Engrailed-2(En2) deletion produces multiple neurodevelopmental defects in monoamine systems, forebrain structures and neurogenesis and behavior
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Engrailed-2(En2) deletion produces multiple neurodevelopmental defects in monoamine systems, forebrain structures and neurogenesis and behavior
Authors
Keywords
-
Journal
HUMAN MOLECULAR GENETICS
Volume 24, Issue 20, Pages 5805-5827
Publisher
Oxford University Press (OUP)
Online
2015-07-29
DOI
10.1093/hmg/ddv301
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Connectivity in Context: Emphasizing Neurodevelopment in Autism Spectrum Disorder
- (2015) James C. McPartland et al. BIOLOGICAL PSYCHIATRY
- Neurogenesis as a New Target for the Development of Antidepressant Drugs
- (2014) Jesus Pascual-Brazo et al. CURRENT PHARMACEUTICAL DESIGN
- A polygenic burden of rare disruptive mutations in schizophrenia
- (2014) Shaun M. Purcell et al. NATURE
- Serotonin 1A and Serotonin 4 Receptors
- (2014) Benjamin Adam Samuels et al. NEUROSCIENTIST
- Autism Associated Gene, ENGRAILED2, and Flanking Gene Levels Are Altered in Post-Mortem Cerebellum
- (2014) Jiyeon Choi et al. PLoS One
- Opposing Effects of α2- and β-Adrenergic Receptor Stimulation on Quiescent Neural Precursor Cell Activity and Adult Hippocampal Neurogenesis
- (2014) Dhanisha J. Jhaveri et al. PLoS One
- The effect of dopamine on adult hippocampal neurogenesis
- (2014) Naoki Takamura et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Adolescent but not adult-born neurons are critical for susceptibility to chronic social defeat
- (2014) Greer S. Kirshenbaum et al. Frontiers in Behavioral Neuroscience
- Engrailed2 modulates cerebellar granule neuron precursor proliferation, differentiation and insulin-like growth factor 1 signaling during postnatal development
- (2014) Ian T Rossman et al. Molecular Autism
- Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum
- (2014) S J James et al. Translational Psychiatry
- Brain-region–specific alterations of the trajectories of neuronal volume growth throughout the lifespan in autism
- (2014) Jerzy Wegiel et al. Acta Neuropathologica Communications
- Sex differences in autism spectrum disorders
- (2013) Donna M. Werling et al. CURRENT OPINION IN NEUROLOGY
- Neural stem cell apoptosis after low-methylmercury exposures in postnatal hippocampus produce persistent cell loss and adolescent memory deficits
- (2013) Katie Sokolowski et al. Developmental Neurobiology
- Loss of GABAergic neurons in the hippocampus and cerebral cortex of Engrailed-2 null mutant mice: Implications for autism spectrum disorders
- (2013) Paola Sgadò et al. EXPERIMENTAL NEUROLOGY
- Chronic desipramine treatment rescues depression-related, social and cognitive deficits inEngrailed-2knockout mice
- (2013) J. Brielmaier et al. GENES BRAIN AND BEHAVIOR
- A Sensitive Period for GABAergic Interneurons in the Dentate Gyrus in Modulating Sensorimotor Gating
- (2013) N. Guo et al. JOURNAL OF NEUROSCIENCE
- Functional neuroanatomy of the central noradrenergic system
- (2013) Elemer Szabadi JOURNAL OF PSYCHOPHARMACOLOGY
- Cognitive abnormalities and hippocampal alterations in monoamine oxidase A and B knockout mice
- (2013) C. Singh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Association of Posttraumatic Stress Disorder With Reduced In Vivo Norepinephrine Transporter Availability in the Locus Coeruleus
- (2013) Robert H. Pietrzak et al. JAMA Psychiatry
- Complex epigenetic regulation of Engrailed-2 (EN-2) homeobox gene in the autism cerebellum
- (2013) S J James et al. Translational Psychiatry
- Postnatal Growth Defects in Mice with Constitutive Depletion of Central Serotonin
- (2012) Nicolas Narboux-Nême et al. ACS Chemical Neuroscience
- Differences in White Matter Fiber Tract Development Present From 6 to 24 Months in Infants With Autism
- (2012) Jason J. Wolff et al. AMERICAN JOURNAL OF PSYCHIATRY
- Engrailed Is Required in Maturing Serotonin Neurons to Regulate the Cytoarchitecture and Survival of the Dorsal Raphe Nucleus
- (2012) S. R. Fox et al. JOURNAL OF NEUROSCIENCE
- Treatment of Neurodevelopmental Disorders in Adulthood
- (2012) E. Castren et al. JOURNAL OF NEUROSCIENCE
- Pten Deletion in Adult Hippocampal Neural Stem/Progenitor Cells Causes Cellular Abnormalities and Alters Neurogenesis
- (2012) A. Amiri et al. JOURNAL OF NEUROSCIENCE
- Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision
- (2012) Juan Song et al. NATURE
- Genetic architectures of psychiatric disorders: the emerging picture and its implications
- (2012) Patrick F. Sullivan et al. NATURE REVIEWS GENETICS
- Serotonin in the Modulation of Neural Plasticity and Networks: Implications for Neurodevelopmental Disorders
- (2012) Klaus-Peter Lesch et al. NEURON
- Autism-Relevant Social Abnormalities and Cognitive Deficits in Engrailed-2 Knockout Mice
- (2012) Jennifer Brielmaier et al. PLoS One
- Intermediate Phenotype Analysis of Patients, Unaffected Siblings, and Healthy Controls Identifies VMAT2 as a Candidate Gene for Psychotic Disorder and Neurocognition
- (2012) Claudia J. P. Simons et al. SCHIZOPHRENIA BULLETIN
- Depression and Hippocampal Neurogenesis: A Road to Remission?
- (2012) A. J. Eisch et al. SCIENCE
- MAOA, DBH, and SLC6A4 variants in CHARGE: a case-control study of autism spectrum disorders
- (2011) Flora Tassone et al. Autism Research
- Association study of monoamine oxidase A/B genes and schizophrenia in Han Chinese
- (2011) Yi-Liang Wei et al. Behavioral and Brain Functions
- Impairment of the tyrosine hydroxylase neuronal network in the orbitofrontal cortex of a genetically modified mouse model of schizophrenia
- (2011) Hirotaka Sekiguchi et al. BRAIN RESEARCH
- Immunohistological markers for proliferative events, gliogenesis, and neurogenesis within the adult hippocampus
- (2011) Oliver von Bohlen und Halbach CELL AND TISSUE RESEARCH
- Spatially Restricted and Developmentally Dynamic Expression of Engrailed Genes in Multiple Cerebellar Cell Types
- (2011) Sandra L. Wilson et al. CEREBELLUM
- Neurogenesis and affective disorders
- (2011) Benjamin A. Samuels et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Cut-like homeobox 1 and nuclear factor I/B mediate ENGRAILED2 autism spectrum disorder-associated haplotype function
- (2011) Jiyeon Choi et al. HUMAN MOLECULAR GENETICS
- Tbx1: identification of a 22q11.2 gene as a risk factor for autism spectrum disorder in a mouse model
- (2011) Takeshi Hiramoto et al. HUMAN MOLECULAR GENETICS
- Prenatal exposure to β2-adrenergic receptor agonists and risk of autism spectrum disorders
- (2011) Lisa A. Croen et al. Journal of Neurodevelopmental Disorders
- Affiliative Behavior Requires Juvenile, But Not Adult Neurogenesis
- (2011) L. Wei et al. JOURNAL OF NEUROSCIENCE
- Ablation of Fmrp in adult neural stem cells disrupts hippocampus-dependent learning
- (2011) Weixiang Guo et al. NATURE MEDICINE
- Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults
- (2011) Daniel Alvarez-Fischer et al. NATURE NEUROSCIENCE
- Dendritic spine pathology in neuropsychiatric disorders
- (2011) Peter Penzes et al. NATURE NEUROSCIENCE
- High Frequencies of De Novo CNVs in Bipolar Disorder and Schizophrenia
- (2011) Dheeraj Malhotra et al. NEURON
- Social Deficits and Perseverative Behaviors, but not Overt Aggression, in MAO-A Hypomorphic Mice
- (2011) Marco Bortolato et al. NEUROPSYCHOPHARMACOLOGY
- Disrupted cortical connectivity theory as an explanatory model for autism spectrum disorders
- (2011) Rajesh K. Kana et al. Physics of Life Reviews
- Noradrenaline increases neural precursor cells derived from adult rat dentate gyrus through beta2 receptor
- (2011) Takahiro Masuda et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Lateral Fluid Percussion: Model of Traumatic Brain Injury in Mice
- (2011) Janet Alder et al. Jove-Journal of Visualized Experiments
- The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes
- (2010) Jerzy Wegiel et al. ACTA NEUROPATHOLOGICA
- Histone modifications regulate the norepinephrine transporter gene
- (2010) Richard Bayles et al. CELL CYCLE
- The Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum
- (2010) Y. Cheng et al. DEVELOPMENT
- Norepinephrine and nitric oxide promote cell survival signaling in hippocampal neurons
- (2010) Neha J. Patel et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Monoamine Oxidases Regulate Telencephalic Neural Progenitors in Late Embryonic and Early Postnatal Development
- (2010) A. Cheng et al. JOURNAL OF NEUROSCIENCE
- Engrailed Homeobox Genes Regulate Establishment of the Cerebellar Afferent Circuit Map
- (2010) R. V. Sillitoe et al. JOURNAL OF NEUROSCIENCE
- Norepinephrine Directly Activates Adult Hippocampal Precursors via 3-Adrenergic Receptors
- (2010) D. J. Jhaveri et al. JOURNAL OF NEUROSCIENCE
- The age-dependent effects of selective serotonin reuptake inhibitors in humans and rodents: A review
- (2010) J.D.A. Olivier et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Drugs, Biogenic Amine Targets and the Developing Brain
- (2009) Aliya L. Frederick et al. DEVELOPMENTAL NEUROSCIENCE
- Alpha-1A adrenergic receptor activation increases inhibitory tone in CA1 hippocampus
- (2009) Kristin L. Hillman et al. EPILEPSY RESEARCH
- Pathophysiology of Locus Ceruleus Neurons in a Mouse Model of Rett Syndrome
- (2009) P. Taneja et al. JOURNAL OF NEUROSCIENCE
- Insulin-Like Growth Factor-1 Promotes G1/S Cell Cycle Progression through Bidirectional Regulation of Cyclins and Cyclin-Dependent Kinase Inhibitors via the Phosphatidylinositol 3-Kinase/Akt Pathway in Developing Rat Cerebral Cortex
- (2009) G. Mairet-Coello et al. JOURNAL OF NEUROSCIENCE
- The locus coeruleus and noradrenergic modulation of cognition
- (2009) Susan J. Sara NATURE REVIEWS NEUROSCIENCE
- Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression
- (2009) Kambiz N Alavian et al. Neural Development
- Extracellular Engrailed Participates in the Topographic Guidance of Retinal Axons In Vivo
- (2009) Andrea Wizenmann et al. NEURON
- Neurogenesis-Dependent and -Independent Effects of Fluoxetine in an Animal Model of Anxiety/Depression
- (2009) Denis J. David et al. NEURON
- Increased susceptibility to kainic acid–induced seizures in Engrailed-2 knockout mice
- (2009) P.P. Tripathi et al. NEUROSCIENCE
- Cortical enlargement in autism is associated with a functional VNTR in the monoamine oxidase A gene
- (2008) Lea K. Davis et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- The contribution of failing adult hippocampal neurogenesis to psychiatric disorders
- (2008) Gerd Kempermann et al. CURRENT OPINION IN PSYCHIATRY
- Na+/H+exchanger inhibition modifies dopamine neurotransmission during normal and metabolic stress conditions
- (2008) Marcelo A. Rocha et al. JOURNAL OF NEUROCHEMISTRY
- Adult Neurogenesis, Mental Health, and Mental Illness: Hope or Hype?
- (2008) A. J. Eisch et al. JOURNAL OF NEUROSCIENCE
- Association of the Homeobox Transcription Factor Gene ENGRAILED 2 with Autistic Disorder in Chinese Children
- (2008) Pinchen Yang et al. NEUROPSYCHOBIOLOGY
- Blocking of beta-2 adrenergic receptors hastens recovery from hypoglycemia-associated social withdrawal
- (2008) Min Jung Park et al. PSYCHONEUROENDOCRINOLOGY
- Neuroanatomy of autism
- (2008) David G. Amaral et al. TRENDS IN NEUROSCIENCES
- Association of monoamine oxidase A (MAOA) polymorphisms and clinical subgroups of major depressive disorders in the Han Chinese population
- (2008) San-Yuan Huang et al. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
- Heterogeneous association between engrailed-2 and autism in the CPEA network
- (2007) Camille W. Brune et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Association of the ENGRAILED 2 (EN2) gene with autism in Chinese Han population
- (2007) Lifang Wang et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More