FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis

SCML2 Establishes the Male Germline Epigenome through Regulation of Histone H2A Ubiquitination

(2015) Kazuteru Hasegawa et al.   DEVELOPMENTAL CELL

SLX4: Not SIMply a Nuclease Scaffold?

(2015) Ian Gibbs-Seymour et al.   MOLECULAR CELL

Polycomb Protein SCML2 Associates with USP7 and Counteracts Histone H2A Ubiquitination in the XY Chromatin during Male Meiosis

(2015) Mengcheng Luo et al.   PLoS Genetics

Crosstalk between the nucleotide excision repair and Fanconi anemia/BRCA pathways

(2014) Kent W. Mouw et al.   DNA REPAIR

BRCA1 establishes DNA damage signaling and pericentric heterochromatin of the X chromosome in male meiosis

(2014) Tyler J. Broering et al.   JOURNAL OF CELL BIOLOGY

The Genetic and Biochemical Basis of FANCD2 Monoubiquitination

(2014) Eeson Rajendra et al.   MOLECULAR CELL

Modularized Functions of the Fanconi Anemia Core Complex

(2014) Yaling Huang et al.   Cell Reports

Hypersensitivity of Primordial Germ Cells to Compromised Replication-Associated DNA Repair Involves ATM-p53-p21 Signaling

(2014) Yunhai Luo et al.   PLoS Genetics

ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing

(2013) H. Royo et al.   GENES & DEVELOPMENT

Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair

(2013) J-Y Park et al.   ONCOGENE

Properties and rates of germline mutations in humans

(2013) Catarina D. Campbell et al.   TRENDS IN GENETICS

Sex chromosome inactivation in germ cells: emerging roles of DNA damage response pathways

(2012) Yosuke Ichijima et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

RNF8 regulates active epigenetic modifications and escape gene activation from inactive sex chromosomes in post-meiotic spermatids

(2012) H.-S. Sin et al.   GENES & DEVELOPMENT

Human postmeiotic sex chromatin and its impact on sex chromosome evolution

(2012) H.-S. Sin et al.   GENOME RESEARCH

Molecular pathogenesis and clinical management of Fanconi anemia

(2012) Younghoon Kee et al.   JOURNAL OF CLINICAL INVESTIGATION

A Ubiquitin-Binding Protein, FAAP20, Links RNF8-Mediated Ubiquitination to the Fanconi Anemia DNA Repair Network

(2012) Zhijiang Yan et al.   MOLECULAR CELL

Brief Report: Human Pluripotent Stem Cell Models of Fanconi Anemia Deficiency Reveal an Important Role for Fanconi Anemia Proteins in Cellular Reprogramming and Survival of Hematopoietic Progenitors

(2012) Sun K. Yung et al.   STEM CELLS

Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells

(2011) M. Saitou et al.   DEVELOPMENT

Two distinct origins for Leydig cell progenitors in the fetal testis

(2011) Tony DeFalco et al.   DEVELOPMENTAL BIOLOGY

MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cells

(2011) Y. Ichijima et al.   GENES & DEVELOPMENT

Fancf-deficient mice are prone to develop ovarian tumours

(2011) Sietske T Bakker et al.   JOURNAL OF PATHOLOGY

Somatic mutations in aging, cancer and neurodegeneration

(2011) Scott R. Kennedy et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The phenotype of FancB-mutant mouse embryonic stem cells

(2011) Tae Moon Kim et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia

(2011) Gerry P Crossan et al.   NATURE GENETICS

Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway

(2011) K. N. Yamamoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian BTBD12 (SLX4) Protects against Genomic Instability during Mammalian Spermatogenesis

(2011) J. Kim Holloway et al.   PLoS Genetics

Targeted integration in rat and mouse embryos with zinc-finger nucleases

(2010) Xiaoxia Cui et al.   NATURE BIOTECHNOLOGY

Genome-Wide Reprogramming in the Mouse Germ Line Entails the Base Excision Repair Pathway

(2010) P. Hajkova et al.   SCIENCE

Differential Localization and Independent Acquisition of the H3K9me2 and H3K9me3 Chromatin Modifications in the Caenorhabditis elegans Adult Germ Line

(2010) Jessica B. Bessler et al.   PLoS Genetics

Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M

(2009) T. R. Singh et al.   BLOOD

Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M

(2009) Sietske T. Bakker et al.   HUMAN MOLECULAR GENETICS

FANCM Connects the Genome Instability Disorders Bloom's Syndrome and Fanconi Anemia

(2009) Andrew J. Deans et al.   MOLECULAR CELL

Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24

(2008) J. M. Kim et al.   BLOOD

Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis

(2008) Katherine Minter-Dykhouse et al.   JOURNAL OF CELL BIOLOGY