Molecular mechanisms of HPV mediated neoplastic progression

Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism

(2015) Zheng Hu et al.   NATURE GENETICS

Methylated Host Cell Gene Promoters and Human Papillomavirus Type 16 and 18 Predicting Cervical Lesions and Cancer

(2015) Nina Milutin Gašperov et al.   PLoS One

Virus transcript levels and cell growth rates after naturally occurring HPV16 integration events in basal cervical keratinocytes

(2014) Cinzia G Scarpini et al.   JOURNAL OF PATHOLOGY

Human Papillomavirus Type 16 E6* Induces Oxidative Stress and DNA Damage

(2014) V. M. Williams et al.   JOURNAL OF VIROLOGY

Tumourigenesis Driven by the Human Papillomavirus Type 16 Asian-American E6 Variant in a Three-Dimensional Keratinocyte Model

(2014) Robert Jackson et al.   PLoS One

Characterization of HPV and host genome interactions in primary head and neck cancers

(2014) M. Parfenov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Large Scale RNAi Reveals the Requirement of Nuclear Envelope Breakdown for Nuclear Import of Human Papillomaviruses

(2014) Inci Aydin et al.   PLoS Pathogens

Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability

(2013) K. Akagi et al.   GENOME RESEARCH

Papillomavirus E6 PDZ Interactions Can Be Replaced by Repression of p53 To Promote Episomal Human Papillomavirus Genome Maintenance

(2013) N. Brimer et al.   JOURNAL OF VIROLOGY

Landscape of genomic alterations in cervical carcinomas

(2013) Akinyemi I. Ojesina et al.   NATURE

DNA Damage Repair Genes Controlling Human Papillomavirus (HPV) Episome Levels under Conditions of Stability and Extreme Instability

(2013) Terri G. Edwards et al.   PLoS One

Human papillomavirus genome variants

(2013) Robert D. Burk et al.   VIROLOGY

Oxidative Stress and HPV Carcinogenesis

(2013) Federico De Marco   Viruses-Basel

Papillomaviruses Use Recombination-Dependent Replication to Vegetatively Amplify Their Genomes in Differentiated Cells

(2013) Nozomi Sakakibara et al.   PLoS Pathogens

Human Papillomavirus DNA Methylation as a Potential Biomarker for Cervical Cancer

(2012) M. A. Clarke et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

MicroRNA-10a targets CHL1 and promotes cell growth, migration and invasion in human cervical cancer cells

(2012) Mei-Jing Long et al.   CANCER LETTERS

Methylation of HPV18, HPV31, and HPV45 Genomes and Cervical Intraepithelial Neoplasia Grade 3

(2012) Nicolas Wentzensen et al.   JNCI-Journal of the National Cancer Institute

Engagement of the ATR-Dependent DNA Damage Response at the Human Papillomavirus 18 Replication Centers during the Initial Amplification

(2012) T. Reinson et al.   JOURNAL OF VIROLOGY

Human Papillomaviruses Recruit Cellular DNA Repair and Homologous Recombination Factors to Viral Replication Centers

(2012) K. A. Gillespie et al.   JOURNAL OF VIROLOGY

The Asian-American E6 Variant Protein of Human Papillomavirus 16 Alone Is Sufficient To Promote Immortalization, Transformation, and Migration of Primary Human Foreskin Keratinocytes

(2012) S. Niccoli et al.   JOURNAL OF VIROLOGY

Altered microRNA expression associated with chromosomal changes contributes to cervical carcinogenesis

(2012) S M Wilting et al.   ONCOGENE

Oxidative Stress in HPV-Driven Viral Carcinogenesis: Redox Proteomics Analysis of HPV-16 Dysplastic and Neoplastic Tissues

(2012) Federico De Marco et al.   PLoS One

Promoter methylation analysis of WNT/β-catenin signaling pathway regulators to detect adenocarcinoma or its precursor lesion of the cervix

(2011) W.F. van der Meide et al.   GYNECOLOGIC ONCOLOGY

Human papillomavirus (HPV) genotypes and HPV16 variants and risk of adenocarcinoma and squamous cell carcinoma of the cervix

(2011) M.L. Tornesello et al.   GYNECOLOGIC ONCOLOGY

The Papillomavirus E1 Helicase Activates a Cellular DNA Damage Response in Viral Replication Foci

(2011) N. Sakakibara et al.   JOURNAL OF VIROLOGY

Nuclear Accumulation of the Papillomavirus E1 Helicase Blocks S-Phase Progression and Triggers an ATM-Dependent DNA Damage Response

(2011) A. Fradet-Turcotte et al.   JOURNAL OF VIROLOGY

HPV16 variant lineage, clinical stage, and survival in women with invasive cervical cancer

(2011) Rosemary E Zuna et al.   Infectious Agents and Cancer

In vitro Progression of Human Papillomavirus 16 Episome-Associated Cervical Neoplasia Displays Fundamental Similarities to Integrant-Associated Carcinogenesis

(2010) E. Gray et al.   CANCER RESEARCH

A Population-Based Prospective Study of Carcinogenic Human Papillomavirus Variant Lineages, Viral Persistence, and Cervical Neoplasia

(2010) M. Schiffman et al.   CANCER RESEARCH

The role of inflammation in HPV carcinogenesis

(2010) E. Boccardo et al.   CARCINOGENESIS

Dysregulation of microRNAs in cancer: Playing with fire

(2010) Sonia A. Melo et al.   FEBS LETTERS

HPV-DNA integration and carcinogenesis: putative roles for inflammation and oxidative stress

(2010) Vonetta M Williams et al.   Future Virology

Rolling circle replication of human papillomavirus type 16 DNA in epithelial cell extracts

(2010) Rika Kusumoto-Matsuo et al.   GENES TO CELLS

MicroRNA miR-886-5p inhibits apoptosis by down-regulating Bax expression in human cervical carcinoma cells

(2010) Jing-Hua Li et al.   GYNECOLOGIC ONCOLOGY

Unique variants of human papillomavirus genotypes 52 and 58 and risk of cervical neoplasia

(2010) Ya-Ju Chang et al.   INTERNATIONAL JOURNAL OF CANCER

The clinical potential of microRNAs

(2010) Anuradha Budhu et al.   Journal of Hematology & Oncology

The immortalizing and transforming ability of two common human papillomavirus 16 E6 variants with different prevalences in cervical cancer

(2010) C Richard et al.   ONCOGENE

MicroRNA Expression Variability in Human Cervical Tissues

(2010) Patrícia M. Pereira et al.   PLoS One

Mechanisms of cell entry by human papillomaviruses: an overview

(2010) Caroline AJ Horvath et al.   Virology Journal

HPV - immune response to infection and vaccination

(2010) Margaret Stanley   Infectious Agents and Cancer

Learning from the Viral Journey: How to Enter Cells and How to Overcome Intracellular Barriers to Reach the Nucleus

(2009) Diky Mudhakir et al.   AAPS Journal

Methylation Markers for CCNA1 and C13ORF18 Are Strongly Associated with High-Grade Cervical Intraepithelial Neoplasia and Cervical Cancer in Cervical Scrapings

(2009) N. Yang et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Human Papillomavirus 16 E7 Oncoprotein Attenuates DNA Damage Checkpoint Control by Increasing the Proteolytic Turnover of Claspin

(2009) N. Spardy et al.   CANCER RESEARCH

Methylation of the long control region of HPV16 is related to the severity of cervical neoplasia

(2009) Dah-Ching Ding et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer

(2009) A. F. Fernandez et al.   GENOME RESEARCH

Assessment of DNA methylation for the detection of cervical neoplasia in liquid-based cytology specimens

(2009) Jo-Heon Kim et al.   GYNECOLOGIC ONCOLOGY

Upstream Regulatory Region Alterations Found in Human Papillomavirus Type 16 (HPV-16) Isolates from Cervical Carcinomas Increase Transcription, ori Function, and HPV Immortalization Capacity in Culture

(2009) M. J. Lace et al.   JOURNAL OF VIROLOGY

A review of human carcinogens—Part B: biological agents

(2009) Véronique Bouvard et al.   LANCET ONCOLOGY

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Epidemiology of Mucosal Human Papillomavirus Infection and Associated Diseases

(2009) Helen Trottier et al.   Public Health Genomics

Oncogenic HPV infection interrupts the expression of tumor-suppressive miR-34a through viral oncoprotein E6

(2009) X. Wang et al.   RNA

Structure, attachment and entry of polyoma- and papillomaviruses

(2009) Martin Sapp et al.   VIROLOGY

Distinct human papillomavirus type 16 methylomes in cervical cells at different stages of premalignancy

(2009) Janet L. Brandsma et al.   VIROLOGY

The molecular basis for stability of heterochromatin-mediated silencing in mammals

(2009) Kyoko Hiragami-Hamada et al.   Epigenetics & Chromatin

Establishment of Human Papillomavirus Infection Requires Cell Cycle Progression

(2009) Dohun Pyeon et al.   PLoS Pathogens

Human papillomavirus type 16 variants in cervical intraepithelial neoplasia and invasive carcinoma in San Luis Potosí City, Mexico

(2009) Rubén López-Revilla et al.   Infectious Agents and Cancer

Characterization of Naturally Occurring HPV16 Integration Sites Isolated from Cervical Keratinocytes under Noncompetitive Conditions

(2008) K. L. Dall et al.   CANCER RESEARCH

Type-Dependent Integration Frequency of Human Papillomavirus Genomes in Cervical Lesions

(2008) S. Vinokurova et al.   CANCER RESEARCH

Homologous recombination in DNA repair and DNA damage tolerance

(2008) Xuan Li et al.   CELL RESEARCH

Association between dense CADM1 promoter methylation and reduced protein expression in high-grade CIN and cervical SCC

(2008) RM Overmeer et al.   JOURNAL OF PATHOLOGY

Role of Heparan Sulfate in Attachment to and Infection of the Murine Female Genital Tract by Human Papillomavirus

(2008) K. M. Johnson et al.   JOURNAL OF VIROLOGY

Heparan Sulfate-Independent Cell Binding and Infection with Furin-Precleaved Papillomavirus Capsids

(2008) P. M. Day et al.   JOURNAL OF VIROLOGY

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

(2008) Yutaka Kondo et al.   NATURE GENETICS

Aberrant Expression of Oncogenic and Tumor-Suppressive MicroRNAs in Cervical Cancer Is Required for Cancer Cell Growth

(2008) Xiaohong Wang et al.   PLoS One

The E6E7 oncoproteins of cutaneous human papillomavirus type 38 interfere with the interferon pathway

(2008) Pablo Cordano et al.   VIROLOGY