Sex chromosome inactivation in germ cells: emerging roles of DNA damage response pathways

Restricted Expression of Ovol2/MOVO in XY Body of Mouse Spermatocytes at the Pachytene Stage

(2012) R. Chizaki et al.   JOURNAL OF ANDROLOGY

Histone crotonylation specifically marks the haploid male germ cell gene expression program

(2011) Emilie Montellier et al.   BIOESSAYS

Characterization of a Novel Mouse Gene Encoding an SYCP3-Like Protein That Relocalizes from the XY Body to the Nucleolus During Prophase of Male Meiosis I1

(2011) Makiko Tsutsumi et al.   BIOLOGY OF REPRODUCTION

Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

(2011) Minjia Tan et al.   CELL

A new regulator of the cell cycle

(2011) Shumin Wu et al.   CELL CYCLE

Chromatin configuration and epigenetic landscape at the sex chromosome bivalent during equine spermatogenesis

(2011) Claudia Baumann et al.   CHROMOSOMA

Genetically enhanced asynapsis of autosomal chromatin promotes transcriptional dysregulation and meiotic failure

(2011) David Homolka et al.   CHROMOSOMA

The Y-Encoded Gene Zfy2 Acts to Remove Cells with Unpaired Chromosomes at the First Meiotic Metaphase in Male Mice

(2011) Nadège Vernet et al.   CURRENT BIOLOGY

MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cells

(2011) Y. Ichijima et al.   GENES & DEVELOPMENT

RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci

(2011) Y. Hu et al.   GENES & DEVELOPMENT

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

X-inactivation and X-reactivation: epigenetic hallmarks of mammalian reproduction and pluripotent stem cells

(2011) Bernhard Payer et al.   HUMAN GENETICS

MDC1 collaborates with TopBP1 in DNA replication checkpoint control

(2011) Jiadong Wang et al.   JOURNAL OF CELL BIOLOGY

Meiotic functions of RAD18

(2011) A. Inagaki et al.   JOURNAL OF CELL SCIENCE

ATM controls meiotic double-strand-break formation

(2011) Julian Lange et al.   NATURE

MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

(2011) Huadong Pei et al.   NATURE

Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1

(2011) Katrin Daniel et al.   NATURE CELL BIOLOGY

Sex-chromosome evolution: recent progress and the influence of male and female heterogamety

(2011) Hans Ellegren   NATURE REVIEWS GENETICS

A unique H2A histone variant occupies the transcriptional start site of active genes

(2011) Tatiana A Soboleva et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanism of RAD51-Dependent DNA Interstrand Cross-Link Repair

(2011) D. T. Long et al.   SCIENCE

Checkpoint mechanisms: the puppet masters of meiotic prophase

(2011) Amy J. MacQueen et al.   TRENDS IN CELL BIOLOGY

Function of the Sex Chromosomes in Mammalian Fertility

(2011) E. Heard et al.   Cold Spring Harbor Perspectives in Biology

Tsx Produces a Long Noncoding RNA and Has General Functions in the Germline, Stem Cells, and Brain

(2011) Montserrat C. Anguera et al.   PLoS Genetics

Mammalian BTBD12 (SLX4) Protects against Genomic Instability during Mammalian Spermatogenesis

(2011) J. Kim Holloway et al.   PLoS Genetics

ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks

(2010) Niraj M. Shanbhag et al.   CELL

MDC1: The art of keeping things in focus

(2010) Stephanie Jungmichel et al.   CHROMOSOMA

Male Meiosis: Y Keep It Silenced?

(2010) Attila Tóth et al.   CURRENT BIOLOGY

Meiotic sex chromosome inactivation

(2010) Jeffrey M. Cloutier et al.   CURRENT BIOLOGY

Evidence that Meiotic Sex Chromosome Inactivation Is Essential for Male Fertility

(2010) Hélène Royo et al.   CURRENT BIOLOGY

RNF8-Dependent Histone Modifications Regulate Nucleosome Removal during Spermatogenesis

(2010) Lin-Yu Lu et al.   DEVELOPMENTAL CELL

Sex chromosome inactivation in the male

(2010) Wei Yan et al.   Epigenetics

DNA double strand break repair, chromosome synapsis and transcriptional silencing in meiosis

(2010) Akiko Inagaki et al.   Epigenetics

Mammalian BLM helicase is critical for integrating multiple pathways of meiotic recombination

(2010) J. Kim Holloway et al.   JOURNAL OF CELL BIOLOGY

Two-Step Imprinted X Inactivation: Repeat versus Genic Silencing in the Mouse

(2010) S. H. Namekawa et al.   MOLECULAR AND CELLULAR BIOLOGY

RANBP17 is localized to the XY body of spermatocytes and interacts with SPEM1 on the manchette of elongating spermatids

(2010) Jianqiang Bao et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The FANCM/FAAP24 Complex Is Required for the DNA Interstrand Crosslink-Induced Checkpoint Response

(2010) Min Huang et al.   MOLECULAR CELL

In Brief

(2010)   NATURE REVIEWS GENETICS

UBR2 mediates transcriptional silencing during spermatogenesis via histone ubiquitination

(2010) J. Y. An et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse TRIP13/PCH2 Is Required for Recombination and Normal Higher-Order Chromosome Structure during Meiosis

(2010) Ignasi Roig et al.   PLoS Genetics

BRIT1/MCPH1 Is Essential for Mitotic and Meiotic Recombination DNA Repair and Maintaining Genomic Stability in Mice

(2010) Yulong Liang et al.   PLoS Genetics

A Global Expression Switch Marks Pachytene Initiation during Mouse Male Meiosis

(2010) Mohammad Fallahi et al.   Genes

Key Features of the X Inactivation Process Are Conserved between Marsupials and Eutherians

(2009) Shantha K. Mahadevaiah et al.   CURRENT BIOLOGY

Heterochromatin protein 1 is recruited to various types of DNA damage

(2009) Martijn S. Luijsterburg et al.   JOURNAL OF CELL BIOLOGY

Increased sex chromosome expression and epigenetic abnormalities in spermatids from male mice with Y chromosome deletions

(2009) L. N. Reynard et al.   JOURNAL OF CELL SCIENCE

BRCA1-mediated chromatin silencing is limited to oocytes with a small number of asynapsed chromosomes

(2009) A. Kouznetsova et al.   JOURNAL OF CELL SCIENCE

Single-Stranded DNA Orchestrates an ATM-to-ATR Switch at DNA Breaks

(2009) Bunsyo Shiotani et al.   MOLECULAR CELL

Many X-linked microRNAs escape meiotic sex chromosome inactivation

(2009) Rui Song et al.   NATURE GENETICS

The consequences of asynapsis for mammalian meiosis

(2009) Paul S. Burgoyne et al.   NATURE REVIEWS GENETICS

BRCA1 and its toolbox for the maintenance of genome integrity

(2009) Michael S.Y. Huen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Multicopy Gene Sly Represses the Sex Chromosomes in the Male Mouse Germline after Meiosis

(2009) Julie Cocquet et al.   PLOS BIOLOGY

Mouse HORMAD1 and HORMAD2, Two Conserved Meiotic Chromosomal Proteins, Are Depleted from Synapsed Chromosome Axes with the Help of TRIP13 AAA-ATPase

(2009) Lukasz Wojtasz et al.   PLoS Genetics

A High Incidence of Meiotic Silencing of Unsynapsed Chromatin Is Not Associated with Substantial Pachytene Loss in Heterozygous Male Mice Carrying Multiple Simple Robertsonian Translocations

(2009) Marcia Manterola et al.   PLoS Genetics

Developmental control of sumoylation pathway proteins in mouse male germ cells

(2008) Sophie La Salle et al.   DEVELOPMENTAL BIOLOGY

Drosophila PCH2 Is Required for a Pachytene Checkpoint That Monitors Double-Strand-Break-Independent Events Leading to Meiotic Crossover Formation

(2008) E. F. Joyce et al.   GENETICS

The pachytene checkpoint and its relationship to evolutionary patterns of polyploidization and hybrid sterility

(2008) X C Li et al.   HEREDITY

Extensive meiotic asynapsis in mice antagonises meiotic silencing of unsynapsed chromatin and consequently disrupts meiotic sex chromosome inactivation

(2008) Shantha K. Mahadevaiah et al.   JOURNAL OF CELL BIOLOGY

Monomethylation of Lysine 20 on Histone H4 Facilitates Chromatin Maturation

(2008) A. N. D. Scharf et al.   MOLECULAR AND CELLULAR BIOLOGY

FANCM and FAAP24 Function in ATR-Mediated Checkpoint Signaling Independently of the Fanconi Anemia Core Complex

(2008) Spencer J. Collis et al.   MOLECULAR CELL

The mouse X chromosome is enriched for multicopy testis genes showing postmeiotic expression

(2008) Jacob L Mueller et al.   NATURE GENETICS

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY