Modeling combination therapy for breast cancer with BET and immune checkpoint inhibitors
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Title
Modeling combination therapy for breast cancer with BET and immune checkpoint inhibitors
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 115, Issue 21, Pages 5534-5539
Publisher
Proceedings of the National Academy of Sciences
Online
2018-05-08
DOI
10.1073/pnas.1721559115
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- (2017) Takao Fujisawa et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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- (2017) Fraser Aird et al. eLife
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- (2016) Elizabeth I. Buchbinder et al. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
- Immune-related adverse events with immune checkpoint blockade: a comprehensive review
- (2016) J.M. Michot et al. EUROPEAN JOURNAL OF CANCER
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- (2016) Ningning Niu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2016) Hengrui Zhu et al. Cell Reports
- Serum uPAR as Biomarker in Breast Cancer Recurrence: A Mathematical Model
- (2016) Wenrui Hao et al. PLoS One
- Immune Checkpoint Blockade in Cancer Therapy
- (2015) Michael A. Postow et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2014) C. U. Blank et al. INTERNATIONAL IMMUNOLOGY
- The Mechanisms behind the Therapeutic Activity of BET Bromodomain Inhibition
- (2014) Junwei Shi et al. MOLECULAR CELL
- Targeting bromodomains: epigenetic readers of lysine acetylation
- (2014) Panagis Filippakopoulos et al. NATURE REVIEWS DRUG DISCOVERY
- NF-κB Functions in Tumor Initiation by Suppressing the Surveillance of Both Innate and Adaptive Immune Cells
- (2014) David J. Wang et al. Cell Reports
- Tumor-Associated Macrophages as Major Players in the Tumor Microenvironment
- (2014) Theerawut Chanmee et al. Cancers
- Insights into the Transforming Growth Factor-β Signaling Pathway in Cutaneous Melanoma
- (2013) Carole Yolande Perrot et al. Annals of Dermatology
- Myeloid-derived suppressor cells in breast cancer
- (2013) Joseph Markowitz et al. BREAST CANCER RESEARCH AND TREATMENT
- The role of tumor-associated macrophages in breast cancer progression
- (2013) ELIAS OBEID et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Treg and CTLA-4: Two intertwining pathways to immune tolerance
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- BET Protein Function Is Required for Inflammation: Brd2 Genetic Disruption and BET Inhibitor JQ1 Impair Mouse Macrophage Inflammatory Responses
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- RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain
- (2013) S. Picaud et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dendritic Cells in the Cancer Microenvironment
- (2013) Yang Ma et al. Journal of Cancer
- A Mathematical Model of the Enhancement of Tumor Vaccine Efficacy by Immunotherapy
- (2012) Shelby Wilson et al. BULLETIN OF MATHEMATICAL BIOLOGY
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- (2012) Barbara Szomolay et al. JOURNAL OF THEORETICAL BIOLOGY
- BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
- (2011) Jake E. Delmore et al. CELL
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- (2011) Xin Chen et al. FEBS LETTERS
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- (2011) J. A. Mertz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2008) B. Huang et al. MOLECULAR AND CELLULAR BIOLOGY
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