Identification of thioredoxin-interacting protein (TXNIP) as a downstream target for IGF1 action

A novel indication of thioredoxin-interacting protein as a tumor suppressor gene in malignant glioma

(2017) Pengxing Zhang et al.   Oncology Letters

Phosphorylation of TXNIP by AKT Mediates Acute Influx of Glucose in Response to Insulin

(2017) Althea N. Waldhart et al.   Cell Reports

Identification of signaling pathways associated with cancer protection in Laron syndrome

(2016) Lena Lapkina-Gendler et al.   ENDOCRINE-RELATED CANCER

2-Deoxyglucose induces the expression of thioredoxin interacting protein (TXNIP) by increasing O-GlcNAcylation – Implications for targeting the Warburg effect in cancer cells

(2015) Shin Yee Hong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Thioredoxin/Txnip: Redoxisome, as a Redox Switch for the Pathogenesis of Diseases

(2014) Eiji Yoshihara et al.   Frontiers in Immunology

Critical role of TXNIP in oxidative stress, DNA damage and retinal pericyte apoptosis under high glucose: Implications for diabetic retinopathy

(2013) Takhellambam S. Devi et al.   EXPERIMENTAL CELL RESEARCH

Thioredoxin-interacting Protein Mediates High Glucose-induced Reactive Oxygen Species Generation by Mitochondria and the NADPH Oxidase, Nox4, in Mesangial Cells

(2013) Anu Shah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serum IGF-1 Is Insufficient to Restore Skeletal Size in the Total Absence of the Growth Hormone Receptor

(2013) Yingjie Wu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Insulin-Like Growth Factor 1 Physiology

(2012) Shoshana Yakar et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Roles of thioredoxin binding protein (TXNIP) in oxidative stress, apoptosis and cancer

(2012) Jianbiao Zhou et al.   MITOCHONDRION

Congenital IGF1 deficiency tends to confer protection against post-natal development of malignancies

(2011) Rachel Steuerman et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Nutrient-Sensing Hypothalamic TXNIP Links Nutrient Excess to Energy Imbalance in Mice

(2011) C. Blouet et al.   JOURNAL OF NEUROSCIENCE

Tumor suppressors govern insulin-like growth factor signaling pathways: implications in metabolism and cancer

(2011) H Werner   ONCOGENE

Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans

(2011) J. Guevara-Aguirre et al.   Science Translational Medicine

Lactic Acidosis Triggers Starvation Response with Paradoxical Induction of TXNIP through MondoA

(2010) Julia Ling-Yu Chen et al.   PLoS Genetics

High-Efficient FLPo Deleter Mice in C57BL/6J Background

(2009) Yingjie Wu et al.   PLoS One

IGF signaling defects as causes of growth failure and IUGR

(2008) Jürgen Klammt et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM