Potassium Channel Gain of Function in Epilepsy: An Unresolved Paradox

Diversity of astrocyte potassium channels: An update

(2018) Gerald Seifert et al.   BRAIN RESEARCH BULLETIN

Regulation of Eag by Ca2+/calmodulin controls presynaptic excitability in Drosophila

(2018) Peter Bronk et al.   JOURNAL OF NEUROPHYSIOLOGY

Gliotransmission: Beyond Black-and-White

(2018) Iaroslav Savtchouk et al.   JOURNAL OF NEUROSCIENCE

Multiple Lines of Evidence Indicate That Gliotransmission Does Not Occur under Physiological Conditions

(2018) Todd A. Fiacco et al.   JOURNAL OF NEUROSCIENCE

Neonatal nonepileptic myoclonus is a prominent clinical feature of KCNQ2 gain-of-function variants R201C and R201H

(2017) Sarah B. Mulkey et al.   EPILEPSIA

Structural insights into the mechanisms of CNBD channel function

(2017) Zachary M. James et al.   JOURNAL OF GENERAL PHYSIOLOGY

Threading the biophysics of mammalian Slo1 channels onto structures of an invertebrate Slo1 channel

(2017) Yu Zhou et al.   JOURNAL OF GENERAL PHYSIOLOGY

The chemical basis for electrical signaling

(2017) William A Catterall et al.   Nature Chemical Biology

The role of axonal Kv1 channels in CA3 pyramidal cell excitability

(2017) Sylvain Rama et al.   Scientific Reports

Modulation of Kv7 channels and excitability in the brain

(2016) Derek L. Greene et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Infantile spasms and encephalopathy without preceding neonatal seizures caused byKCNQ2R198Q, a gain-of-function variant

(2016) John J. Millichap et al.   EPILEPSIA

Multiplex families with epilepsy

(2016) Zaid Afawi et al.   NEUROLOGY

A Novel Form of Local Plasticity in Tuft Dendrites of Neocortical Somatosensory Layer 5 Pyramidal Neurons

(2016) Maya Sandler et al.   NEURON

Potassium Channels and Human Epileptic Phenotypes: An Updated Overview

(2016) Chiara Villa et al.   Frontiers in Cellular Neuroscience

Potassium Channels in Epilepsy

(2016) Rüdiger Köhling et al.   Cold Spring Harbor Perspectives in Medicine

Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy

(2016) Federico Sicca et al.   Scientific Reports

A novel epileptic encephalopathy mutation inKCNB1disrupts Kv2.1 ion selectivity, expression, and localization

(2015) Isabelle Thiffault et al.   JOURNAL OF GENERAL PHYSIOLOGY

Early-Onset Epileptic Encephalopathy Caused by Gain-of-Function Mutations in the Voltage Sensor of Kv7.2 and Kv7.3 Potassium Channel Subunits

(2015) F. Miceli et al.   JOURNAL OF NEUROSCIENCE

De novo loss- or gain-of-function mutations in KCNA2 cause epileptic encephalopathy

(2015) Steffen Syrbe et al.   NATURE GENETICS

Subcellular Localization of K+ Channels in Mammalian Brain Neurons: Remarkable Precision in the Midst of Extraordinary Complexity

(2015) James S. Trimmer   NEURON

KCNQ5 K+ channels control hippocampal synaptic inhibition and fast network oscillations

(2015) Pawel Fidzinski et al.   Nature Communications

The Neuroglial Potassium Cycle during Neurotransmission: Role of Kir4.1 Channels

(2015) Jérémie Sibille et al.   PLoS Computational Biology

De novoKCNB1mutations in epileptic encephalopathy

(2014) Ali Torkamani et al.   ANNALS OF NEUROLOGY

The chandelier cell, form and function

(2014) Melis Inan et al.   CURRENT OPINION IN NEUROBIOLOGY

Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability

(2014) D. J. Speca et al.   GENES BRAIN AND BEHAVIOR

KV10.1 opposes activity-dependent increase in Ca2+influx into the presynaptic terminal of the parallel fibre-Purkinje cell synapse

(2014) Lena Sünke Mortensen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Exome sequencing reveals new causal mutations in children with epileptic encephalopathies

(2013) Krishna R. Veeramah et al.   EPILEPSIA

Kv2 channels regulate firing rate in pyramidal neurons from rat sensorimotor cortex

(2013) Dongxu Guan et al.   JOURNAL OF PHYSIOLOGY-LONDON

Enhanced Intrinsic Excitability in Basket Cells Maintains Excitatory-Inhibitory Balance in Hippocampal Circuits

(2013) Emilie Campanac et al.   NEURON

An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations

(2012) Ernesto Vargas et al.   JOURNAL OF GENERAL PHYSIOLOGY

Missense mutations in the sodium-gated potassium channel gene KCNT1 cause severe autosomal dominant nocturnal frontal lobe epilepsy

(2012) Sarah E Heron et al.   NATURE GENETICS

De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy

(2012) Giulia Barcia et al.   NATURE GENETICS

What are the mechanisms for analogue and digital signalling in the brain?

(2012) Dominique Debanne et al.   NATURE REVIEWS NEUROSCIENCE

Genetic activation of BK currents in vivo generates bidirectional effects on neuronal excitability

(2012) J. R. Montgomery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMIGO is an auxiliary subunit of the Kv2.1 potassium channel

(2011) Marjaana A Peltola et al.   EMBO REPORTS

Respiratory alkalosis in children with febrile seizures

(2011) Sebastian Schuchmann et al.   EPILEPSIA

State-Dependent Function of Neocortical Chandelier Cells

(2011) A. R. Woodruff et al.   JOURNAL OF NEUROSCIENCE

Autism with Seizures and Intellectual Disability: Possible Causative Role of Gain-of-function of the Inwardly-Rectifying K+ Channel Kir4.1

(2011) Federico Sicca et al.   NEUROBIOLOGY OF DISEASE

Axon Physiology

(2011) Dominique Debanne et al.   PHYSIOLOGICAL REVIEWS

Homeostatic Synaptic Plasticity: Local and Global Mechanisms for Stabilizing Neuronal Function

(2011) G. Turrigiano   Cold Spring Harbor Perspectives in Biology

Spike-Time Precision and Network Synchrony Are Controlled by the Homeostatic Regulation of the D-Type Potassium Current

(2010) R. H. Cudmore et al.   JOURNAL OF NEUROSCIENCE

An Epilepsy/Dyskinesia-Associated Mutation Enhances BK Channel Activation by Potentiating Ca2+ Sensing

(2010) Junqiu Yang et al.   NEURON

Neural KCNQ (Kv7) channels

(2009) David A Brown et al.   BRITISH JOURNAL OF PHARMACOLOGY

NAD+ Activates KNa Channels in Dorsal Root Ganglion Neurons

(2009) T. J. Tamsett et al.   JOURNAL OF NEUROSCIENCE

Ternary Kv4.2 channels recapitulate voltage-dependent inactivation kinetics of A-type K+channels in cerebellar granule neurons

(2008) Yimy Amarillo et al.   JOURNAL OF PHYSIOLOGY-LONDON

Altered synaptic and non-synaptic properties of CA1 pyramidal neurons in Kv4.2 knockout mice

(2008) B. K. Andrásfalvy et al.   JOURNAL OF PHYSIOLOGY-LONDON

Localization and Targeting of Voltage-Dependent Ion Channels in Mammalian Central Neurons

(2008) Helene Vacher et al.   PHYSIOLOGICAL REVIEWS