Differential role of MyD88 and TRIF signaling in myeloid cells in the pathogenesis of autoimmune diabetes

The importance of the Non Obese Diabetic (NOD) mouse model in autoimmune diabetes

(2016) James A. Pearson et al.   JOURNAL OF AUTOIMMUNITY

The role of the innate immune system in destruction of pancreatic beta cells in NOD mice and humans with type I diabetes

(2016) Ningwen Tai et al.   JOURNAL OF AUTOIMMUNITY

IDO-Expressing Fibroblasts Protect Islet Beta Cells From Immunological Attack and Reverse Hyperglycemia in Non-Obese Diabetic Mice

(2016) Yun Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

TLR-independent anti-inflammatory function of intestinal epithelial TRAF6 signalling prevents DSS-induced colitis in mice

(2015) Katerina Vlantis et al.   GUT

Microbiota regulates type 1 diabetes through Toll-like receptors

(2015) Michael P. Burrows et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

(2014) Marius Dannappel et al.   NATURE

High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9–TRIF pathway

(2013) Claudia Volpi et al.   Nature Communications

Indoleamine 2,3-Dioxygenase and Dendritic Cell Tolerogenicity

(2012) Jamie L Harden et al.   IMMUNOLOGICAL INVESTIGATIONS

Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes

(2012) Julien Diana et al.   NATURE MEDICINE

Mechanism Underlying Defective Interferon Gamma-Induced IDO Expression in Non-obese Diabetic Mouse Fibroblasts

(2012) Azadeh Hosseini-Tabatabaei et al.   PLoS One

Activation of the noncanonical NF- B pathway by HIV controls a dendritic cell immunoregulatory phenotype

(2012) O. Manches et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase

(2012) B. Ravishankar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myeloid differentiation primary response protein 88 blockade upregulates indoleamine 2,3-dioxygenase expression in rheumatoid synovial fibroblasts

(2011) Mi-Kyung Park et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Physiologic Control of IDO Competence in Splenic Dendritic Cells

(2011) B. Baban et al.   JOURNAL OF IMMUNOLOGY

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

(2011) Maria T Pallotta et al.   NATURE IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Role of the TLR signaling molecule TRIF in β-cell function and glucose homeostasis

(2010) Meredith J. H. Hutton et al.   Islets

IDO Mediates TLR9-Driven Protection from Experimental Autoimmune Diabetes

(2009) F. Fallarino et al.   JOURNAL OF IMMUNOLOGY

A protocol for islet isolation from mouse pancreas

(2009) Dong-Sheng Li et al.   Nature Protocols

The Toll-Like Receptor Signaling Molecule Myd88 Contributes to Pancreatic Beta-Cell Homeostasis in Response to Injury

(2009) Paul L. Bollyky et al.   PLoS One

IRAK-4- and MyD88-Dependent Pathways Are Essential for the Removal of Developing Autoreactive B Cells in Humans

(2008) Isabelle Isnardi et al.   IMMUNITY

MyD88 Negatively Controls Hypergammaglobulinemia with Autoantibody Production during Bacterial Infection

(2008) A. Woods et al.   INFECTION AND IMMUNITY

Curcumin Suppresses the Induction of Indoleamine 2,3-Dioxygenase by Blocking the Janus-activated Kinase-Protein Kinase Cδ-STAT1 Signaling Pathway in Interferon-γ-stimulated Murine Dendritic Cells

(2008) Young-Il Jeong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice

(2008) Beichu Guo et al.   JOURNAL OF CLINICAL INVESTIGATION

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

(2008) Li Wen et al.   NATURE