Generalized Anxiety Disorder (GAD) and Comorbid Major Depression with GAD Are Characterized by Enhanced Nitro-oxidative Stress, Increased Lipid Peroxidation, and Lowered Lipid-Associated Antioxidant Defenses

Uric acid in major depressive and anxiety disorders

(2018) Catherine N. Black et al.   JOURNAL OF AFFECTIVE DISORDERS

In major affective disorders, early life trauma predict increased nitro-oxidative stress, lipid peroxidation and protein oxidation and recurrence of major affective disorders, suicidal behaviors and a lowered quality of life

(2018) Juliana Brum Moraes et al.   METABOLIC BRAIN DISEASE

The Compensatory Immune-Regulatory Reflex System (CIRS) in Depression and Bipolar Disorder

(2018) Michael Maes et al.   MOLECULAR NEUROBIOLOGY

Are there differences in lipid peroxidation and immune biomarkers between major depression and bipolar disorder: Effects of melancholia, atypical depression, severity of illness, episode number, suicidal ideation and prior suicide attempts

(2018) Magdalena Sowa-Kućma et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Natural regulatory IgM-mediated autoimmune responses directed against malondialdehyde regulate oxidative and nitrosative pathways and coupled with IgM responses to nitroso adducts attenuate depressive and physiosomatic symptoms at the end of term pregnanc

(2018) Chutima Roomruangwong et al.   PSYCHIATRY AND CLINICAL NEUROSCIENCES

Cytokines in systemic lupus erythematosus: far beyond Th1/Th2 dualism lupus: cytokine profiles

(2017) Poliana Macedo Guimarães et al.   IMMUNOLOGY AND CELL BIOLOGY

Activated neuro-oxidative and neuro-nitrosative pathways at the end of term are associated with inflammation and physio-somatic and depression symptoms, while predicting outcome characteristics in mother and baby

(2017) Chutima Roomruangwong et al.   JOURNAL OF AFFECTIVE DISORDERS

Increased Root Canal Endotoxin Levels are Associated with Chronic Apical Periodontitis, Increased Oxidative and Nitrosative Stress, Major Depression, Severity of Depression, and a Lowered Quality of Life

(2017) Cinthya Gomes et al.   MOLECULAR NEUROBIOLOGY

Lipid Peroxidation and Immune Biomarkers Are Associated with Major Depression and Its Phenotypes, Including Treatment-Resistant Depression and Melancholia

(2017) Magdalena Sowa-Kućma et al.   NEUROTOXICITY RESEARCH

Shared metabolic and immune-inflammatory, oxidative and nitrosative stress pathways in the metabolic syndrome and mood disorders

(2017) Luiz Gustavo Piccoli de Melo et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Lowered PON1 activities are strongly associated with depression and bipolar disorder, recurrence of (hypo)mania and depression, increased disability and lowered quality of life

(2017) Estefania Gastaldello Moreira et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Key Developments in Translational Neuroscience: an Update

(2017) Drozdstoy St. Stoyanov   Balkan Medical Journal

Anxiety disorders

(2017) Michelle G. Craske et al.   Nature Reviews Disease Primers

Comorbid Anxiety Disorders in Canadians with Bipolar Disorder: Clinical Characteristics and Service Use

(2017) Lisa D Hawke et al.   CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE

Comorbid generalized anxiety disorder and its association with quality of life in patients with major depressive disorder

(2017) Yongjie Zhou et al.   Scientific Reports

Superoxide Ion: Generation and Chemical Implications

(2016) Maan Hayyan et al.   CHEMICAL REVIEWS

Uric acid levels in subjects with bipolar disorder: A comparative meta-analysis

(2016) Francesco Bartoli et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Nitrosative Stress, Hypernitrosylation, and Autoimmune Responses to Nitrosylated Proteins: New Pathways in Neuroprogressive Disorders Including Depression and Chronic Fatigue Syndrome

(2016) Gerwyn Morris et al.   MOLECULAR NEUROBIOLOGY

Inflammation in Fear- and Anxiety-Based Disorders: PTSD, GAD and Beyond

(2016) Vasiliki Michopoulos et al.   NEUROPSYCHOPHARMACOLOGY

Paraoxonase 1 (PON1) Q192R genotypes and their interaction with smoking strongly increase atherogenicity and the Framingham risk score

(2016) Andre de Souza-Nogueira et al.   Archives of Endocrinology Metabolism

Primary Care Management of Patients with Co-occurring Disorders

(2016) Larry Culpepper   CNS SPECTRUMS

The impact of maternal smoking during pregnancy on depressive and anxiety behaviors in children: the Norwegian Mother and Child Cohort Study

(2015) Steven Moylan et al.   BMC Medicine

Pretreatment with curcumin attenuates anxiety while strengthens memory performance after one short stress experience in male rats

(2015) Saida Haider et al.   BRAIN RESEARCH BULLETIN

Paraoxonase 1 and HDL maturation

(2015) Alejandro Gugliucci et al.   CLINICA CHIMICA ACTA

Human paraoxonase-1 (PON1): Gene structure and expression, promiscuous activities and multiple physiological roles

(2015) Mike Mackness et al.   GENE

Atherogenic index of plasma and atherogenic coefficient are increased in major depression and bipolar disorder, especially when comorbid with tobacco use disorder

(2015) Sandra Odebrecht Vargas Nunes et al.   JOURNAL OF AFFECTIVE DISORDERS

Anxiety sensitivity and trait anxiety are associated with response to 7.5% carbon dioxide challenge

(2015) Meg E Fluharty et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Evaluation of oxidative and antioxidative parameters in generalized anxiety disorder

(2015) Ali Emhan et al.   PSYCHIATRY RESEARCH

A Lifetime Prevalence of Comorbidity Between Bipolar Affective Disorder and Anxiety Disorders: A Meta-analysis of 52 Interview-based Studies of Psychiatric Population

(2015) Behrouz Nabavi et al.   EBioMedicine

A Meta-Analysis of Oxidative Stress Markers in Depression

(2015) Tao Liu et al.   PLoS One

Association of Oxidative Stress to the Genesis of Anxiety: Implications for Possible Therapeutic Interventions

(2014) Waseem Hassan et al.   Current Neuropharmacology

Lowered plasma paraoxonase (PON)1 activity is a trait marker of major depression and PON1 Q192R gene polymorphism–smoking interactions differentially predict the odds of major depression and bipolar disorder

(2014) Chiara Cristina Bortolasci et al.   JOURNAL OF AFFECTIVE DISORDERS

Oxidative & nitrosative stress in depression: Why so much stress?

(2014) Steven Moylan et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The Effect of Agoraphobia on Oxidative Stress in Panic Disorder

(2014) Isil Gogcegoz Gul et al.   Psychiatry Investigation

An updated meta-analysis of oxidative stress markers in bipolar disorder

(2014) Nicole C. Brown et al.   PSYCHIATRY RESEARCH

Paraoxonase (PON)1 Q192R functional genotypes and PON1 Q192R genotype by smoking interactions are risk factors for the metabolic syndrome, but not overweight or obesity

(2014) Chiara Cristina Bortolasci et al.   REDOX REPORT

T cell activation induces CuZn superoxide dismutase (SOD)-1 intracellular re-localization, production and secretion

(2013) Giuseppe Terrazzano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Potential Role of Uric Acid in Metabolic Syndrome, Hypertension, Kidney Injury, and Cardiovascular Diseases: Is It Time for Reappraisal?

(2013) Zohreh Soltani et al.   CURRENT HYPERTENSION REPORTS

Reduced PON1 enzymatic activity and increased lipid hydroperoxide levels that point out oxidative stress in generalized anxiety disorder

(2013) Mahmut Bulut et al.   JOURNAL OF AFFECTIVE DISORDERS

Effects of cigarette smoking on HDL quantity and function: Implications for atherosclerosis

(2013) Bai-mei He et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex

(2013) Ying Huang et al.   JOURNAL OF CLINICAL INVESTIGATION

The shared role of oxidative stress and inflammation in major depressive disorder and nicotine dependence

(2013) Sandra Odebrecht Vargas Nunes et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Exercising the worry away: How inflammation, oxidative and nitrogen stress mediates the beneficial effect of physical activity on anxiety disorder symptoms and behaviours

(2013) S. Moylan et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Decreased Serum Sulphydryl Levels as a Sign of Increased Oxidative Stress in Generalized Anxiety Disorder

(2013) Mehmet Cemal Kaya et al.   Psychiatry Investigation

Quantitation of malondialdehyde in gingival crevicular fluid by a high-performance liquid chromatography-based method

(2012) Alliny Souza Bastos et al.   ANALYTICAL BIOCHEMISTRY

Improved detection of advanced oxidation protein products in plasma

(2012) Marita Hanasand et al.   CLINICA CHIMICA ACTA

The expression of genes encoding for COX-2, MPO, iNOS, and sPLA2-IIA in patients with recurrent depressive disorder

(2012) Piotr Gałecki et al.   JOURNAL OF AFFECTIVE DISORDERS

Superoxide Dismutases: Role in Redox Signaling, Vascular Function, and Diseases

(2011) Tohru Fukai et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidative stress and hematological profiles of advanced breast cancer patients subjected to paclitaxel or doxorubicin chemotherapy

(2011) C. Panis et al.   BREAST CANCER RESEARCH AND TREATMENT

Serum uric acid levels and the clinical characteristics of depression

(2011) Shenglin Wen et al.   CLINICAL BIOCHEMISTRY

Pitfalls in the assessment of PON1 status in clinical populations

(2011) Scott S. Billecke et al.   FERTILITY AND STERILITY

IgM-mediated autoimmune responses directed against multiple neoepitopes in depression: New pathways that underpin the inflammatory and neuroprogressive pathophysiology

(2011) Michael Maes et al.   JOURNAL OF AFFECTIVE DISORDERS

Deficiency of CuZn Superoxide Dismutase Promotes Inflammation and Alters Medial Structure Following Vascular Injury

(2011) Norio Ishigami et al.   Journal of Atherosclerosis and Thrombosis

Effect of cigarette smoking on paraoxonase 1 activity according to PON1 L55M and PON1 Q192R gene polymorphisms

(2011) Dhouha Haj Mouhamed et al.   Environmental Health and Preventive Medicine

Human myeloperoxidase in innate and acquired immunity

(2010) Juergen Arnhold et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Scared to Death? Generalized Anxiety Disorder and Cardiovascular Events in Patients With Stable Coronary Heart Disease

(2010) Elisabeth J. Martens et al.   ARCHIVES OF GENERAL PSYCHIATRY

Increased plasma peroxides and serum oxidized low density lipoprotein antibodies in major depression: Markers that further explain the higher incidence of neurodegeneration and coronary artery disease

(2010) Michael Maes et al.   JOURNAL OF AFFECTIVE DISORDERS

Multiple aberrations in shared inflammatory and oxidative & nitrosative stress (IO&NS) pathways explain the co-association of depression and cardiovascular disorder (CVD), and the increased risk for CVD and due mortality in depressed patients

(2010) Michael Maes et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness

(2010) Michael Maes et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Toward New Approaches to Psychotic Disorders: The NIMH Research Domain Criteria Project

(2010) B. N. Cuthbert et al.   SCHIZOPHRENIA BULLETIN

Generalized Anxiety Disorder Is Associated with Metabolic Syndrome in the Vietnam Experience Study

(2009) Douglas Carroll et al.   BIOLOGICAL PSYCHIATRY

Regulation of superoxide dismutase genes: Implications in disease

(2009) Lu Miao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactions of Peroxynitrite with Uric Acid: Formation of Reactive Intermediates, Alkylated Products and Triuret, and In Vivo Production of Triuret Under Conditions of Oxidative Stress

(2009) Christine Gersch et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Evidence that oxidative stress is linked to anxiety-related behaviour in mice

(2008) Hassan Rammal et al.   BRAIN BEHAVIOR AND IMMUNITY

Is generalized anxiety disorder an anxiety or mood disorder? Considering multiple factors as we ponder the fate of GAD

(2008) Douglas S. Mennin et al.   DEPRESSION AND ANXIETY

The nosologic relationship between generalized anxiety disorder and major depression

(2008) John M. Hettema   DEPRESSION AND ANXIETY

Oxidative stress markers in bipolar disorder: A meta-analysis

(2008) Ana C. Andreazza et al.   JOURNAL OF AFFECTIVE DISORDERS

Uric Acid: The Oxidant-Antioxidant Paradox

(2008) Yuri Y. Sautin et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Paraoxonase 1 (PON1) status and substrate hydrolysis

(2008) Rebecca J. Richter et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY