingsbury et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insight into pH-Induced Conformational Changes within the Native Human Transthyretin Tetramer

(2008) Satheesh K. Palaninathan et al.   JOURNAL OF MOLECULAR BIOLOGY

Extrinsic Fluorescent Dyes as Tools for Protein Characterization

(2008) Andrea Hawe et al.   PHARMACEUTICAL RESEARCH

Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of A  toxicity

(2008) J. N. Buxbaum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA