IDO-Expressing Fibroblasts Protect Islet Beta Cells From Immunological Attack and Reverse Hyperglycemia in Non-Obese Diabetic Mice

Immunoprotection and Functional Improvement of Allogeneic Islets in Diabetic Mice, Using a Stable Indoleamine 2,3-Dioxygenase Producing Scaffold

(2015) Azadeh Hosseini-Tabatabaei et al.   TRANSPLANTATION

Combination Therapy With an Anti–IL-1β Antibody and GAD65 DNA Vaccine Can Reverse Recent-Onset Diabetes in the RIP-GP Mouse Model

(2014) Philippe P. Pagni et al.   DIABETES

Treatment of new onset type 1 diabetes with teplizumab: successes and pitfalls in development

(2014) Nalini K Vudattu et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The Indoleamine 2,3-Dioxygenase Pathway Is Essential for Human Plasmacytoid Dendritic Cell-Induced Adaptive T Regulatory Cell Generation

(2014) W. Chen et al.   JOURNAL OF IMMUNOLOGY

Indoleamine 2,3 dioxygenase contributes to transferable tolerance in rat red blood cell inducible model of experimental autoimmune haemolytic anaemia

(2013) L. N. Dahal et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

IDO expressing fibroblasts promote the expansion of antigen specific regulatory T cells

(2013) Terry-Ann Curran et al.   IMMUNOBIOLOGY

Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials

(2013) Antoinette Moran et al.   LANCET

Immuno-Regulatory Function of Indoleamine 2,3 Dioxygenase through Modulation of Innate Immune Responses

(2013) Malihe-Sadat Poormasjedi-Meibod et al.   PLoS One

The pancreatic β cell and type 1 diabetes: innocent bystander or active participant?

(2013) Scott A. Soleimanpour et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Using an Ancient Tool for Igniting and Propagating Immune Tolerance: IDO as an Inducer and Amplifier of Regulatory T Cell Functions

(2012) F. Fallarino et al.   CURRENT MEDICINAL CHEMISTRY

Crystal Structure of Human RANKL Complexed with Its Decoy Receptor Osteoprotegerin

(2012) X. Luan et al.   JOURNAL OF IMMUNOLOGY

Toll-like receptors, the NLRP3 inflammasome and interleukin-1β in the development and progression of type 1 diabetes

(2012) Ellen K. Grishman et al.   PEDIATRIC RESEARCH

Indoleamine, 2-3 Dioxygenase Activity Could Be an Early Marker of Graft Rejection in Heart Transplantation

(2012) N. Suarez-Fuentetaja et al.   TRANSPLANTATION PROCEEDINGS

Synergistic Reversal of Type 1 Diabetes in NOD Mice With Anti-CD3 and Interleukin-1 Blockade: Evidence of Improved Immune Regulation

(2011) V. Ablamunits et al.   DIABETES

Expansion of Th17 Cells and Functional Defects in T Regulatory Cells Are Key Features of the Pancreatic Lymph Nodes in Patients With Type 1 Diabetes

(2011) Alessandra Ferraro et al.   DIABETES

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

(2011) Maria T Pallotta et al.   NATURE IMMUNOLOGY

Indoleamine 2,3-dioxygenase specific, cytotoxic T cells as immune regulators

(2010) R. B. Sorensen et al.   BLOOD

Local Expression of Indoleamine 2,3 Dioxygenase in Syngeneic Fibroblasts Significantly Prolongs Survival of an Engineered Three-Dimensional Islet Allograft

(2010) R. B. Jalili et al.   DIABETES

Fibroblast populated collagen matrix promotes islet survival and reduces the number of islets required for diabetes reversal

(2010) Reza B. Jalili et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cutting Edge: Increased IL-17-Secreting T Cells in Children with New-Onset Type 1 Diabetes

(2010) A. K. Marwaha et al.   JOURNAL OF IMMUNOLOGY

IL-17 Immunity in Human Type 1 Diabetes

(2010) J. Honkanen et al.   JOURNAL OF IMMUNOLOGY

IDO Upregulates Regulatory T Cells via Tryptophan Catabolite and Suppresses Encephalitogenic T Cell Responses in Experimental Autoimmune Encephalomyelitis

(2010) Y. Yan et al.   JOURNAL OF IMMUNOLOGY

Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells

(2009) Natalia Martin-Orozco et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-1β receptor blockade protects islets against pro-inflammatory cytokine induced necrosis and apoptosis

(2009) Alice Schwarznau et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone

(2009) Francesca Fallarino et al.   JOURNAL OF EXPERIMENTAL MEDICINE

 -Cell Mass and Type 1 Diabetes: Going, Going, Gone?

(2008) E. Akirav et al.   DIABETES

HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase–dependent mechanism

(2008) Olivier Manches et al.   JOURNAL OF CLINICAL INVESTIGATION

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease

(2008) Luigina Romani et al.   NATURE

Short-term anti-CD25 monoclonal antibody treatment and neogenetic CD4+CD25high regulatory T cells in kidney transplantation

(2008) Zhen Wang et al.   TRANSPLANT IMMUNOLOGY