Antibiotic resistance ABCF proteins reset the peptidyl transferase centre of the ribosome to counter translational arrest

Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus

(2017) Donna Matzov et al.   NUCLEIC ACIDS RESEARCH

Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome

(2017) Matthew J. Belousoff et al.   mBio

HPLC-based quantification of bacterial housekeeping nucleotides and alarmone messengers ppGpp and pppGpp

(2017) Vallo Varik et al.   Scientific Reports

Invited review: Architectures and mechanisms of ATP binding cassette proteins

(2016) Karl-Peter Hopfner   BIOPOLYMERS

CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database

(2016) Baofeng Jia et al.   NUCLEIC ACIDS RESEARCH

UniProt: the universal protein knowledgebase

(2016)   NUCLEIC ACIDS RESEARCH

ABC-F Proteins Mediate Antibiotic Resistance through Ribosomal Protection

(2016) Liam K. R. Sharkey et al.   mBio

The ABC of Ribosome-Related Antibiotic Resistance

(2016) Daniel N. Wilson   mBio

Lincosamides, Streptogramins, Phenicols, and Pleuromutilins: Mode of Action and Mechanisms of Resistance

(2016) Stefan Schwarz et al.   Cold Spring Harbor Perspectives in Medicine

Bacterial Protein Synthesis as a Target for Antibiotic Inhibition

(2016) Stefan Arenz et al.   Cold Spring Harbor Perspectives in Medicine

The evolutionary and functional diversity of classical and lesser-known cytoplasmic and organellar translational GTPases across the tree of life

(2015) Gemma Atkinson   BMC GENOMICS

Cryo-EM structure of the tetracycline resistance protein TetM in complex with a translating ribosome at 3.9-Å resolution

(2015) Stefan Arenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detailed Mutational Analysis of Vga(A) Interdomain Linker: Implication for Antibiotic Resistance Specificity and Mechanism

(2014) Jakub Lenart et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies

(2014) Alexandros Stamatakis   BIOINFORMATICS

Tetracycline antibiotics and resistance mechanisms

(2014) Fabian Nguyen et al.   BIOLOGICAL CHEMISTRY

The ABC-F protein EttA gates ribosome entry into the translation elongation cycle

(2014) Grégory Boël et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics

(2014) Bo Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genetic Basis forIn VitroandIn VivoResistance to Lincosamides, Streptogramins A, and Pleuromutilins (LSAP Phenotype) in Enterococcus faecium

(2013) Christophe Isnard et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Streptogramins – Two are better than one!

(2013) Yvonne Mast et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Ribosome-targeting antibiotics and mechanisms of bacterial resistance

(2013) Daniel N. Wilson   NATURE REVIEWS MICROBIOLOGY

Mechanism of tetracycline resistance by ribosomal protection protein Tet(O)

(2013) Wen Li et al.   Nature Communications

β-lactamase-mediated Resistance: A Biochemical, Epidemiological and Genetic Overview

(2012) Gabriel O. Gutkind et al.   CURRENT PHARMACEUTICAL DESIGN

Identification of novel vga(A)-carrying plasmids and a Tn5406-like transposon in meticillin-resistant Staphylococcus aureus and Staphylococcus epidermidis of human and animal origin

(2012) Carmen Lozano et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Direct binding targets of the stringent response alarmone (p)ppGpp

(2012) Usheer Kanjee et al.   MOLECULAR MICROBIOLOGY

Functional interplay between the ATP binding cassette Msr(D) protein and the membrane facilitator superfamily Mef(E) transporter for macrolide resistance in Escherichia coli

(2012) Virginia Nunez-Samudio et al.   RESEARCH IN MICROBIOLOGY

Resistance to Linezolid Caused by Modifications at Its Binding Site on the Ribosome

(2011) Katherine S. Long et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Snapshots of the maltose transporter during ATP hydrolysis

(2011) M. L. Oldham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Staphylococcus aureus SH1000 and 8325-4: comparative genome sequences of key laboratory strains in staphylococcal research

(2010) A.J. O’Neill   LETTERS IN APPLIED MICROBIOLOGY

Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action

(2010) J. A. Dunkle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Revisiting the structures of several antibiotics bound to the bacterial ribosome

(2010) D. Bulkley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A structural view on the mechanism of the ribosome-catalyzed peptide bond formation

(2009) Miljan Simonović et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:

(2009) Güliz Gürel et al.   JOURNAL OF MOLECULAR BIOLOGY

Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli

(2009) Bryson D Bennett et al.   Nature Chemical Biology

Outer membrane permeability and antibiotic resistance

(2008) Anne H. Delcour   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Hsp110 Is a Nucleotide-activated Exchange Factor for Hsp70

(2008) Claes Andréasson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure, Function, and Evolution of Bacterial ATP-Binding Cassette Systems

(2008) A. L. Davidson et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS