High content screening of patient-derived cell lines highlights the potential of non-standard chemotherapeutic agents for the treatment of glioblastoma

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

MET inhibition overcomes radiation resistance of glioblastoma stem‐like cells

(2016) Francesca De Bacco et al.   EMBO Molecular Medicine

A phase II trial evaluating the effects and intra-tumoral penetration of bortezomib in patients with recurrent malignant gliomas

(2016) Jeffrey J. Raizer et al.   JOURNAL OF NEURO-ONCOLOGY

Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma

(2016) Theophilos Tzaridis et al.   Oncotarget

A phase II trial of tamoxifen and bortezomib in patients with recurrent malignant gliomas

(2015) Yazmín Odia et al.   JOURNAL OF NEURO-ONCOLOGY

Survival outcomes and safety of carmustine wafers in the treatment of high-grade gliomas: a meta-analysis

(2015) Sajeel A. Chowdhary et al.   JOURNAL OF NEURO-ONCOLOGY

Convection-enhanced delivery for the treatment of glioblastoma

(2015) M. A. Vogelbaum et al.   NEURO-ONCOLOGY

High-Throughput Screening of Patient-Derived Cultures Reveals Potential for Precision Medicine in Glioblastoma

(2015) Christine E. Quartararo et al.   ACS Medicinal Chemistry Letters

Novel chemical library screen identifies naturally occurring plant products that specifically disrupt glioblastoma-endothelial cell interactions

(2015) Rajarshi Sengupta et al.   Oncotarget

EGFRAmplification and Glioblastoma Stem-Like Cells

(2015) Katrin Liffers et al.   Stem Cells International

High-dose chemotherapy (HDCT) with auto-SCT in children with atypical teratoid/rhabdoid tumors (AT/RT): a report from the European Rhabdoid Registry (EU-RHAB)

(2014) M Benesch et al.   BONE MARROW TRANSPLANTATION

Glioblastoma stem-like cells: at the root of tumor recurrence and a therapeutic target

(2014) Melanie Jackson et al.   CARCINOGENESIS

Effects of temozolomide (TMZ) on the expression and interaction of heat shock proteins (HSPs) and DNA repair proteins in human malignant glioma cells

(2014) Gisela Natalia Castro et al.   CELL STRESS & CHAPERONES

Novel anti-glioblastoma agents and therapeutic combinations identified from a collection of FDA approved drugs

(2014) Pengfei Jiang et al.   Journal of Translational Medicine

Systematic review and meta-analysis of temozolomide in animal models of glioma: was clinical efficacy predicted?

(2013) T C Hirst et al.   BRITISH JOURNAL OF CANCER

Proteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells' VEGF production and angiogenesis

(2013) Daniela A. Bota et al.   JOURNAL OF NEUROSURGERY

Myeloid/Microglial Driven Autologous Hematopoietic Stem Cell Gene Therapy Corrects a Neuronopathic Lysosomal Disease

(2013) Ana Sergijenko et al.   MOLECULAR THERAPY

High-Throughput 3D Screening Reveals Differences in Drug Sensitivities between Culture Models of JIMT1 Breast Cancer Cells

(2013) Vesa Hongisto et al.   PLoS One

3D Organotypic Cultures of Human HepaRG Cells: A Tool for In Vitro Toxicity Studies

(2013) Patrina Gunness et al.   TOXICOLOGICAL SCIENCES

The BH3 mimetic ABT-737 increases treatment efficiency of paclitaxel against hepatoblastoma

(2011) Justus Lieber et al.   BMC CANCER

Tissue concentration of systemically administered antineoplastic agents in human brain tumors

(2011) Marshall W. Pitz et al.   JOURNAL OF NEURO-ONCOLOGY

Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma: a north central cancer treatment group study

(2011) B. B. Friday et al.   NEURO-ONCOLOGY

Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells

(2011) H. Wakimoto et al.   NEURO-ONCOLOGY

Functional Drug Screening Assay Reveals Potential Glioma Therapeutics

(2010) Christian E. Badr et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Bioengineered 3D platform to explore cell–ECM interactions and drug resistance of epithelial ovarian cancer cells

(2010) Daniela Loessner et al.   BIOMATERIALS

Scale to Predict Survival After Surgery for Recurrent Glioblastoma Multiforme

(2010) John K. Park et al.   JOURNAL OF CLINICAL ONCOLOGY

Hydrogels as extracellular matrix mimics for 3D cell culture

(2009) Mark W. Tibbitt et al.   BIOTECHNOLOGY AND BIOENGINEERING

Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens

(2009) Steven M. Pollard et al.   Cell Stem Cell

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

A New Model for Prediction of Drug Distribution in Tumor and Normal Tissues: Pharmacokinetics of Temozolomide in Glioma Patients

(2008) L. Rosso et al.   CANCER RESEARCH

Treatment of recurrent glioblastoma: can local delivery of mitoxantrone improve survival?

(2008) Amerigo Boiardi et al.   JOURNAL OF NEURO-ONCOLOGY

Antitumor Effects of Doxorubicin Followed by Zoledronic Acid in a Mouse Model of Breast Cancer

(2008) P. D. Ottewell et al.   JNCI-Journal of the National Cancer Institute

Comparison of 3D and 2D tumor models reveals enhanced HER2 activation in 3D associated with an increased response to trastuzumab

(2008) M Pickl et al.   ONCOGENE