Resveratrol Inhibits ROS-Promoted Activation and Glycolysis of Pancreatic Stellate Cells via Suppression of miR-21

Optimal dose reduction of FOLFIRINOX for preserving tumour response in advanced pancreatic cancer: Using cumulative relative dose intensity

(2017) Jong-chan Lee et al.   EUROPEAN JOURNAL OF CANCER

The role of stromal cancer-associated fibroblasts in pancreatic cancer

(2017) Dagny von Ahrens et al.   Journal of Hematology & Oncology

Safety and efficacy of FOLFIRINOX in elderly patients with metastatic or locally advanced pancreatic adenocarcinoma: A retrospective analysis

(2017) C. Baldini et al.   PANCREATOLOGY

A comprehensive review of the health perspectives of resveratrol

(2017) Abdur Rauf et al.   Food & Function

Relevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells

(2016) Oscar Peralta-Zaragoza et al.   BMC CANCER

Resveratrol inhibits Hexokinases II mediated glycolysis in non-small cell lung cancer via targeting Akt signaling pathway

(2016) Wei Li et al.   EXPERIMENTAL CELL RESEARCH

Resveratrol Inhibits Proliferation, Invasion, and Epithelial-Mesenchymal Transition by Increasing miR-200c Expression in HCT-116 Colorectal Cancer Cells

(2016) Fatemeh Karimi Dermani et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

MicroRNA-21 modulates radiation resistance through upregulation of hypoxia-inducible factor-1α-promoted glycolysis in non-small cell lung cancer cells

(2016) SHUMEI JIANG et al.   Molecular Medicine Reports

Key players in pancreatic cancer-stroma interaction: Cancer-associated fibroblasts, endothelial and inflammatory cells

(2016) Michael Friberg Bruun Nielsen et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Role of apoptosis-related miRNAs in resveratrol-induced breast cancer cell death

(2016) R Venkatadri et al.   Cell Death & Disease

Parenchymal and Stromal Cells Contribute to Pro-Inflammatory Myocardial Environment at Early Stages of Diabetes: Protective Role of Resveratrol

(2016) Monia Savi et al.   Nutrients

YAP Inhibition by Resveratrol via Activation of AMPK Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine

(2016) Zhengdong Jiang et al.   Nutrients

Anti-fibrotic effect of trans-resveratrol on pancreatic stellate cells

(2015) Siu Wai Tsang et al.   BIOMEDICINE & PHARMACOTHERAPY

Resveratrol inhibits glioma cell growth via targeting oncogenic microRNAs and multiple signaling pathways

(2015) GUANGXIU WANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Resveratrol inhibits hypoxia-driven ROS-induced invasive and migratory ability of pancreatic cancer cells via suppression of the Hedgehog signaling pathway

(2015) WEI LI et al.   ONCOLOGY REPORTS

α-Mangostin inhibits hypoxia-driven ROS-induced PSC activation and pancreatic cancer cell invasion

(2014) Jianjun Lei et al.   CANCER LETTERS

Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

(2014) L. Rahib et al.   CANCER RESEARCH

Pancreatic stellate cells and pancreas cancer: Current perspectives and future strategies

(2014) Jonathan Haqq et al.   EUROPEAN JOURNAL OF CANCER

Stromal miR-21 is more important than miR-21 of tumour cells for the progression of gastric cancer

(2014) Hiroshi Uozaki et al.   HISTOPATHOLOGY

A lentiviral sponge for miRNA-21 diminishes aerobic glycolysis in bladder cancer T24 cells via the PTEN/PI3K/AKT/mTOR axis

(2014) Xiao Yang et al.   TUMOR BIOLOGY

Connective tissue growth factor (CCN2) and microRNA-21 are components of a positive feedback loop in pancreatic stellate cells (PSC) during chronic pancreatitis and are exported in PSC-derived exosomes

(2014) Alyssa Charrier et al.   Journal of Cell Communication and Signaling

Oxidative stress plays a role in high glucose-induced activation of pancreatic stellate cells

(2013) Gyeong Ryul Ryu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Resveratrol decreases breast cancer cell viability and glucose metabolism by inhibiting 6-phosphofructo-1-kinase

(2013) Lilian S. Gomez et al.   BIOCHIMIE

Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR-21 regulation of BCL-2 expression

(2013) P. Liu et al.   Clinical & Translational Oncology

Resveratrol Inhibits the Epithelial-Mesenchymal Transition of Pancreatic Cancer Cells Via Suppression of the PI-3K/Akt/NF-κB Pathway

(2013) Wei Li et al.   CURRENT MEDICINAL CHEMISTRY

Imbalance of desmoplastic stromal cell numbers drives aggressive cancer processes

(2013) Raghu Kadaba et al.   JOURNAL OF PATHOLOGY

Targeting miR-21 for the Therapy of Pancreatic Cancer

(2013) Flavie Sicard et al.   MOLECULAR THERAPY

MicroRNA-21 in Pancreatic Ductal Adenocarcinoma Tumor-Associated Fibroblasts Promotes Metastasis

(2013) Brian E. Kadera et al.   PLoS One

Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay

(2012) T. Fiaschi et al.   CANCER RESEARCH

Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production

(2012) Claudia Capparelli et al.   CELL CYCLE

Persistent activation of pancreatic stellate cells creates a microenvironment favorable for the malignant behavior of pancreatic ductal adenocarcinoma

(2012) Dong Tang et al.   INTERNATIONAL JOURNAL OF CANCER

Resveratrol Inhibits Proliferation and Induces Apoptosis through the Hedgehog Signaling Pathway in Pancreatic Cancer Cell

(2012) Wenhui Mo et al.   PANCREATOLOGY

Resveratrol Reduces Prostate Cancer Growth and Metastasis by Inhibiting the Akt/MicroRNA-21 Pathway

(2012) Sandeep Sheth et al.   PLoS One

MicroRNAs Reprogram Normal Fibroblasts into Cancer-Associated Fibroblasts in Ovarian Cancer

(2012) A. K. Mitra et al.   Cancer Discovery

Warburg Meets Autophagy: Cancer-Associated Fibroblasts Accelerate Tumor Growth and Metastasis via Oxidative Stress, Mitophagy, and Aerobic Glycolysis

(2011) Stephanos Pavlides et al.   ANTIOXIDANTS & REDOX SIGNALING

The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

(2011) Stephanos Pavlides et al.   CELL CYCLE

Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect

(2011) Ubaldo E. Martinez-Outschoorn et al.   CELL CYCLE

mTOR upregulation of glycolytic enzymes promotes tumor development

(2011) Xiaojun Zha et al.   CELL CYCLE

Evidence for a stromal-epithelial “lactate shuttle” in human tumors

(2011) Diana Whitaker-Menezes et al.   CELL CYCLE

Resveratrol and prostate cancer: Promising role for microRNAs

(2011) Swati Dhar et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Analysis of the Human Pancreatic Stellate Cell Secreted Proteome

(2011) Angela Y. Wehr et al.   PANCREAS

Resveratrol Inhibits Growth of Orthotopic Pancreatic Tumors through Activation of FOXO Transcription Factors

(2011) Sanjit K. Roy et al.   PLoS One

Pancreatic Stellate Cells Increase the Invasion of Human Pancreatic Cancer Cells through the Stromal Cell-Derived Factor-1/CXCR4 Axis

(2010) Zhenjun Gao et al.   PANCREATOLOGY

Restoration of Altered MicroRNA Expression in the Ischemic Heart with Resveratrol

(2010) Partha Mukhopadhyay et al.   PLoS One

Roles of Pancreatic Stellate Cells in Pancreatic Inflammation and Fibrosis

(2009) Atsushi Masamune et al.   Clinical Gastroenterology and Hepatology

MicroRNA-21 protects against the H2O2-induced injury on cardiac myocytes via its target gene PDCD4

(2009) Yunhui Cheng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells

(2009) Nalinie S. Wickramasinghe et al.   NUCLEIC ACIDS RESEARCH

Antisense Inhibition of microRNA-21 or -221 Arrests Cell Cycle, Induces Apoptosis, and Sensitizes the Effects of Gemcitabine in Pancreatic Adenocarcinoma

(2009) Jong-Kook Park et al.   PANCREAS

Is Akt the “Warburg kinase”?—Akt-energy metabolism interactions and oncogenesis

(2008) R. Brooks Robey et al.   SEMINARS IN CANCER BIOLOGY