TMEM59 potentiates Wnt signaling by promoting signalosome formation
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Title
TMEM59 potentiates Wnt signaling by promoting signalosome formation
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 115, Issue 17, Pages E3996-E4005
Publisher
Proceedings of the National Academy of Sciences
Online
2018-04-10
DOI
10.1073/pnas.1721321115
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Note: Only part of the references are listed.- Multiprotein complexes governing Wnt signal transduction
- (2018) Melissa Gammons et al. CURRENT OPINION IN CELL BIOLOGY
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- (2016) Dheeraj Bhavanasi et al. JOURNAL OF CLINICAL INVESTIGATION
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- Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled
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- (2016) Qiuyang Zheng et al. MOLECULAR NEUROBIOLOGY
- Visualization of a short-range Wnt gradient in the intestinal stem-cell niche
- (2016) Henner F. Farin et al. NATURE
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- (2016) Babita Madan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine
- (2015) Aurélie Ladang et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2015) Matthias Zebisch et al. JOURNAL OF STRUCTURAL BIOLOGY
- YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response
- (2014) Luca Azzolin et al. CELL
- Signalosome assembly by domains undergoing dynamic head-to-tail polymerization
- (2014) Mariann Bienz TRENDS IN BIOCHEMICAL SCIENCES
- Overexpression of DCF1 inhibits glioma through destruction of mitochondria and activation of apoptosis pathway
- (2014) Yuqiong Xie et al. Scientific Reports
- Wnt signalling induces accumulation of phosphorylated -catenin in two distinct cytosolic complexes
- (2014) J. P. Gerlach et al. Open Biology
- TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3
- (2013) Emilio Boada-Romero et al. EMBO JOURNAL
- The structural basis of R-spondin recognition by LGR5 and RNF43
- (2013) P.-H. Chen et al. GENES & DEVELOPMENT
- Clathrin and AP2 are required for PtdIns(4,5)P2-mediated formation of LRP6 signalosomes
- (2013) Ingyu Kim et al. JOURNAL OF CELL BIOLOGY
- Structure of the human smoothened receptor bound to an antitumour agent
- (2013) Chong Wang et al. NATURE
- Structures of Wnt-Antagonist ZNRF3 and Its Complex with R-Spondin 1 and Implications for Signaling
- (2013) Weng Chuan Peng et al. PLoS One
- ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
- (2012) Huai-Xiang Hao et al. NATURE
- Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors
- (2012) Bon-Kyoung Koo et al. NATURE
- Wnt/ -catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled
- (2012) D. V. F. Tauriello et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural Basis of Wnt Recognition by Frizzled
- (2012) C. Y. Janda et al. SCIENCE
- Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis
- (2011) Brady K Atwood et al. BMC GENOMICS
- Rack1 is required for Vangl2 membrane localization and planar cell polarity signaling while attenuating canonical Wnt activity
- (2011) S. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt
- (2010) Akiko Mukai et al. EMBO JOURNAL
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- (2010) Sylvia Ullrich et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- LRP6 is internalized by Dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse
- (2010) H. Sakane et al. JOURNAL OF CELL SCIENCE
- The EDD E3 ubiquitin ligase ubiquitinates and up-regulates β-catenin
- (2010) Avital Hay-Koren et al. MOLECULAR BIOLOGY OF THE CELL
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- (2010) Daniele V.F. Tauriello et al. MOLECULAR CELL
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- (2008) Vladimir L Katanaev et al. EMBO JOURNAL
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- (2008) C. S. Cselenyi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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