A role for TSPO in mitochondrial Ca2+ homeostasis and redox stress signaling

Control of Mitochondrial Remodeling by the ATPase Inhibitory Factor 1 Unveils a Pro-survival Relay via OPA1

(2017) Danilo Faccenda et al.   Cell Reports

TSPO: kaleidoscopic 18-kDa amid biochemical pharmacology, control and targeting of mitochondria

(2016) J. Gatliff et al.   BIOCHEMICAL JOURNAL

Mitonuclear communication in homeostasis and stress

(2016) Pedro M. Quirós et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TSPO Finds NOX2 in Microglia for Redox Homeostasis

(2016) Tomás R. Guilarte et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Inhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis

(2016) S Neitemeier et al.   Cell Death & Disease

TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control

(2014) Jemma Gatliff et al.   Autophagy

Peripheral Benzodiazepine Receptor/Translocator Protein Global Knock-out Mice Are Viable with No Effects on Steroid Hormone Biosynthesis

(2014) Lan N. Tu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type 2 Transglutaminase, mitochondria and Huntington's disease: Menage a trois

(2014) Sara Altuntas et al.   MITOCHONDRION

Calcium signaling and mitochondrial destabilization in the triggering of the NLRP3 inflammasome

(2014) Tiffany Horng   TRENDS IN IMMUNOLOGY

Positron emission tomography and functional characterization of a complete PBR/TSPO knockout

(2014) Richard B. Banati et al.   Nature Communications

Ca2+in quality control

(2013) Daniel A East et al.   Autophagy

Translocator Protein/Peripheral Benzodiazepine Receptor Is Not Required for Steroid Hormone Biosynthesis

(2013) Kanako Morohaku et al.   ENDOCRINOLOGY

Mitochondrial Small Conductance SK2 Channels Prevent Glutamate-induced Oxytosis and Mitochondrial Dysfunction

(2013) Amalia M. Dolga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The inner and outer compartments of mitochondria are sites of distinct cAMP/PKA signaling dynamics

(2013) Konstantinos Lefkimmiatis et al.   JOURNAL OF CELL BIOLOGY

Dexras1, a Small GTPase, Is Required for Glutamate-NMDA Neurotoxicity

(2013) Y. Chen et al.   JOURNAL OF NEUROSCIENCE

Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling

(2013) Clare V Logan et al.   NATURE GENETICS

Golgi Protein ACBD3 Mediates Neurotoxicity Associated with Huntington’s Disease

(2013) Juan I. Sbodio et al.   Cell Reports

Activation of CaMKII as a key regulator of reactive oxygen species production in diabetic rat heart

(2012) Satoru Nishio et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Evaluation of age-related changes in translocator protein (TSPO) in human brain using 11C-[R]-PK11195 PET

(2012) Ajay Kumar et al.   Journal of Neuroinflammation

Reactive Astrocytes Overexpress TSPO and Are Detected by TSPO Positron Emission Tomography Imaging

(2012) S. Lavisse et al.   JOURNAL OF NEUROSCIENCE

A practical guide to evaluating colocalization in biological microscopy

(2011) Kenneth W. Dunn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A Sensitive and Quantitative Technique for Detecting Autophagic Events Based on Lysosomal Delivery

(2011) Hiroyuki Katayama et al.   CHEMISTRY & BIOLOGY

After half a century mitochondrial calcium in- and efflux machineries reveal themselves

(2011) Ilaria Drago et al.   EMBO JOURNAL

Mitochondrial Ca2+ and ROS take center stage to orchestrate TNF-α–mediated inflammatory responses

(2011) Laura A. Dada et al.   JOURNAL OF CLINICAL INVESTIGATION

Calcium transport across the inner mitochondrial membrane: Molecular mechanisms and pharmacology

(2011) György Csordás et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Calcium/Calmodulin-Dependent Kinase II Mediates the Phosphorylation and Activation of NADPH Oxidase 5

(2011) D. Pandey et al.   MOLECULAR PHARMACOLOGY

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

(2011) Diego De Stefani et al.   NATURE

Phosphorylation of Voltage-Dependent Anion Channel by Serine/Threonine Kinases Governs Its Interaction with Tubulin

(2011) Kely L. Sheldon et al.   PLoS One

Protein Kinase Cε Regulation of Translocator Protein (18 kDa)TspoGene Expression Is Mediated through a MAPK Pathway Targeting STAT3 and c-Jun Transcription Factors

(2010) Amani Batarseh et al.   BIOCHEMISTRY

Excitotoxicity effects of glutamate on human neuroblastoma SH-SY5Y cells via oxidative damage

(2010) Zhong-Wei Sun et al.   Neuroscience Bulletin

Nox proteins in signal transduction

(2009) David I. Brown et al.   FREE RADICAL BIOLOGY AND MEDICINE

Translocator protein (TSPO 18kDa) is expressed by neural stem and neuronal precursor cells

(2009) Balázs Varga et al.   NEUROSCIENCE LETTERS

Modulation of intracellular Ca2+ signalling in HeLa cells by the apoptotic cell death enhancer PK11195

(2008) Michelangelo Campanella et al.   BIOCHEMICAL PHARMACOLOGY

Regulation of Mitochondrial Structure and Function by the F1Fo-ATPase Inhibitor Protein, IF1

(2008) Michelangelo Campanella et al.   Cell Metabolism

Classical Inhibitors of NOX NAD(P)H Oxidases Are Not Specific

(2008) Elisabetta Aldieri et al.   CURRENT DRUG METABOLISM

CaM kinase Iα–induced phosphorylation of Drp1 regulates mitochondrial morphology

(2008) Xiao-Jian Han et al.   JOURNAL OF CELL BIOLOGY

Translocator protein 18 kDa (TSPO): Molecular sensor of brain injury and repair

(2008) Ming-Kai Chen et al.   PHARMACOLOGY & THERAPEUTICS

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

(2008) G. M. Cereghetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacological PKA Inhibition: All May Not Be What It Seems

(2008) A. J. Murray   Science Signaling