Design, synthesis, DFT, docking studies and ADME prediction of some new coumarinyl linked pyrazolylthiazoles: Potential standalone or adjuvant antimicrobial agents

New arylpyrazoline-coumarins: Synthesis and anti-inflammatory activity

(2017) Liu Zeng Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, antitumor activity and CDK1 inhibiton of new thiazole nortopsentin analogues

(2017) Barbara Parrino et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The antibiotic pipeline: reviving research and development and speeding drugs to market

(2017) Katherine H. Luepke et al.   Expert Review of Anti-Infective Therapy

Solvent-free synthesis of bacillamide analogues as novel cytotoxic and anti-inflammatory agents

(2016) Sunil Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Facile synthesis, structural evaluation, antimicrobial activity and synergistic effects of novel imidazo[1,2- a ]pyridine based organoselenium compounds

(2016) Sanjeev Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Therapeutic potential of coumarins as antiviral agents

(2016) Mohd. Zaheen Hassan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of some novel oxazolidinone-thiazole hybrids as potential antimicrobial, antioxidant and UV mediated DNA damage protecting agents

(2016) Kamalneet Kaur et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis and biological evaluation of some functionalized 1H-1,2,3-triazole tethered pyrazolo[3,4-b]pyridin-6(7H)-ones as antimicrobial and apoptosis inducing agents

(2016) Jayant Sindhu et al.   MEDICINAL CHEMISTRY RESEARCH

Novel Halogenated Pyrazine-Based Chalcones as Potential Antimicrobial Drugs

(2016) Marta Kucerova-Chlupacova et al.   MOLECULES

Antibacterial drug discovery in the resistance era

(2016) Eric D. Brown et al.   NATURE

Novel enaminone derived from thieno [2,3-b] thiene: Synthesis, x-ray crystal structure, HOMO, LUMO, NBO analyses and biological activity

(2015) Yahia Nasser Mabkhot et al.   Chemistry Central Journal

Multicomponent domino process for the synthesis of some novel 5-(arylidene)-3-((1-aryl-1H-1,2,3-triazol-4-yl)methyl)-thiazolidine-2,4-diones using PEG-400 as an efficient reaction medium and their antimicrobial evaluation

(2015) Jayant Sindhu et al.   CHINESE CHEMICAL LETTERS

Antimicrobial interactions: mechanisms and implications for drug discovery and resistance evolution

(2015) Tobias Bollenbach   CURRENT OPINION IN MICROBIOLOGY

Novel pyrazole-5-carboxamide and pyrazole–pyrimidine derivatives: Synthesis and anticancer activity

(2015) Jing Bo Shi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel (E)-1-aryl-2-(3,5-dimethyl-4-(aryldiazenyl)-1H-pyrazol-1-yl)ethanones: solvent-free synthesis and antimicrobial, antioxidant and UV-mediated DNA damage protective activity studies

(2015) Kamalneet Kaur et al.   MEDICINAL CHEMISTRY RESEARCH

Solvent-free synthesis of novel (E)-2-(3,5-dimethyl-4-(aryldiazenyl)-1H-pyrazol-1-yl)-4-arylthiazoles: determination of their biological activity

(2015) Kamalneet Kaur et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis of some pyrazolylaldehyde N-isonicotinoyl hydrazones and 2,5-disubstituted 1,3,4-oxadiazoles as DNA photocleaving agents

(2015) M. Kumar et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis of Some 2-(3-Alkyl/aryl-5-trifluoromethylpyrazol-1-yl)-4-(coumarin-3-yl)thiazoles as Novel Antibacterial Agents

(2015) Sunil Kumar et al.   SYNTHETIC COMMUNICATIONS

Synthesis, structure–activity relationships, and in vitro antibacterial and antifungal activity evaluations of novel pyrazole carboxylic and dicarboxylic acid derivatives

(2014) Samet Mert et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-arylethanones: Antibacterial, DNA photocleavage, and anticancer activities

(2014) Vinod Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, regioselective synthesis and cytotoxic evaluation of 2-aminoimidazole–quinoline hybrids against cancer and primary endothelial cells

(2014) Kuldeep Singh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Clonal Expansion during Staphylococcus aureus Infection Dynamics Reveals the Effect of Antibiotic Intervention

(2014) Gareth McVicker et al.   PLoS Pathogens

Mechanism of action of novel synthetic dodecapeptides against Candida albicans

(2013) Indresh Kumar Maurya et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Synthesis and pharmacological evaluation of some novel 2-(5-hydroxy-5-trifluoromethyl-4,5-dihydropyrazol-1-yl)-4-(coumarin-3-yl)thiazoles

(2013) Ranjana Aggarwal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of some new pyrazole-based 1,3-thiazoles and 1,3,4-thiadiazoles as anticancer agents

(2013) Kamal M. Dawood et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Pyrazole containing natural products: Synthetic preview and biological significance

(2013) Vinod Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New pyrazole derivatives containing 1,2,4-triazoles and benzoxazoles as potent antimicrobial and analgesic agents

(2013) A.M. Vijesh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Adverse Effects of Antimicrobials via Predictable or Idiosyncratic Inhibition of Host Mitochondrial Components

(2012) Alison E. Barnhill et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synthesis of some new 3,5-diamino-4-(4′-fluorophenylazo)-1-aryl/heteroarylpyrazoles as antimicrobial agents

(2012) Ranjana Aggarwal et al.   MEDICINAL CHEMISTRY RESEARCH

Rationale-Based,De NovoDesign of Dehydrophenylalanine-Containing Antibiotic Peptides and Systematic Modification in Sequence for Enhanced Potency

(2011) Sarika Pathak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synthesis and antimicrobial activity of amido linked pyrrolyl and pyrazolyl-oxazoles, thiazoles and imidazoles

(2011) V. Padmavathi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antibacterial activity of some 5-hydroxy-5-trifluoromethyl-4,5-dihydropyrazol-1-thiocarboxamides, 3-trifluoromethylpyrazol-1-thiocarboxamides and 4-aryl-2-(5(3)-trifluoromethyl-1-pyrazolyl)thiazoles

(2011) Ranjana Aggarwal et al.   JOURNAL OF FLUORINE CHEMISTRY

Synergy with Rifampin and Kanamycin Enhances Potency, Kill Kinetics, and Selectivity of De Novo-Designed Antimicrobial Peptides

(2010) A. Anantharaman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synthesis and evaluation of novel chloropyrrole molecules designed by molecular hybridization of common pharmacophores as potential antimicrobial agents

(2010) Rajesh A. Rane et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

An insight into the antifungal pipeline: selected new molecules and beyond

(2010) Luis Ostrosky-Zeichner et al.   NATURE REVIEWS DRUG DISCOVERY

Synthesis of coumarin heterocyclic derivatives with antioxidant activity and in vitro cytotoxic activity against tumour cells

(2009) Parameswaran Manojkumar et al.   ACTA PHARMACEUTICA

Antioxidant and antibacterial studies of arylazopyrazoles and arylhydrazonopyrazolones containing coumarin moiety

(2009) P. Manojkumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antiviral activity of new pyrazole and thiazole derivatives

(2009) Osama I. El-Sabbagh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antibacterial activity of some new thiazole and thiophene derivatives

(2009) A.M. Khalil et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of 4-benzyl-1,3-thiazole derivatives as potential anti-inflammatory agents: An analogue-based drug design approach

(2009) Ritesh N. Sharma et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

A Total Synthesis of (+)-Bacillamide B

(2009) Christopher Bray et al.   SYNLETT

Synthesis and pharmacological evaluation of a novel series of 5-(substituted)aryl-3-(3-coumarinyl)-1-phenyl-2-pyrazolines as novel anti-inflammatory and analgesic agents

(2008) Suresh Khode et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Management of candidiasis in the intensive care unit

(2007) S. Schelenz   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY