Age-related endolysosome dysfunction in the rat urothelium

Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseases

(2018) Chao Wang et al.   CURRENT OPINION IN NEUROBIOLOGY

Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease

(2017) Lena F. Burbulla et al.   SCIENCE

The crucial impact of lysosomes in aging and longevity

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Regulation of lysosomal dynamics and autophagy by CTSB/cathepsin B

(2016) Si Ming Man et al.   Autophagy

Endolysosomes Are the Principal Intracellular Sites of Acid Hydrolase Activity

(2016) Nicholas A. Bright et al.   CURRENT BIOLOGY

The lysosome as a command-and-control center for cellular metabolism

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The Autophagy–Lysosomal Pathway in Neurodegeneration: A TFEB Perspective

(2016) Heidi Martini-Stoica et al.   TRENDS IN NEUROSCIENCES

The urothelium: Anatomy, review of the literature, perspectives for veterinary medicine

(2015) S. Arrighi   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Lysosomal Physiology

(2015) Haoxing Xu et al.   Annual Review of Physiology

A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion

(2015) Yuxuan Miao et al.   CELL

ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes

(2015) Jiajie Diao et al.   NATURE

Lysosomal enzyme cathepsin B enhances the aggregate forming activity of exogenous α-synuclein fibrils

(2015) Atsushi Tsujimura et al.   NEUROBIOLOGY OF DISEASE

Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer’s disease amyloid plaques

(2015) Swetha Gowrishankar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans

(2015) A. Folick et al.   SCIENCE

Cathepsin Inhibition-Induced Lysosomal Dysfunction Enhances Pancreatic Beta-Cell Apoptosis in High Glucose

(2015) Minjeong Jung et al.   PLoS One

The role of protein clearance mechanisms in organismal ageing and age-related diseases

(2014) David Vilchez et al.   Nature Communications

Lysosomal storage diseases—the horizon expands

(2013) Rose-Mary Naaman Boustany   Nature Reviews Neurology

Urothelial Signaling

(2013) Lori Birder et al.   PHYSIOLOGICAL REVIEWS

Oxidative Status and Lipofuscin Accumulation in Urothelial Cells of Bladder in Aging Mice

(2013) Martina Perše et al.   PLoS One

Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells

(2012) Katrijn Coen et al.   JOURNAL OF CELL BIOLOGY

Atg16L1 deficiency confers protection from uropathogenic Escherichia coli infection in vivo

(2012) C. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multivesicular Body Morphogenesis

(2011) Phyllis I. Hanson et al.   Annual Review of Cell and Developmental Biology

Lysosomal Acidification Mechanisms

(2011) Joseph A. Mindell   Annual Review of Physiology

Reduction of mutant huntingtin accumulation and toxicity by lysosomal cathepsins D and B in neurons

(2011) Qiuli Liang et al.   Molecular Neurodegeneration

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

Exploring the link between glucocerebrosidase mutations and parkinsonism

(2011) Wendy Westbroek et al.   TRENDS IN MOLECULAR MEDICINE

Compensatory endocytosis in bladder umbrella cells occurs through an integrin-regulated and RhoA- and dynamin-dependent pathway

(2010) Puneet Khandelwal et al.   EMBO JOURNAL

Involvement of Vps33a in the Fusion of Uroplakin-Degrading Multivesicular Bodies with Lysosomes

(2009) Xuemei Guo et al.   TRAFFIC

Autophagy: Basic Principles and Relevance to Disease

(2008) Mondira Kundu et al.   Annual Review of Pathology-Mechanisms of Disease