The structure of an elongation factor G-ribosome complex captured in the absence of inhibitors

Scipion: A software framework toward integration, reproducibility and validation in 3D electron microscopy

(2016) J.M. de la Rosa-Trevín et al.   JOURNAL OF STRUCTURAL BIOLOGY

Elongation factor G initiates translocation through a power stroke

(2016) Chunlai Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mechanics of ribosomal translocation

(2015) John Achenbach et al.   BIOCHIMIE

Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation

(2015) Jinzhong Lin et al.   CELL

Alignment of direct detection device micrographs using a robust Optical Flow approach

(2015) Vahid Abrishami et al.   JOURNAL OF STRUCTURAL BIOLOGY

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Sampling the conformational space of the catalytic subunit of human γ-secretase

(2015) Xiao-chen Bai et al.   eLife

Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G

(2015) W. Li et al.   Science Advances

Synchronous tRNA movements during translocation on the ribosome are orchestrated by elongation factor G and GTP hydrolysis

(2014) Wolf Holtkamp et al.   BIOESSAYS

Initiation of Translation by Cricket Paralysis Virus IRES Requires Its Translocation in the Ribosome

(2014) Israel S. Fernández et al.   CELL

Following movement of domain IV of elongation factor G during ribosomal translocation

(2014) Enea Salsi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the Yeast Mitochondrial Large Ribosomal Subunit

(2014) A. Amunts et al.   SCIENCE

Trans-translation exposed: understanding the structures and functions of tmRNA-SmpB

(2014) Emmanuel Giudice et al.   Frontiers in Microbiology

Structural Basis of the Translational Elongation Cycle

(2013) Rebecca M. Voorhees et al.   Annual Review of Biochemistry

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

EF-G and EF4: translocation and back-translocation on the bacterial ribosome

(2013) Hiroshi Yamamoto et al.   NATURE REVIEWS MICROBIOLOGY

Structure of EF-G–ribosome complex in a pretranslocation state

(2013) Yun Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation

(2013) D. J. F. Ramrath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the ribosome with elongation factor G trapped in the pretranslocation state

(2013) A. F. Brilot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structures of EF-G-Ribosome Complexes Trapped in Intermediate States of Translocation

(2013) J. Zhou et al.   SCIENCE

Control of Ribosomal Subunit Rotation by Elongation Factor G

(2013) A. Pulk et al.   SCIENCE

Elongation Factor G Bound to the Ribosome in an Intermediate State of Translocation

(2013) D. S. Tourigny et al.   SCIENCE

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

(2013) Shaoxia Chen et al.   ULTRAMICROSCOPY

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Correcting pervasive errors in RNA crystallography through enumerative structure prediction

(2012) Fang-Chieh Chou et al.   NATURE METHODS

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

tmRNA–SmpB: a journey to the centre of the bacterial ribosome

(2010) Félix Weis et al.   EMBO JOURNAL

Staphylococcus aureus elongation factor G - structure and analysis of a target for fusidic acid

(2010) Yang Chen et al.   FEBS Journal

Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites

(2010) Andreas H. Ratje et al.   NATURE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Conformational changes in switch I of EF-G drive its directional cycling on and off the ribosome

(2009) Cristina Ticu et al.   EMBO JOURNAL

The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State

(2009) Y.-G. Gao et al.   SCIENCE

Precise Alignment of Peptidyl tRNA by the Decoding Center Is Essential for EF-G-Dependent Translocation

(2008) Lucia Garcia-Ortega et al.   MOLECULAR CELL