SRSF10-mediated IL1RAP alternative splicing regulates cervical cancer oncogenesis via mIL1RAP-NF-κB-CD47 axis

Increased Serotonin Signaling Contributes to the Warburg Effect in Pancreatic Tumor Cells Under Metabolic Stress and Promotes Growth of Pancreatic Tumors in Mice

(2017) Shu-Heng Jiang et al.   GASTROENTEROLOGY

The role of RNA alternative splicing in regulating cancer metabolism

(2017) Itamar Kozlovski et al.   HUMAN GENETICS

RNA splicing and splicing regulator changes in prostate cancer pathology

(2017) Jennifer Munkley et al.   HUMAN GENETICS

Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors

(2017) Sharareh Gholamin et al.   Science Translational Medicine

Cervical Carcinogenesis and Immune Response Gene Polymorphisms: A Review

(2017) Akash M. Mehta et al.   Journal of Immunology Research

Molecular mechanisms of HPV mediated neoplastic progression

(2016) Rashmirani Senapati et al.   Infectious Agents and Cancer

Nuclear factor kappa B-mediated CD47 up-regulation promotes sorafenib resistance and its blockade synergizes the effect of sorafenib in hepatocellular carcinoma in mice

(2015) Jessica Lo et al.   HEPATOLOGY

IL1RAP expression as a measure of leukemic stem cell burden at diagnosis of chronic myeloid leukemia predicts therapy outcome

(2015) N Landberg et al.   LEUKEMIA

The spliceosome is a therapeutic vulnerability in MYC-driven cancer

(2015) Tiffany Y.-T. Hsu et al.   NATURE

TCGASpliceSeq a compendium of alternative mRNA splicing in cancer

(2015) Michael Ryan et al.   NUCLEIC ACIDS RESEARCH

Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia

(2015) Helena Ågerstam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer prevention and therapy through the modulation of the tumor microenvironment

(2015) Stephanie C. Casey et al.   SEMINARS IN CANCER BIOLOGY

Cytokine profile in cervical mucosa of Japanese patients with cervical intraepithelial neoplasia

(2014) Takashi Iwata et al.   International Journal of Clinical Oncology

SRSF10 Regulates Alternative Splicing and Is Required for Adipocyte Differentiation

(2014) H. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

A day in the life of the spliceosome

(2014) A. Gregory Matera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transcriptome analysis of alternative splicing events regulated by SRSF10 reveals position-dependent splicing modulation

(2014) Xuexia Zhou et al.   NUCLEIC ACIDS RESEARCH

miR-506 acts as a tumor suppressor by directly targeting the hedgehog pathway transcription factor Gli3 in human cervical cancer

(2014) S-Y Wen et al.   ONCOGENE

BCLAF1 and its splicing regulator SRSF10 regulate the tumorigenic potential of colon cancer cells

(2014) Xuexia Zhou et al.   Nature Communications

Alternative Splicing in Chronic Myeloid Leukemia (CML): A Novel Therapeutic Target?

(2013) Sophia Adamia et al.   CURRENT CANCER DRUG TARGETS

Hallmarks of alternative splicing in cancer

(2013) S Oltean et al.   ONCOGENE

Targeting the Tumor Microenvironment for Cancer Therapy

(2012) N. E. Sounni et al.   CLINICAL CHEMISTRY

Alternative splicing and evolution: diversification, exon definition and function

(2010) Hadas Keren et al.   NATURE REVIEWS GENETICS

NSSR1 is regulated by testosterone in the mouse uterus and extensively expressed in endometrial carcinoma

(2010) Zheng-Yu Peng et al.   TUMOR BIOLOGY

The nuclear signaling of NF-κB: current knowledge, new insights and future perspectives

(2009) Fengyi Wan et al.   CELL RESEARCH

Cancer-associated regulation of alternative splicing

(2009) Julian P Venables et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The biological properties of E6 and E7 oncoproteins from human papillomaviruses

(2009) Raffaella Ghittoni et al.   VIRUS GENES

NF-κB and cancer—identifying targets and mechanisms

(2008) Willscott E Naugler et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: Potential role in progression

(2008) Luigi Scotto et al.   GENES CHROMOSOMES & CANCER

Gene expression in early stage cervical cancer

(2008) Petra Biewenga et al.   GYNECOLOGIC ONCOLOGY

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

Phosphorylation switches the general splicing repressor SRp38 to a sequence-specific activator

(2008) Ying Feng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY