The antibiotic pipeline: reviving research and development and speeding drugs to market

Progress in the Fight Against Multidrug-Resistant Bacteria? A Review of U.S. Food and Drug Administration–Approved Antibiotics, 2010–2015

(2016) Dalia Deak et al.   ANNALS OF INTERNAL MEDICINE

Improving Conduct and Feasibility of Clinical Trials to Evaluate Antibacterial Drugs to Treat Hospital-Acquired Bacterial Pneumonia and Ventilator-Associated Bacterial Pneumonia: Recommendations of the Clinical Trials Transformation Initiative Antibacterial Drug Development Project Team

(2016) Charles Knirsch et al.   CLINICAL INFECTIOUS DISEASES

How Public–Private Collaborations Are Driving Solutions to the Antibacterial Drug Development Crisis

(2016) Leanne Madre et al.   CLINICAL INFECTIOUS DISEASES

Efficient Delivery of Investigational Antibacterial Agents via Sustainable Clinical Trial Networks

(2016) Anthony McDonnell et al.   CLINICAL INFECTIOUS DISEASES

Alternatives to antibiotics—a pipeline portfolio review

(2016) Lloyd Czaplewski et al.   LANCET INFECTIOUS DISEASES

Past, Present, and Future of Antibacterial Economics: Increasing Bacterial Resistance, Limited Antibiotic Pipeline, and Societal Implications

(2016) Katherine H. Luepke et al.   PHARMACOTHERAPY

Use of old antibiotics now and in the future from a pharmacokinetic/pharmacodynamic perspective

(2015) A.E. Muller et al.   CLINICAL MICROBIOLOGY AND INFECTION

Epidemiology of Carbapenem-Resistant Enterobacteriaceae in 7 US Communities, 2012-2013

(2015) Alice Y. Guh et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Time for a change: addressing R&D and commercialization challenges for antibacterials

(2015) D. J. Payne et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Global trends in antimicrobial use in food animals

(2015) Thomas P. Van Boeckel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rising Rates of Carbapenem-Resistant Enterobacteriaceae in Community Hospitals: A Mixed-Methods Review of Epidemiology and Microbiology Practices in a Network of Community Hospitals in the Southeastern United States

(2014) Joshua T. Thaden et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data

(2014) Thomas P Van Boeckel et al.   LANCET INFECTIOUS DISEASES

The FDA Reboot of Antibiotic Development

(2013) David M. Shlaes et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A comprehensive regulatory framework to address the unmet need for new antibacterial treatments

(2013) John H Rex et al.   LANCET INFECTIOUS DISEASES

The Safety Risks of Innovation

(2012) Thomas J. Moore et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Fix the antibiotics pipeline

(2011) Matthew A. Cooper et al.   NATURE

Challenges in the Design and Conduct of Clinical Trials for Hospital‐Acquired Pneumonia and Ventilator‐Associated Pneumonia: An Industry Perspective

(2010) Steven L. Barriere   CLINICAL INFECTIOUS DISEASES

Considerations in Undertaking a Clinical Development Program for Hospital‐Acquired Bacterial Pneumonia and/or Ventilator‐Associated Bacterial Pneumonia

(2010) George H. Talbot   CLINICAL INFECTIOUS DISEASES