Moonlighting Metals: Insights into Regulation of Cyclization Pathways in Fungal Δ6-Protoilludene Sesquiterpene Synthases

Evolutionary and Mechanistic Insights from the Reconstruction of α-Humulene Synthases from a Modern (+)-Germacrene A Synthase

(2014) Veronica Gonzalez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Traversing the fungal terpenome

(2014) Maureen B. Quin et al.   NATURAL PRODUCT REPORTS

Purification, crystallization and preliminary X-ray diffraction analysis of Omp6, a protoilludene synthase fromOmphalotus olearius

(2013) Maureen B. Quin et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Rational engineering of plasticity residues of sesquiterpene synthases fromArtemisia annua: product specificity and catalytic efficiency

(2013) Jian-Xu Li et al.   BIOCHEMICAL JOURNAL

Mechanistic Insights from the Binding of Substrate and Carbocation Intermediate Analogues to Aristolochene Synthase

(2013) Mengbin Chen et al.   BIOCHEMISTRY

Mushroom Hunting by Using Bioinformatics: Application of a Predictive Framework Facilitates the Selective Identification of Sesquiterpene Synthases in Basidiomycota

(2013) Maureen B. Quin et al.   CHEMBIOCHEM

Catalytic Metal Ion Rearrangements Underline Promiscuity and Evolvability of a Metalloenzyme

(2013) Moshe Ben-David et al.   JOURNAL OF MOLECULAR BIOLOGY

Natural sesquiterpenoids

(2013) Braulio M. Fraga   NATURAL PRODUCT REPORTS

Metal ions control product specificity of isoprenyl diphosphate synthases in the insect terpenoid pathway

(2013) Sindy Frick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Draft Genome of Omphalotus olearius Provides a Predictive Framework for Sesquiterpenoid Natural Product Biosynthesis in Basidiomycota

(2012) Grayson T. Wawrzyn et al.   CHEMISTRY & BIOLOGY

A 1,6-Ring Closure Mechanism for (+)-δ-Cadinene Synthase?

(2012) Juan A. Faraldos et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effect of Isotopically Sensitive Branching on Product Distribution for Pentalenene Synthase: Support for a Mechanism Predicted by Quantum Chemistry

(2012) Liansuo Zu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The specificity of herbivore-induced plant volatiles in attracting herbivore enemies

(2012) Andrea Clavijo McCormick et al.   TRENDS IN PLANT SCIENCE

Acidic calcium stores of Saccharomyces cerevisiae

(2011) Kyle W. Cunningham   CELL CALCIUM

Sesquiterpene synthases: Passive catalysts or active players?

(2011) David J. Miller et al.   NATURAL PRODUCT REPORTS

Selectivity of Fungal Sesquiterpene Synthases: Role of the Active Site's H-1  Loop in Catalysis

(2010) F. Lopez-Gallego et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Sesquiterpene Synthases Cop4 and Cop6 from Coprinus cinereus: Catalytic Promiscuity and Cyclization of Farnesyl Pyrophosphate Geometric Isomers

(2010) Fernando Lopez-Gallego et al.   CHEMBIOCHEM

Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesis

(2010) Mustafa Köksal et al.   NATURE

ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids

(2010) H. Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Crystal Structure of (+)-δ-Cadinene Synthase fromGossypium arboreumand Evolutionary Divergence of Metal Binding Motifs for Catalysis

(2009) Heather A. Gennadios et al.   BIOCHEMISTRY

Defining the Potassium Binding Region in an Apple Terpene Synthase

(2009) Sol Green et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sesquiterpene Synthase from the Botrydial Biosynthetic Gene Cluster of the PhytopathogenBotrytis cinerea

(2008) Cristina Pinedo et al.   ACS Chemical Biology

Protonation of a Neutral (S)-β-Bisabolene Intermediate Is Involved in (S)-β-Macrocarpene Formation by the Maize Sesquiterpene Synthases TPS6 and TPS11

(2008) Tobias G. Köllner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: Probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233–Mg2+B motif

(2007) L. Sangeetha Vedula et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS