Integrative transcriptome sequencing reveals extensive alternative trans-splicing and cis-backsplicing in human cells

TTBK2 circular RNA promotes glioma malignancy by regulating miR-217/HNF1β/Derlin-1 pathway

(2017) Jian Zheng et al.   Journal of Hematology & Oncology

A comprehensive overview and evaluation of circular RNA detection tools

(2017) Xiangxiang Zeng et al.   PLoS Computational Biology

Evolutionary Insights into RNA trans-Splicing in Vertebrates

(2016) Quan Lei et al.   Genome Biology and Evolution

Diverse alternative back-splicing and alternative splicing landscape of circular RNAs

(2016) Xiao-Ou Zhang et al.   GENOME RESEARCH

Spliced synthetic genes as internal controls in RNA sequencing experiments

(2016) Simon A Hardwick et al.   NATURE METHODS

The biogenesis and emerging roles of circular RNAs

(2016) Ling-Ling Chen   NATURE REVIEWS MOLECULAR CELL BIOLOGY

REDIportal: a comprehensive database of A-to-I RNA editing events in humans

(2016) Ernesto Picardi et al.   NUCLEIC ACIDS RESEARCH

Circular RNA Expression: Its Potential Regulation and Function

(2016) Julia Salzman   TRENDS IN GENETICS

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

(2016) Qiupeng Zheng et al.   Nature Communications

mRNAtrans -splicing in gene therapy for genetic diseases

(2016) Adeline Berger et al.   Wiley Interdisciplinary Reviews-RNA

Circular RNAs Co-Precipitate with Extracellular Vesicles: A Possible Mechanism for circRNA Clearance

(2016) Erika Lasda et al.   PLoS One

CircRNA accumulation in the aging mouse brain

(2016) Hannah Gruner et al.   Scientific Reports

The RNA Binding Protein Quaking Regulates Formation of circRNAs

(2015) Simon J. Conn et al.   CELL

Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis

(2015) Yan Li et al.   CELL RESEARCH

Circular RNAs in Eukaryotic Cells

(2015) Liang Chen et al.   CURRENT GENOMICS

Combinatorial control ofDrosophilacircular RNA expression by intronic repeats, hnRNPs, and SR proteins

(2015) Marianne C. Kramer et al.   GENES & DEVELOPMENT

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

(2015) Agnieszka Rybak-Wolf et al.   MOLECULAR CELL

Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity

(2015) Xintian You et al.   NATURE NEUROSCIENCE

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

NCLscan: accurate identification of non-co-linear transcripts (fusion,trans-splicing and circular RNA) with a good balance between sensitivity and precision

(2015) Trees-Juen Chuang et al.   NUCLEIC ACIDS RESEARCH

Circular RNAs are long-lived and display only minimal early alterations in response to a growth factor

(2015) Yehoshua Enuka et al.   NUCLEIC ACIDS RESEARCH

Foxo3 activity promoted by non-coding effects of circular RNA and Foxo3 pseudogene in the inhibition of tumor growth and angiogenesis

(2015) W Yang et al.   ONCOGENE

Regulation of circRNA biogenesis

(2015) Ling-Ling Chen et al.   RNA Biology

The evolutionary landscape of intergenic trans-splicing events in insects

(2015) Yimeng Kong et al.   Nature Communications

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Exon Circularization Requires Canonical Splice Signals

(2015) Stefan Starke et al.   Cell Reports

Analysis of Intron Sequences Reveals Hallmarks of Circular RNA Biogenesis in Animals

(2015) Andranik Ivanov et al.   Cell Reports

Tissue-Specific Effects of Genetic and Epigenetic Variation on Gene Regulation and Splicing

(2015) Maria Gutierrez-Arcelus et al.   PLoS Genetics

Biogenesis, identification, and function of exonic circular RNAs

(2015) Iju Chen et al.   Wiley Interdisciplinary Reviews-RNA

Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development

(2015) Linda Szabo et al.   GENOME BIOLOGY

CIRI: an efficient and unbiased algorithm for de novo circular RNA identification

(2015) Yuan Gao et al.   GENOME BIOLOGY

Complementary Sequence-Mediated Exon Circularization

(2014) Xiao-Ou Zhang et al.   CELL

Short intronic repeat sequences facilitate circular RNA production

(2014) Dongming Liang et al.   GENES & DEVELOPMENT

A View of Pre-mRNA Splicing from RNase R Resistant RNAs

(2014) Hitoshi Suzuki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

circRNA Biogenesis Competes with Pre-mRNA Splicing

(2014) Reut Ashwal-Fluss et al.   MOLECULAR CELL

Detecting and characterizing circular RNAs

(2014) William R Jeck et al.   NATURE BIOTECHNOLOGY

Is an observed non-co-linear RNA product spliced intrans, incisor justin vitro?

(2014) Chun-Ying Yu et al.   NUCLEIC ACIDS RESEARCH

Circular RNA Is Expressed across the Eukaryotic Tree of Life

(2014) Peter L. Wang et al.   PLoS One

Efficient backsplicing produces translatable circular mRNAs

(2014) Yang Wang et al.   RNA

Genome-wide Analysis of Drosophila Circular RNAs Reveals Their Structural and Sequence Properties and Age-Dependent Neural Accumulation

(2014) Jakub O. Westholm et al.   Cell Reports

Integrative transcriptome sequencing identifies trans-splicing events with important roles in human embryonic stem cell pluripotency

(2013) C.-S. Wu et al.   GENOME RESEARCH

Circular Intronic Long Noncoding RNAs

(2013) Yang Zhang et al.   MOLECULAR CELL

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

RADAR: a rigorously annotated database of A-to-I RNA editing

(2013) Gokul Ramaswami et al.   NUCLEIC ACIDS RESEARCH

Cell-Type Specific Features of Circular RNA Expression

(2013) Julia Salzman et al.   PLoS Genetics

Generation of Multipotent Foregut Stem Cells from Human Pluripotent Stem Cells

(2013) Nicholas R.F. Hannan et al.   Stem Cell Reports

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Identification and analysis of pig chimeric mRNAs using RNA sequencing data

(2012) Lei Ma et al.   BMC GENOMICS

Landscape of transcription in human cells

(2012) Sarah Djebali et al.   NATURE

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Modelling and simulating generic RNA-Seq experiments with the flux simulator

(2012) Thasso Griebel et al.   NUCLEIC ACIDS RESEARCH

Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types

(2012) Julia Salzman et al.   PLoS One

Evidence for Transcript Networks Composed of Chimeric RNAs in Human Cells

(2012) Sarah Djebali et al.   PLoS One

Circular RNAs are abundant, conserved, and associated with ALU repeats

(2012) W. R. Jeck et al.   RNA

ART: a next-generation sequencing read simulator

(2011) Weichun Huang et al.   BIOINFORMATICS

A novel and well-defined benchmarking method for second generation read mapping

(2011) Manuel Holtgrewe et al.   BMC BIOINFORMATICS

Gene fusions and RNA trans-splicing in normal and neoplastic human cells

(2011) Hui Li et al.   CELL CYCLE

Locating protein-coding sequences under selection for additional, overlapping functions in 29 mammalian genomes

(2011) M. F. Lin et al.   GENOME RESEARCH

Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant

(2011) H. H. Al-Balool et al.   GENOME RESEARCH

A high-resolution map of human evolutionary constraint using 29 mammals

(2011) Kerstin Lindblad-Toh et al.   NATURE

DARNED: a DAtabase of RNa EDiting in humans

(2010) A. Kiran et al.   BIOINFORMATICS

The transcriptional interactome: gene expression in 3D

(2010) Stefan Schoenfelder et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Apparent Non-Canonical Trans-Splicing Is Generated by Reverse Transcriptase In Vitro

(2010) Jonathan Houseley et al.   PLoS One

Global analysis of trans-splicing in Drosophila

(2010) C. J. McManus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic transcriptomes during neural differentiation of human embryonic stem cells revealed by short, long, and paired-end sequencing

(2010) J. Q. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SLC45A3-ELK4 Is a Novel and Frequent Erythroblast Transformation-Specific Fusion Transcript in Prostate Cancer

(2009) D. S. Rickman et al.   CANCER RESEARCH

Implications of chimaeric non-co-linear transcripts

(2009) Thomas R. Gingeras   NATURE

ChimerDB 2.0—a knowledgebase for fusion genes updated

(2009) Pora Kim et al.   NUCLEIC ACIDS RESEARCH

The role of CTCF in regulating nuclear organization: Figure 1.

(2008) Adam Williams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7

(2008) Sylvia E. J. Fischer et al.   NATURE

A Neoplastic Gene Fusion Mimics Trans-Splicing of RNAs in Normal Human Cells

(2008) H. Li et al.   SCIENCE