Cellular uptake mediated by epidermal growth factor receptor facilitates the intracellular activity of phosphorothioate-modified antisense oligonucleotides

The endocytic pathways of a secretory granule membrane protein in HEK293 cells: PAM and EGF traverse a dynamic multivesicular body network together

(2017) Nils Bäck et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Cellular uptake and trafficking of antisense oligonucleotides

(2017) Stanley T Crooke et al.   NATURE BIOTECHNOLOGY

Intra-endosomal trafficking mediated by lysobisphosphatidic acid contributes to intracellular release of phosphorothioate-modified antisense oligonucleotides

(2017) Shiyu Wang et al.   NUCLEIC ACIDS RESEARCH

Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides into liver hepatocytes

(2017) Michael Tanowitz et al.   NUCLEIC ACIDS RESEARCH

A subcellular map of the human proteome

(2017) Peter J. Thul et al.   SCIENCE

Hsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2′-modifications and enhances antisense activity

(2016) Xue-Hai Liang et al.   NUCLEIC ACIDS RESEARCH

Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver

(2016) Colton M. Miller et al.   NUCLEIC ACIDS RESEARCH

Development of a Quantitative BRET Affinity Assay for Nucleic Acid-Protein Interactions

(2016) Timothy A. Vickers et al.   PLoS One

NanoBRET—A Novel BRET Platform for the Analysis of Protein–Protein Interactions

(2015) Thomas Machleidt et al.   ACS Chemical Biology

Cellular uptake and intracellular trafficking of oligonucleotides

(2015) R.L. Juliano et al.   ADVANCED DRUG DELIVERY REVIEWS

Pharmacokinetics, biodistribution and cell uptake of antisense oligonucleotides

(2015) Richard S. Geary et al.   ADVANCED DRUG DELIVERY REVIEWS

Homogeneous single-label tyrosine kinase activity assay for high throughput screening

(2015) Natalia Tong-Ochoa et al.   ANALYTICA CHIMICA ACTA

Identification and characterization of intracellular proteins that bind oligonucleotides with phosphorothioate linkages

(2015) Xue-hai Liang et al.   NUCLEIC ACIDS RESEARCH

A Mass Spectrometric-Derived Cell Surface Protein Atlas

(2015) Damaris Bausch-Fluck et al.   PLoS One

Phosphorothioate oligonucleotides can displaceNEAT1RNA and form nuclear paraspeckle-like structures

(2014) Wen Shen et al.   NUCLEIC ACIDS RESEARCH

Targeted delivery of antisense oligonucleotides to hepatocytes using triantennaryN-acetyl galactosamine improves potency 10-fold in mice

(2014) Thazha P. Prakash et al.   NUCLEIC ACIDS RESEARCH

Cellular Uptake and Intracellular Trafficking of Oligonucleotides: Implications for Oligonucleotide Pharmacology

(2014) R.L. Juliano et al.   Nucleic Acid Therapeutics

Clinical pharmacokinetics of second generation antisense oligonucleotides

(2012) Rosie Z Yu et al.   Expert Opinion on Drug Metabolism & Toxicology

Receptors, endocytosis, and trafficking: the biological basis of targeted delivery of antisense and siRNA oligonucleotides

(2012) R. L. Juliano et al.   JOURNAL OF DRUG TARGETING

RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

(2010) C. Frank Bennett et al.   Annual Review of Pharmacology and Toxicology

Transfection efficiency of depolymerized chitosan and epidermal growth factor conjugated to chitosan–DNA polyplexes

(2010) Sasamon Supaprutsakul et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Intracellular delivery of an antisense oligonucleotide via endocytosis of a G protein-coupled receptor

(2010) Xin Ming et al.   NUCLEIC ACIDS RESEARCH

Dendrimer-triglycine-EGF nanoparticles for tumor imaging and targeted nucleic acid and drug delivery

(2010) Quan Yuan et al.   ORAL ONCOLOGY

Intracellular delivery of an anionic antisense oligonucleotide via receptor-mediated endocytosis

(2008) Md Rowshon Alam et al.   NUCLEIC ACIDS RESEARCH