Article
Chemistry, Medicinal
Yan-Fei Sui, Mohammad Fawad Ansari, Bo Fang, Shao-Lin Zhang, Cheng-He Zhou
Summary: Novel purinylthiazolylethanone derivative 8c shows significant inhibitory action against C. albicans, with no detectable resistance and low toxicity. The compound kills fungi by damaging cell wall and membrane disruption, hinder the growth of fungal biofilm. Imbalance of redox equilibrium leads to oxidative damage to fungal cells and fungicidal effect.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Review
Biochemistry & Molecular Biology
Mingyue Gou, Peter Balint-Kurti, Mingliang Xu, Qin Yang
Summary: In contrast to large-effect qualitative disease resistance, quantitative disease resistance (QDR) exhibits partial and generally durable resistance and has been extensively utilized in crop breeding. The molecular mechanisms underlying QDR remain largely unknown but considerable progress has been made in recent years, revealing the involvement of various genes with diverse biological functions. Understanding the diverse mechanisms and effective deployment of QDR will enable the production of more durably resistant, resilient crops.
JOURNAL OF INTEGRATIVE PLANT BIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Dan Wang, Xuebin Wan, Xiaoli Du, Zhuxia Zhong, Jian Peng, Qi Xiong, Jin Chai, Siwen Jiang
Summary: The study reveals that leucine can increase the expressions of SLC38A9 and SLC36A1, leading to mTORC1 activation, and SLC38A9 interacts with SLC36A1 to enhance each other's expression levels and locations on the lysosomal surface. Interacting proteins of SLC38A9 in C2C12 cells are involved in amino acid sensing mechanism, mTORC1 signaling pathway, and protein synthesis, providing a resource for future investigations of skeletal muscle mass.
Article
Plant Sciences
Moumita Srivastava, Ari Sadanandom, Anjil Kumar Srivastava
Summary: The translation discusses the critical role of post-translational modifications (PTMs) in regulating plant growth and development, and the challenges in understanding the functional implications of PTMs on plant cellular signaling.
PHYSIOLOGIA PLANTARUM
(2021)
Article
Biochemistry & Molecular Biology
Anna S. Barashkova, Dmitry Y. Ryazantsev, Eugene A. Rogozhin
Summary: This study investigates the structural determinants of antimicrobial activity in plant alpha-hairpinins peptides. The researchers found that spatial structure, surface charge, and hydrophobicity level all contribute to the antimicrobial properties of these peptides. Through the synthesis and testing of different forms of alpha-hairpinins peptides, they demonstrate that alterations in the peptide structure and amino acid substitutions result in weakened antimicrobial activity. Additionally, this study provides the first description of the antibacterial activity of cereal alpha-hairpinins against Gram-positive bacteria.
Article
Biochemistry & Molecular Biology
Ya Chun Yu, Jung Min Han, Sunghoon Kim
Summary: Aminoacyl-tRNA synthetases play essential roles in protein synthesis and recent studies have revealed their previously unknown biological functions beyond catalytic roles. Sensing intracellular nutrients is crucial for cell physiology, and certain types of ARSs may be involved in sensing and signaling their cognate amino acids within cells.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
(2021)
Article
Plant Sciences
Bing Duan, Huaying Du, Wei Zhang, Jing Wang, Zhipeng Cai, Yonggen Shen, Tenghuan Huang, Jie Yuan, Zengyu Gan, Jinyin Chen, Liqin Zhu
Summary: This study found that hydrogen sulfide can enhance the resistance of kiwifruit to soft rot and inhibit the growth of the pathogen. It also identified the metabolic changes in the plant induced by hydrogen sulfide. These findings have significant implications for improving the postharvest storage quality of kiwifruit.
FRONTIERS IN PLANT SCIENCE
(2022)
Review
Chemistry, Inorganic & Nuclear
Nobuto Yoshinari, Naoto Kuwamura, Tatsuhiro Kojima, Takumi Konno
Summary: Thiol-containing amino acids have been extensively studied as chelating ligands, forming coordination compounds with various metal elements and exhibiting a capacity to form multinuclear structures. Recent research has demonstrated that the use of metal complexes with thiol-containing amino acids allows for the selective introduction of secondary metal ions, enabling the rational design of multinuclear and metallosupramolecular coordination compounds.
COORDINATION CHEMISTRY REVIEWS
(2023)
Article
Plant Sciences
Eva Dvorak Tomastikova, Fen Yang, Kristina Mlynarova, Said Hafidh, Sarka Schorova, Alzbeta Kusova, Marketa Pernisova, Tereza Prerovska, Bozena Klodova, David Honys, Jiri Fajkus, Ales Pecinka, Petra Prochazkova Schrumpfova
Summary: RUVBL1 and RUVBL2 are crucial for the proper development of male and female gametophytes in Arabidopsis. Mutations in these genes result in abnormal embryo sac structure and nuclear numbers. The expression of these proteins is observed in pollen grains, embryo sac, and tapetum cells, playing important roles in reproductive development.
Article
Plant Sciences
Qi Li, Zhaoqi Hou, Dongqin Zhou, Mingyun Jia, Shipeng Lu, Jinping Yu
Summary: The bacterial strain JR48 is found to promote plant growth and induce resistance to black rot in cruciferous plants. JR48 enhances the accumulation and response of salicylic acid to stimulate plant defense responses.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Engineering, Environmental
Yangyang Chu, Xinyu Zhang, Xuefeng Yu, Chuanhao Yan, Yu Yang, Guofeng Shen, Xuejun Wang, Shu Tao, Xilong Wang
Summary: The novel magnetic nanosphere TSF showed high efficiency in removing antimony, but the presence of cysteine in the liquid phase led to a reduction in antimony removal efficiency by competing with TSF. The interaction between antimony and cysteine changed with pH, impacting the speciation of antimony and ultimately decreasing antimony removal efficiency by TSF.
CHEMICAL ENGINEERING JOURNAL
(2021)
Review
Plant Sciences
Muhammad Rehman, Muhammad Sulaman Saeed, Xingming Fan, Abdul Salam, Raheel Munir, Muhammad Umair Yasin, Ali Raza Khan, Sajid Muhammad, Bahar Ali, Imran Ali, Jamshaid Khan, Yinbo Gan
Summary: Plants have developed complex mechanisms to cope with stressors, and phytohormones like jasmonic acid play a crucial role in regulating physiological and molecular processes to protect plants from biotic and abiotic stress. Jasmonic acid is involved in plant defense against biotic stress and alleviating various abiotic stressors, and its intricate biosynthetic pathways and mechanisms are still not well understood.
Review
Biochemistry & Molecular Biology
Dmitry Lapin, Oliver Johanndrees, Zhongshou Wu, Xin Li, Jane E. Parker
Summary: Protein domains play a crucial role in immune signaling in both prokaryotes and eukaryotes. TIR-based signaling in plants is essential for host defenses and balanced for healthy tissues. Specialized protein modules have evolved in seed plants to connect TIR domain signaling with effective defense responses.
Article
Nutrition & Dietetics
Zhen Dong, John P. Richie, Xiang Gao, Laila Al-Shaar, Sailendra N. Nichenametla, Biyi Shen, David Orentreich
Summary: Excess intake of sulfur amino acids is associated with a higher risk of type 2 diabetes. Dietary patterns low in sulfur amino acids could help prevent type 2 diabetes.
JOURNAL OF NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Payal Srivastava, Anchal Garg, Rajesh Chandra Misra, Chandan Singh Chanotiya, Sumit Ghosh
Summary: This study analyzed the glycosyltransferase activity and levels of labdane diterpenes in plant specialized metabolism, identifying a novel UGT86 member ApUGT12 that catalyzes C19-O-glucosylation of diterpenes with strict scaffold selectivity. The findings suggest the involvement of ApUGT12 in scaffold-selective C19-O-glucosylation of labdane diterpenes in plants, which could be valuable for developing plant chemotypes and synthesizing pharmacologically relevant diterpenes.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2021)
Article
Biochemical Research Methods
Franck Merlier, Nabila Imatoukene, Stephane Octave, Jean-Marc Nicaud, Brigitte Thomasset
JOURNAL OF CHROMATOGRAPHY A
(2018)
Article
Microbiology
Marie-Helene Corre, Vincent Delafont, Anasthasia Legrand, Jean-Marc Berjeaud, Julien Verdon
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Agronomy
Gabriel Roblin, Estelle Luini, Pierrette Fleurat-Lessard, Philippe Larignon, Jean-Marc Berjeaud
Article
Multidisciplinary Sciences
Alexandre Crepin, Jean-Francois Jegou, Sonia Andre, Florine Ecale, Anastasia Croitoru, Anne Cantereau, Jean-Marc Berjeaud, Ali Ladram, Julien Verdon
SCIENTIFIC REPORTS
(2020)
Article
Genetics & Heredity
Thomas Becking, Carine Delaunay, Richard Cordaux, Jean-Marc Berjeaud, Christine Braquart-Varnier, Julien Verdon
Article
Plant Sciences
Philippe Michonneau, Pierrette Fleurat-Lessard, Anne Cantereau, Alexandre Crepin, Gabriel Roblin, Jean-Marc Berjeaud
Summary: Actin microfilaments are involved in the regulation of nutrient uptake in root and leaf cells, showing different characteristics in their expression. The co-localization of actin and sucrose transporters in the plasma membrane suggests a potential functional role in sucrose uptake. Pharmacological inhibitors like cytochalasin B and D inhibit sucrose and valine uptake in a concentration-dependent manner.
PHYSIOLOGIA PLANTARUM
(2021)
Article
Microbiology
Florine Ecale, Abdelaziz El Houari, Stephanie Crapart, Jerome Laparre, Manilduth Ramnath, Jean-Marc Berjeaud, Marie-Helene Rodier, Alexandre Crepin
Summary: The study focuses on the sensitivity of 30 bacterial strains representing the intestinal microbiota core to 8 antibiotics, and investigates the chemical modification of antibiotics by bacteria. It finds that some antibiotics have little impact on core microbiota strain growth, while others inhibit the growth of numerous strains. The research demonstrates that the bacteria composing the intestinal core microbiome can modify certain antibiotics, highlighting the reciprocal relationship between antibiotics and the intestinal microbiota core.
Article
Evolutionary Biology
Benjamin Herran, Pierre Greve, Jean-Marc Berjeaud, Joanne Bertaux, Alexandre Crepin
Summary: Legionella spp. contain a quorum sensing system named Legionella quorum sensing that regulates virulence, but no correlation was found between pathogenicity and the presence of this system.
GENOME BIOLOGY AND EVOLUTION
(2021)
Article
Microbiology
Marie-Helene Corre, Anne Mercier, Mathilde Bouteiller, Alix Khalil, Christophe Ginevra, Segolene Depayras, Charly Dupont, Meg Rouxel, Mathias Gallique, Laettitia Grac, Sophie Jarraud, David Giron, Annabelle Merieau, Jean-Marc Berjeaud, Julien Verdon
Summary: Studies have shown that volatile substances emitted by Pseudomonas fluorescens strain MFE01 can inhibit the growth of Legionella pneumophila at a distance. This discovery highlights the potential of bacterial volatiles as potent anti-Legionella agents and suggests novel strategies for combating Legionella infections.
MICROBIOLOGY SPECTRUM
(2021)
Article
Microbiology
Aurelien Alafaci, Alexandre Crepin, Sabine Beaubert, Jean-Marc Berjeaud, Vincent Delafont, Julien Verdon
Summary: Ixodes ricinus, the most common hard tick species in Europe, was studied in France to assess bacterial diversity using high-throughput sequencing. The study identified over 700 bacterial genera, with 20 abundantly represented, and found a core internal microbiota in the nymphs. Additionally, 20 individuals carrying Borreliella, with B. afzelii being the most abundant species, were detected, raising questions about interactions between these bacteria and the internal microbiota communities.
Article
Microbiology
Pierrette Fleurat-Lessard, Estelle Luini, Sylvain La Camera, Florence Thibault, Gabriel Roblin, Jean-Marc Berjeaud
Summary: In esca disease affecting grapevines, the fungi Phaeomoniella chlamydospora and Phaeoacremonium minimum obtain nutrition from xylem sap and enzymatic breakdown residues. The secretion of lignin peroxidase, manganese peroxidase, and laccase by these fungi was quantified in infected woody tissues, and it was found that Phaeoacremonium minimum had higher enzyme detection. The supply of different carbohydrates had differential effects on fungal growth and polypeptide secretion, suggesting a potential influence on the aggressiveness of these pathogens.
ARCHIVES OF MICROBIOLOGY
(2023)
Review
Microbiology
Mickael Guerin, Marc Shawky, Ahed Zedan, Stephane Octave, Berangere Avalle, Irene Maffucci, Severine Padiolleau-Lefevre
Summary: With a high number of cases each year, Lyme borreliosis (LB) is the most common tick-borne illness in the world. The diagnosis of LB is controversial and relies on an indirect approach with low sensitivity. Early and proper detection is crucial for effective treatment and preventing the persistence of the pathogen. This review focuses on improving the current diagnosis and innovative methods for more accurate detection of LB.
Article
Food Science & Technology
Meg Rouxel, Manon Barthe, Pierre Marchand, Camille Juin, Leslie Mondamert, Thierry Berges, Philippe Blanc, Julien Verdon, Jean-Marc Berjeaud, Willy Aucher
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2020)
Article
Microbiology
Sophie Rodrigues, Christine Paillard, Sabine Van Dillen, Ali Tahrioui, Jean-Marc Berjeaud, Alain Dufour, Alexis Bazire
Article
Plant Sciences
Wanli You, Jinglin Zhang, Xueyin Ru, Feng Xu, Zhengguo Wu, Peng Jin, Yonghua Zheng, Shifeng Cao
Summary: This study investigated the effect of calcium chloride (CaCl2) treatment on GABA accumulation in fresh-cut cantaloupe and the underlying mechanisms. The results showed that CaCl2 treatment increased GABA content and the activities of GAD and SSADH enzymes, while reducing glutamate content and GABA-T activity. Additionally, CaCl2 treatment upregulated the expressions of CmCML11 and CmCAMTA5, as well as several GABA shunt genes, through the transcriptional activation by CmCAMTA5. Furthermore, the interaction between CmCML11 and CmCAMTA5 enhanced the transcriptional activation of GABA shunt genes. Overall, this study reveals that CaCl2 treatment promotes GABA accumulation in fresh-cut cantaloupe through the combined effect of CmCML11 and CmCAMTA5 in regulating the expressions of GABA shunt genes.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Min Wang, Yupeng Wang, Xiaohui Wang, Guangwei Wei, Huiyi Yang, Xi Yang, Tinghai Shen, Huijie Qu, Sheng Fang, Ziming Wu
Summary: This study identified the high nitrogen use efficiency (NUE) black sesame variety 17-156 and analyzed its underlying physiological and molecular mechanisms. The results showed that 17-156 possesses a sophisticated nitrogen metabolizing machinery to uptake and assimilate higher quantities of inorganic nitrogen, simultaneously improving carbon metabolism and growth. Many important genes were up-regulated in 17-156 under high nitrogen condition. Additionally, 38 potential candidate genes were identified for future studies to improve sesame's NUE. These findings provide valuable resources for understanding the regulatory network of nitrogen metabolism and developing sesame cultivars with improved NUE.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
He Dong, Chongmei Xu, Chengtao Zhang, Li Zhang, Yaqin Yao, Suiqi Zhang
Summary: The study found that short cells in maize leaves not only improve leaf mechanical support and photosynthetic performance, enhance drought resistance, but also participate in stomatal regulation.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Na Liu, Wenyan Shang, Mengxin Guan, Jibin Xiao, Guangxiang Tian, Baozhan Ma, Wenjing Shang, Xu Li, Shijia Zhao, Chuang Li, Kun Cheng, Wenming Zheng
Summary: This study cloned the full-length cDNA sequence of TaSPX3 gene in wheat and found that TaSPX3 responds to low phosphorus stress in multiple wheat genotypes. Overexpressing TaSPX3 can alleviate phosphorus deficiency symptoms and promote plant growth in Arabidopsis. The study also revealed the interaction of TaSPX3 with other genes related to the phosphorus starvation signaling pathway.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Kongyuan Wu, Lizhen Wang, Zihan Wu, Ziqing Liu, Zengfei Li, Jun Shen, Shengjie Shi, Hong Liu, Christopher Rensing, Renwei Feng
Summary: Selenium (Se) can reduce uptake and translocation of cadmium (Cd) in plants by regulating root morphology. This study investigated the effects of Se(IV) on root exudates, root morphology, root endogenous hormones, and Cd uptake efficiency in rice under Cd stress. The results showed that Se(IV) significantly reduced Cd concentrations in shoots and roots, and decreased Cd uptake efficiency via root hairs. Se(IV) also affected root morphology, root exudates, and the synthesis of hormones like IAA and JA. However, transcriptome analysis revealed no upregulated differentially expressed genes (DEGs) in IAA synthesis.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Di Wang, Huaifang Zhang, Xuefei Hu, Haizhen Zhang, Shuang Feng, Aimin Zhou
Summary: This study identified a cell number regulator gene called SlCNR8 in willow, which enhances resistance to trace metals in transgenic poplar seedlings. SlCNR8 reduces Cd uptake and accumulation, and can be used as a candidate gene for genetic improvement of phytostabilisation of trace metals.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)