Effects of genetic variants in the TSPO gene on protein structure and stability

TSPO PET for glioma imaging using the novel ligand 18F-GE-180: first results in patients with glioblastoma

(2017) Nathalie L. Albert et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

A role for TSPO in mitochondrial Ca2+ homeostasis and redox stress signaling

(2017) Jemma Gatliff et al.   Cell Death & Disease

Cholesterol-mediated allosteric regulation of the mitochondrial translocator protein structure

(2017) Garima Jaipuria et al.   Nature Communications

TSPO imaging using the novel PET ligand [18F]GE-180: quantification approaches in patients with multiple sclerosis

(2017) Lena Vomacka et al.   EJNMMI Research

The translocator protein gene is associated with symptom severity and cerebral pain processing in fibromyalgia

(2016) Eva Kosek et al.   BRAIN BEHAVIOR AND IMMUNITY

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

(2016) Haim Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

The methodology of TSPO imaging with positron emission tomography

(2015) Federico E. Turkheimer et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Identification of a Key Cholesterol Binding Enhancement Motif in Translocator Protein 18 kDa

(2015) Fei Li et al.   BIOCHEMISTRY

PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels

(2015) Yongwook Choi et al.   BIOINFORMATICS

Backbone and side-chain resonance assignment of the A147T polymorph of mouse TSPO in complex with a high-affinity radioligand

(2015) Mariusz Jaremko et al.   Biomolecular NMR Assignments

Better prediction of functional effects for sequence variants

(2015) Maximilian Hecht et al.   BMC GENOMICS

Structural Integrity of the A147T Polymorph of Mammalian TSPO

(2015) Mariusz Jaremko et al.   CHEMBIOCHEM

Synonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-β signaling

(2015) Ulrike Friedrich et al.   HUMAN MOLECULAR GENETICS

The Translocator Protein 18 kDa (TSPO) and Its Role in Mitochondrial Biology and Psychiatric Disorders

(2015) Vladimir Milenkovic et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Structure and activity of tryptophan-rich TSPO proteins

(2015) Y. Guo et al.   SCIENCE

Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism

(2015) F. Li et al.   SCIENCE

Role of Translocator Protein Density, a Marker of Neuroinflammation, in the Brain During Major Depressive Episodes

(2015) Elaine Setiawan et al.   JAMA Psychiatry

Peripheral Benzodiazepine Receptor/Translocator Protein Global Knock-out Mice Are Viable with No Effects on Steroid Hormone Biosynthesis

(2014) Lan N. Tu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Mitochondrial Translocator Protein in Complex with a Diagnostic Ligand

(2014)  ukasz Jaremko et al.   SCIENCE

Positron emission tomography and functional characterization of a complete PBR/TSPO knockout

(2014) Richard B. Banati et al.   Nature Communications

Protter: interactive protein feature visualization and integration with experimental proteomic data

(2013) Ulrich Omasits et al.   BIOINFORMATICS

The Role of PBR/TSPO in Steroid Biosynthesis Challenged

(2013) Douglas M. Stocco   ENDOCRINOLOGY

Translocator Protein/Peripheral Benzodiazepine Receptor Is Not Required for Steroid Hormone Biosynthesis

(2013) Kanako Morohaku et al.   ENDOCRINOLOGY

Proteome-Wide Measurement of Protein Half-Lives and Translation Rates in Vasopressin-Sensitive Collecting Duct Cells

(2013) P. C. Sandoval et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Bipolar Disorder is associated with the rs6971 polymorphism in the gene encoding 18kDa Translocator Protein (TSPO)

(2013) Alessandro Colasanti et al.   PSYCHONEUROENDOCRINOLOGY

Predicting the Functional, Molecular, and Phenotypic Consequences of Amino Acid Substitutions using Hidden Markov Models

(2012) Hashem A. Shihab et al.   HUMAN MUTATION

An 18-kDa Translocator Protein (TSPO) Polymorphism Explains Differences in Binding Affinity of the PET Radioligand PBR28

(2011) David R Owen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Understanding the contribution of synonymous mutations to human disease

(2011) Zuben E. Sauna et al.   NATURE REVIEWS GENETICS

Genome structural variation discovery and genotyping

(2011) Can Alkan et al.   NATURE REVIEWS GENETICS

Mixed-Affinity Binding in Humans with 18-kDa Translocator Protein Ligands

(2010) D. R. J. Owen et al.   JOURNAL OF NUCLEAR MEDICINE

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

(2010) Rainer Rupprecht et al.   NATURE REVIEWS DRUG DISCOVERY

The Spontaneous Ala147Thr Amino Acid Substitution within the Translocator Protein Influences Pregnenolone Production in Lymphomonocytes of Healthy Individuals

(2009) Barbara Costa et al.   ENDOCRINOLOGY

Functional annotations improve the predictive score of human disease-related mutations in proteins

(2009) Remo Calabrese et al.   HUMAN MUTATION

Pathogenic or not? And if so, then how? Studying the effects of missense mutations using bioinformatics methods

(2009) Janita Thusberg et al.   HUMAN MUTATION

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Ala147Thr substitution in translocator protein is associated with adult separation anxiety in patients with depression

(2009) Barbara Costa et al.   PSYCHIATRIC GENETICS

A three-state prediction of single point mutations on protein stability changes

(2008) Emidio Capriotti et al.   BMC BIOINFORMATICS