Characterization of DCL4 missense alleles provides insights into its ability to process distinct classes of dsRNA substrates

RNase III nucleases from diverse kingdoms serve as antiviral effectors

(2017) Lauren C. Aguado et al.   NATURE

The C-terminal dsRNA-binding domain of Drosophila Dicer-2 is crucial for efficient and high-fidelity production of siRNA and loading of siRNA to Argonaute2

(2017) Suresh K. Kandasamy et al.   RNA

DNA Methylation Influences the Expression of DICER-LIKE4 Isoforms, Which Encode Proteins of Alternative Localization and Function

(2016) Nathan Pumplin et al.   PLANT CELL

A One Precursor One siRNA Model for Pol IV-Dependent siRNA Biogenesis

(2015) Jixian Zhai et al.   CELL

Drosophila Dicer-2 Cleavage Is Mediated by Helicase- and dsRNA Termini-Dependent States that Are Modulated by Loquacious-PD

(2015) Niladri K. Sinha et al.   MOLECULAR CELL

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Production of functional small interfering RNAs by an amino-terminal deletion mutant of human Dicer

(2015) Edward M. Kennedy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Pol IV and RDR2-dependent precursors of 24 nt siRNAs guiding de novo DNA methylation in Arabidopsis

(2015) Todd Blevins et al.   eLife

The Diversity, Biogenesis, and Activities of Endogenous Silencing Small RNAs inArabidopsis

(2014) Nicolas G. Bologna et al.   Annual Review of Plant Biology

A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer

(2014) Yuan Tian et al.   MOLECULAR CELL

miRNAs trigger widespread epigenetically activated siRNAs from transposons in Arabidopsis

(2014) Kate M. Creasey et al.   NATURE

tasiRNAdb: a database of ta-siRNA regulatory pathways

(2013) Changqing Zhang et al.   BIOINFORMATICS

Reconstructing de novo silencing of an active plant retrotransposon

(2013) Arturo Marí-Ordóñez et al.   NATURE GENETICS

Intersection of Small RNA Pathways in Arabidopsis thaliana Sub-Nuclear Domains

(2013) Olga Pontes et al.   PLoS One

Genome-wide identification of genes regulated intransby transposable element small interfering RNAs

(2013) Andrea D McCue et al.   RNA Biology

Cytoplasmic Arabidopsis AGO7 accumulates in membrane-associated siRNA bodies and is required for ta-siRNA biogenesis

(2012) Virginie Jouannet et al.   EMBO JOURNAL

Differential effects of viral silencing suppressors on siRNA and miRNA loading support the existence of two distinct cellular pools of ARGONAUTE1

(2012) Gregory Schott et al.   EMBO JOURNAL

Evolution of Animal and Plant Dicers: Early Parallel Duplications and Recurrent Adaptation of Antiviral RNA Binding in Plants

(2012) Krishanu Mukherjee et al.   MOLECULAR BIOLOGY AND EVOLUTION

Sequencing of RDR6-dependent double-stranded RNAs reveals novel features of plant siRNA biogenesis

(2012) Rajendran Rajeswaran et al.   NUCLEIC ACIDS RESEARCH

The Helicase and RNaseIIIa Domains of Arabidopsis Dicer-Like1 Modulate Catalytic Parameters during MicroRNA Biogenesis

(2012) C. Liu et al.   PLANT PHYSIOLOGY

Gene Expression and Stress Response Mediated by the Epigenetic Regulation of a Transposable Element Small RNA

(2012) Andrea D. McCue et al.   PLoS Genetics

Dicer's Helicase Domain Discriminates dsRNA Termini to Promote an Altered Reaction Mode

(2011) Noah C. Welker et al.   MOLECULAR CELL

Dicer recognizes the 5′ end of RNA for efficient and accurate processing

(2011) Jong-Eun Park et al.   NATURE

RDR6-mediated synthesis of complementary RNA is terminated by miRNA stably bound to template RNA

(2011) Rajendran Rajeswaran et al.   NUCLEIC ACIDS RESEARCH

Arabidopsis DRB4 protein in antiviral defense against Turnip yellow mosaic virus infection

(2011) Anna Jakubiec et al.   PLANT JOURNAL

Double-stranded RNA binding proteins DRB2 and DRB4 have an antagonistic impact on polymerase IV-dependent siRNA levels in Arabidopsis

(2011) T. Pelissier et al.   RNA

Specific requirement of DRB4, a dsRNA-binding protein, for the in vitro dsRNA-cleaving activity of Arabidopsis Dicer-like 4

(2011) A. Fukudome et al.   RNA

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Arabidopsis RNA-Dependent RNA Polymerases and Dicer-Like Proteins in Antiviral Defense and Small Interfering RNA Biogenesis during Turnip Mosaic Virus Infection

(2010) H. Garcia-Ruiz et al.   PLANT CELL

Structure of the Arabidopsis thaliana DCL4 DUF283 domain reveals a noncanonical double-stranded RNA-binding fold for protein-protein interaction

(2010) H. Qin et al.   RNA

Dicer's helicase domain is required for accumulation of some, but not all, C. elegans endogenous siRNAs

(2010) N. C. Welker et al.   RNA

SGS3 and RDR6 interact and colocalize in cytoplasmic SGS3/RDR6-bodies

(2009) Naoyoshi Kumakura et al.   FEBS LETTERS

Requirement for the ERI/DICER Complex in Endogenous RNA Interference and Sperm Development in Caenorhabditis elegans

(2009) Derek M. Pavelec et al.   GENETICS

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes

(2009) Yanli Wang et al.   NATURE

Rapid, combinatorial analysis of membrane compartments in intact plants with a multicolor marker set

(2009) Niko Geldner et al.   PLANT JOURNAL

Identification of MIR390a precursor processing-defective mutants in Arabidopsis by direct genome sequencing

(2009) J. T. Cuperus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A dominant mutation in DCL1 suppresses the hyl1 mutant phenotype by promoting the processing of miRNA

(2009) Y. Tagami et al.   RNA

The Arabidopsis thaliana double-stranded RNA binding protein DRB1 directs guide strand selection from microRNA duplexes

(2009) A. L. Eamens et al.   RNA

Specificity of ARGONAUTE7-miR390 Interaction and Dual Functionality in TAS3 Trans-Acting siRNA Formation

(2008) Taiowa A. Montgomery et al.   CELL

The roles of plant dsRNA-binding proteins in RNAi-like pathways

(2008) Shaun J. Curtin et al.   FEBS LETTERS

Autoinhibition of Human Dicer by Its Internal Helicase Domain

(2008) Enbo Ma et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural and Genetic Requirements for the Biogenesis of Tobacco Rattle Virus-Derived Small Interfering RNAs

(2008) L. Donaire et al.   JOURNAL OF VIROLOGY

AGO1-miR173 complex initiates phased siRNA formation in plants

(2008) T. A. Montgomery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA