TTBK2 circular RNA promotes glioma malignancy by regulating miR-217/HNF1β/Derlin-1 pathway

Circular RNAs in cancer: an emerging key player

(2017) Yeping Dong et al.   Journal of Hematology & Oncology

The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma

(2017) Giovanni Luca Gravina et al.   Journal of Hematology & Oncology

Foxo3 circular RNA promotes cardiac senescence by modulating multiple factors associated with stress and senescence responses

(2016) William W. Du et al.   EUROPEAN HEART JOURNAL

Immune phenotypes predict survival in patients with glioblastoma multiforme

(2016) Haouraa Mostafa et al.   Journal of Hematology & Oncology

CRM1/XPO1 is associated with clinical outcome in glioma and represents a therapeutic target by perturbing multiple core pathways

(2016) Xuejiao Liu et al.   Journal of Hematology & Oncology

The D Domain of LRRC4 anchors ERK1/2 in the cytoplasm and competitively inhibits MEK/ERK activation in glioma cells

(2016) Zeyou Wang et al.   Journal of Hematology & Oncology

CRNDE Promotes Malignant Progression of Glioma by Attenuating miR-384/PIWIL4/STAT3 Axis

(2016) Jian Zheng et al.   MOLECULAR THERAPY

Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2

(2016) William W. Du et al.   NUCLEIC ACIDS RESEARCH

Circular RNA Expression: Its Potential Regulation and Function

(2016) Julia Salzman   TRENDS IN GENETICS

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

(2016) Qiupeng Zheng et al.   Nature Communications

MicroRNA-217 functions as a prognosis predictor and inhibits colorectal cancer cell proliferation and invasion via an AEG-1 dependent mechanism

(2015) Bo Wang et al.   BMC CANCER

TMEM140 is associated with the prognosis of glioma by promoting cell viability and invasion

(2015) Bin Li et al.   Journal of Hematology & Oncology

Competing endogenous RNA networks: tying the essential knots for cancer biology and therapeutics

(2015) Avencia Sanchez-Mejias et al.   Journal of Hematology & Oncology

Derlin-1 is overexpressed in human colon cancer and promotes cancer cell proliferation

(2015) Xueming Tan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Encapsulated Stem Cells Loaded With Hyaluronidase-expressing Oncolytic Virus for Brain Tumor Therapy

(2015) Jordi Martinez-Quintanilla et al.   MOLECULAR THERAPY

SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance

(2015) Dohoon Kim et al.   NATURE

Circular RNAs are long-lived and display only minimal early alterations in response to a growth factor

(2015) Yehoshua Enuka et al.   NUCLEIC ACIDS RESEARCH

Circular RNA participates in the carcinogenesis and the malignant behavior of cancer

(2015) Zhen-Jun Zhao et al.   RNA Biology

Determining Associations between Human Diseases and non-coding RNAs with Critical Roles in Network Control

(2015) Haruna Kagami et al.   Scientific Reports

A review on hepatocyte nuclear factor-1beta and tumor

(2015) Dan-Dan Yu et al.   Cell and Bioscience

The MicroRNA-217 Functions as a Potential Tumor Suppressor in Gastric Cancer by Targeting GPC5

(2015) Hui Wang et al.   PLoS One

The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells

(2015) Huanyu Xu et al.   Scientific Reports

Expression of Derlin-1 and its effect on expression of autophagy marker genes under endoplasmic reticulum stress in lung cancer cells

(2014) Li Xu et al.   Cancer Cell International

Racial disparities in the association between diabetes mellitus-associated polymorphic locus rs4430796 of the HNF1βgene and prostate cancer: a systematic review and meta-analysis

(2014) Y.Z. Xiang et al.   GENETICS AND MOLECULAR RESEARCH

MiR-181a Regulates Blood-Tumor Barrier Permeability by Targeting Krüppel-Like Factor 6

(2014) Jun Ma et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Expression of Bile Duct Transcription Factor HNF1β Predicts Early Tumor Recurrence and Is a Stage-Independent Prognostic Factor in Hepatocellular Carcinoma

(2014) Ray-Hwang Yuan et al.   JOURNAL OF GASTROINTESTINAL SURGERY

MicroRNA-217 Functions as a Tumour Suppressor Gene and Correlates with Cell Resistance to Cisplatin in Lung Cancer

(2014) Junhua Guo et al.   MOLECULES AND CELLS

MicroRNA-217 Regulates WASF3 Expression and Suppresses Tumor Growth and Metastasis in Osteosarcoma

(2014) Lei Shen et al.   PLoS One

The Tau Tubulin Kinases TTBK1/2 Promote Accumulation of Pathological TDP-43

(2014) Nicole F. Liachko et al.   PLoS Genetics

Derlin-1 Is Overexpressed in Non-Small Cell Lung Cancer and Promotes Cancer Cell Invasion via EGFR-ERK–Mediated Up-Regulation of MMP-2 and MMP-9

(2013) Qian-ze Dong et al.   AMERICAN JOURNAL OF PATHOLOGY

Hepatocyte nuclear factor-1β (HNF-1β) promotes glucose uptake and glycolytic activity in ovarian clear cell carcinoma

(2013) Takako Okamoto et al.   MOLECULAR CARCINOGENESIS

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Targeting RAF-MEK-ERK kinase-scaffold interactions in cancer

(2013) Darrin D Stuart et al.   NATURE MEDICINE

Expression patterns of candidate susceptibility genes HNF1β and CtBP2 in prostate cancer: Association with tumor progression

(2013) Celine Debiais-Delpech et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Overexpression of TCL1 activates the endoplasmic reticulum stress response: a novel mechanism of leukemic progression in mice

(2012) C. L. Kriss et al.   BLOOD

The Spinocerebellar Ataxia-Associated Gene Tau Tubulin Kinase 2 Controls the Initiation of Ciliogenesis

(2012) Sarah C. Goetz et al.   CELL

A Tubulin Binding Peptide Targets Glioma Cells Disrupting Their Microtubules, Blocking Migration, and Inducing Apoptosis

(2012) Raphael Berges et al.   MOLECULAR THERAPY

PRKX, TTBK2 and RSK4 expression causes sunitinib resistance in kidney carcinoma- and melanoma-cell lines

(2011) Claus Bender et al.   INTERNATIONAL JOURNAL OF CANCER

MicroRNAs as regulators of death receptors signaling

(2009) M Garofalo et al.   CELL DEATH AND DIFFERENTIATION

Derlin-1 Is Overexpressed on the Tumor Cell Surface and Enables Antibody-Mediated Tumor Targeting Therapy

(2008) Y. Ran et al.   CLINICAL CANCER RESEARCH