A FRET-based biosensor for measuring Gα13 activation in single cells

Potentiation of receptor responses induced by prolonged binding of Gα13 and leukemia-associated RhoGEF

(2017) Eva-Lisa Bodmann et al.   FASEB JOURNAL

Characterization of a spectrally diverse set of fluorescent proteins as FRET acceptors for mTurquoise2

(2017) Marieke Mastop et al.   Scientific Reports

Spatiotemporal analysis of RhoA/B/C activation in primary human endothelial cells

(2016) Nathalie R. Reinhard et al.   Scientific Reports

A New Generation of FRET Sensors for Robust Measurement of Gαi1, Gαi2 and Gαi3 Activation Kinetics in Single Cells

(2016) Jakobus van Unen et al.   PLoS One

Fast and high resolution single-cell BRET imaging

(2016) Elise Goyet et al.   Scientific Reports

Kinetics of recruitment and allosteric activation of ARHGEF25 isoforms by the heterotrimeric G-protein Gαq

(2016) Jakobus van Unen et al.   Scientific Reports

Single-cell Analysis of G-protein Signal Transduction

(2015) Terri Clister et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Versatile Toolkit to Produce Sensitive FRET Biosensors to Visualize Signaling in Time and Space

(2013) R. D. Fritz et al.   Science Signaling

G 13 -Mediated Signaling Pathway Is Required for Pressure Overload–Induced Cardiac Remodeling and Heart Failure

(2012) Mikito Takefuji et al.   CIRCULATION

Deciphering biased-agonism complexity reveals a new active AT1 receptor entity

(2012) Aude Saulière et al.   Nature Chemical Biology

TGFα shedding assay: an accurate and versatile method for detecting GPCR activation

(2012) Asuka Inoue et al.   NATURE METHODS

Real-time visualization of heterotrimeric G protein Gq activation in living cells

(2011) Merel JW Adjobo-Hermans et al.   BMC BIOLOGY

Quantitative Co-Expression of Proteins at the Single Cell Level – Application to a Multimeric FRET Sensor

(2011) Joachim Goedhart et al.   PLoS One

Use of the GTPγS ([35S]GTPγS and Eu-GTPγS) binding assay for analysis of ligand potency and efficacy at G protein-coupled receptors

(2010) Philip G. Strange   BRITISH JOURNAL OF PHARMACOLOGY

Differential association modes of the thrombin receptor PAR1 with Gαi1, Gα12, and β-arrestin 1

(2010) Mohammed Akli Ayoub et al.   FASEB JOURNAL

Regulation of RhoGEF proteins by G12/13-coupled receptors

(2009) Sandra Siehler   BRITISH JOURNAL OF PHARMACOLOGY

Activation of Rho and Rho-Associated Kinase by GPR54 and KiSS1 Metastasis Suppressor Gene Product Induces Changes of Cell Morphology and Contributes to Apoptosis

(2009) J.-M. Navenot et al.   MOLECULAR PHARMACOLOGY

Structure and Function of Heterotrimeric G Protein-Regulated Rho Guanine Nucleotide Exchange Factors

(2009) M. Aittaleb et al.   MOLECULAR PHARMACOLOGY

Reversible translocation of p115-RhoGEF by G12/13-coupled receptors

(2008) Bruno H. Meyer et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

G12/G13-mediated signalling in mammalian physiology and disease

(2008) Thomas Worzfeld et al.   TRENDS IN PHARMACOLOGICAL SCIENCES