Screening a repurposing library, the Medicines for Malaria Venture Stasis Box, against Schistosoma mansoni

Working towards New Drugs against Parasitic Worms in a Public-Development Partnership

(2018) Sarah Preston et al.   TRENDS IN PARASITOLOGY

Screening of the ‘Stasis Box’ identifies two kinase inhibitors under pharmaceutical development with activity against Haemonchus contortus

(2017) Yaqing Jiao et al.   Parasites & Vectors

Poster Sessions

(2017)   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Controlling schistosomiasis with praziquantel: How much longer without a viable alternative?

(2017) Robert Bergquist et al.   Infectious Diseases of Poverty

Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2016) Nicholas J Kassebaum et al.   LANCET

Structure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoni

(2016) Thavy Long et al.   PLoS Neglected Tropical Diseases

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

(2016) Wesley C. Van Voorhis et al.   PLoS Pathogens

Re-positioning protein-kinase inhibitors against schistosomiasis

(2015) Verena Gelmedin et al.   Future Medicinal Chemistry

Repurposing of anticancer drugs: in vitro and in vivo activities against Schistosoma mansoni

(2015) Noemi Cowan et al.   Parasites & Vectors

Activity Profile of an FDA-Approved Compound Library against Schistosoma mansoni

(2015) Gordana Panic et al.   PLoS Neglected Tropical Diseases

Human schistosomiasis

(2014) Daniel G Colley et al.   LANCET

Schistosomiasis control: praziquantel forever?

(2014) Donato Cioli et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Repurposing drugs for the treatment and control of helminth infections

(2014) Gordana Panic et al.   International Journal for Parasitology-Drugs and Drug Resistance

Compound library screening identified Akt/PKB kinase pathway inhibitors as potential key molecules for the development of new chemotherapeutics against schistosomiasis

(2014) Marion Morel et al.   International Journal for Parasitology-Drugs and Drug Resistance

Receptor tyrosine kinases and schistosome reproduction: new targets for chemotherapy

(2014) Marion Morel et al.   Frontiers in Genetics

Schistosomiasis in African infants and preschool children: let them now be treated!

(2013) J. Russell Stothard et al.   TRENDS IN PARASITOLOGY

The drug and vaccine landscape for neglected diseases (2000–11): a systematic assessment

(2013) Belen Pedrique et al.   Lancet Global Health

Susceptibility or resistance of praziquantel in human schistosomiasis: a review

(2012) Wei Wang et al.   PARASITOLOGY RESEARCH

Drug repositioning: Re-investigating existing drugs for new therapeutic indications

(2011) BM Padhy et al.   Journal of Postgraduate Medicine

Imatinib has a fatal impact on morphology, pairing stability and survival of adult Schistosoma mansoni in vitro

(2010) S. Beckmann et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Schistosoma mansoni Polo-like kinase 1: A mitotic kinase with key functions in parasite reproduction☆

(2010) Thavy Long et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Socioeconomic aspects of neglected tropical diseases

(2010) Lesong Conteh et al.   LANCET

Africa is desperate for praziquantel

(2010) Peter J Hotez et al.   LANCET

Piggy-backing the concept of cancer drugs for schistosomiasis treatment: a tangible perspective?

(2010) Colette Dissous et al.   TRENDS IN PARASITOLOGY

Signal transduction regulates schistosome reproductive biology

(2009) Philip T LoVerde et al.   CURRENT OPINION IN MICROBIOLOGY

Rescuing the bottom billion through control of neglected tropical diseases

(2009) Peter J Hotez et al.   LANCET

Morphological effects and tegumental alterations induced by mefloquine on schistosomula and adult flukes of Schistosoma mansoni

(2009) T. MANNECK et al.   PARASITOLOGY

In vitro and in vivo trematode models for chemotherapeutic studies

(2009) J. KEISER   PARASITOLOGY