Enhanced structural diversity in terpenoid biosynthesis: enzymes, substrates and cofactors

Alternate Cyclization Cascade Initiated by Substrate Isomer in Multiproduct Terpene Synthase from Medicago truncatula

(2017) Abith Vattekkatte et al.   JOURNAL OF ORGANIC CHEMISTRY

Novel family of terpene synthases evolved fromtrans-isoprenyl diphosphate synthases in a flea beetle

(2016) Franziska Beran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolation and Characterization of Three New Monoterpene Synthases from Artemisia annua

(2016) Ju-Xin Ruan et al.   Frontiers in Plant Science

Moonlighting Metals: Insights into Regulation of Cyclization Pathways in Fungal Δ6-Protoilludene Sesquiterpene Synthases

(2015) Maureen B. Quin et al.   CHEMBIOCHEM

Isotope sensitive branching and kinetic isotope effects to analyse multiproduct terpenoid synthases from Zea mays

(2015) Nathalie Gatto et al.   CHEMICAL COMMUNICATIONS

A corpora allata farnesyl diphosphate synthase in mosquitoes displaying a metal ion dependent substrate specificity

(2015) Crisalejandra Rivera-Perez et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Substrate geometry controls the cyclization cascade in multiproduct terpene synthases from Zea mays

(2015) Abith Vattekkatte et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Inhibition of a multiproduct terpene synthase from Medicago truncatula by 3-bromoprenyl diphosphates

(2015) Abith Vattekkatte et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Germacrene A synthase in yarrow (Achillea millefolium) is an enzyme with mixed substrate specificity: gene cloning, functional characterization and expression analysis

(2015) Leila Pazouki et al.   Frontiers in Plant Science

Catalytic control in terpenoid cyclases: multiscale modeling of thermodynamic, kinetic, and dynamic effects

(2014) Dan Thomas Major et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Terpene synthases are widely distributed in bacteria

(2014) Yuuki Yamada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Detailed View of 2-Methylisoborneol Biosynthesis

(2013) Nelson L. Brock et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification of Novel Sesterterpene/Triterpene Synthase fromBacillus clausii

(2013) Tsutomu Sato et al.   CHEMBIOCHEM

Metal ions control product specificity of isoprenyl diphosphate synthases in the insect terpenoid pathway

(2013) Sindy Frick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Terpene Biosynthesis: Modularity Rules

(2011) Eric Oldfield et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sandalwood Fragrance Biosynthesis Involves Sesquiterpene Synthases of Both the Terpene Synthase (TPS)-a and TPS-b Subfamilies, including Santalene Synthases

(2011) Christopher G. Jones et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Natural sesquiterpenoids

(2011) Braulio M. Fraga   NATURAL PRODUCT REPORTS

Triterpene Cyclases fromOryza sativaL.: Cycloartenol, Parkeol and Achilleol B Synthases

(2011) Ryousuke Ito et al.   ORGANIC LETTERS

Structural Elucidation of Cisoid and Transoid Cyclization Pathways of a Sesquiterpene Synthase Using 2-Fluorofarnesyl Diphosphates

(2010) Joseph P. Noel et al.   ACS Chemical Biology

Structure of Epi-Isozizaene Synthase fromStreptomyces coelicolorA3(2), a Platform for New Terpenoid Cyclization Templates,

(2010) Julie A. Aaron et al.   BIOCHEMISTRY

Sesquiterpene Synthases Cop4 and Cop6 from Coprinus cinereus: Catalytic Promiscuity and Cyclization of Farnesyl Pyrophosphate Geometric Isomers

(2010) Fernando Lopez-Gallego et al.   CHEMBIOCHEM

A Multiproduct Terpene Synthase fromMedicago truncatulaGenerates Cadalane Sesquiterpenes via Two Different Mechanisms

(2010) Stefan Garms et al.   JOURNAL OF ORGANIC CHEMISTRY

Defining the Potassium Binding Region in an Apple Terpene Synthase

(2009) Sol Green et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diversity of sesquiterpene synthases in the basidiomyceteCoprinus cinereus

(2009) Sean Agger et al.   MOLECULAR MICROBIOLOGY

Natural sesquiterpenoids

(2009) Braulio M. Fraga   NATURAL PRODUCT REPORTS

Molecular and structural basis of metabolic diversity mediated by prenyldiphosphate converting enzymes

(2009) Wolfgang Brandt et al.   PHYTOCHEMISTRY

Monoterpene and sesquiterpene synthases and the origin of terpene skeletal diversity in plants

(2009) Jörg Degenhardt et al.   PHYTOCHEMISTRY

A Novel Pathway for Sesquiterpene Biosynthesis from Z,Z-Farnesyl Pyrophosphate in the Wild Tomato Solanum habrochaites

(2009) C. Sallaud et al.   PLANT CELL

Indirect Defense Responses to Herbivory in Grasses

(2009) J. Degenhardt   PLANT PHYSIOLOGY

Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate

(2009) A. L. Schilmiller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolation of cDNAs and functional characterisation of two multi-product terpene synthase enzymes from sandalwood, Santalum album L.

(2008) Christopher G. Jones et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Isolation and functional characterization of a β-eudesmol synthase, a new sesquiterpene synthase fromZingiber zerumbetSmith

(2008) Fengnian Yu et al.   FEBS LETTERS

Protonation of a Neutral (S)-β-Bisabolene Intermediate Is Involved in (S)-β-Macrocarpene Formation by the Maize Sesquiterpene Synthases TPS6 and TPS11

(2008) Tobias G. Köllner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Maize (E)- -Caryophyllene Synthase Implicated in Indirect Defense Responses against Herbivores Is Not Expressed in Most American Maize Varieties

(2008) T. G. Kollner et al.   PLANT CELL

Two nearly identical terpene synthases catalyze the formation of nerolidol and linalool in snapdragon flowers

(2008) Dinesh A. Nagegowda et al.   PLANT JOURNAL

Molecular and genomic basis of volatile-mediated indirect defense against insects in rice

(2008) Joshua S. Yuan et al.   PLANT JOURNAL

The molecular and biochemical basis for varietal variation in sesquiterpene content in melon (Cucumis melo L.) rinds

(2008) Vitaly Portnoy et al.   PLANT MOLECULAR BIOLOGY

Characterization of the Monoterpene Synthase Gene tps26, the Ortholog of a Gene Induced by Insect Herbivory in Maize

(2008) C. Lin et al.   PLANT PHYSIOLOGY

Biochemical and Genomic Characterization of Terpene Synthases in Magnolia grandiflora

(2008) S. Lee et al.   PLANT PHYSIOLOGY