Axon Physiology

Presynaptic action potential waveform determines cortical synaptic latency

(2011) Sami Boudkkazi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Neurological Channelopathies

(2010) Dimitri M. Kullmann   Annual Review of Neuroscience

Building and maintaining the axon initial segment

(2010) Matthew S Grubb et al.   CURRENT OPINION IN NEUROBIOLOGY

P/Q and N Channels Control Baseline and Spike-Triggered Calcium Levels in Neocortical Axons and Synaptic Boutons

(2010) Y. Yu et al.   JOURNAL OF NEUROSCIENCE

The Sushi Domains of GABAB Receptors Function as Axonal Targeting Signals

(2010) B. Biermann et al.   JOURNAL OF NEUROSCIENCE

Conduction Block in PMP22 Deficiency

(2010) Y. Bai et al.   JOURNAL OF NEUROSCIENCE

Presynaptic Resurgent Na+ Currents Sculpt the Action Potential Waveform and Increase Firing Reliability at a CNS Nerve Terminal

(2010) J. Hee Kim et al.   JOURNAL OF NEUROSCIENCE

ADAM22, A Kv1 Channel-Interacting Protein, Recruits Membrane-Associated Guanylate Kinases to Juxtaparanodes of Myelinated Axons

(2010) Y. Ogawa et al.   JOURNAL OF NEUROSCIENCE

Spike-Time Precision and Network Synchrony Are Controlled by the Homeostatic Regulation of the D-Type Potassium Current

(2010) R. H. Cudmore et al.   JOURNAL OF NEUROSCIENCE

Action Potentials Initiate in the Axon Initial Segment and Propagate through Axon Collaterals Reliably in Cerebellar Purkinje Neurons

(2010) A. Foust et al.   JOURNAL OF NEUROSCIENCE

Insights into migraine mechanisms and CaV2.1 calcium channel function from mouse models of familial hemiplegic migraine

(2010) Daniela Pietrobon   JOURNAL OF PHYSIOLOGY-LONDON

Axon initial segment dysfunction in epilepsy

(2010) Verena C. Wimmer et al.   JOURNAL OF PHYSIOLOGY-LONDON

Pain channelopathies

(2010) Roman Cregg et al.   JOURNAL OF PHYSIOLOGY-LONDON

RAPID REPORT: Initiation of simple and complex spikes in cerebellar Purkinje cells

(2010) Lucy M. Palmer et al.   JOURNAL OF PHYSIOLOGY-LONDON

Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability

(2010) Matthew S. Grubb et al.   NATURE

Presynaptic activity regulates Na+ channel distribution at the axon initial segment

(2010) Hiroshi Kuba et al.   NATURE

Presynaptic GABAA receptors enhance transmission and LTP induction at hippocampal mossy fiber synapses

(2010) Arnaud Ruiz et al.   NATURE NEUROSCIENCE

Ca2+-dependent enhancement of release by subthreshold somatic depolarization

(2010) Jason M Christie et al.   NATURE NEUROSCIENCE

Na+ imaging reveals little difference in action potential–evoked Na+ influx between axon and soma

(2010) Ilya A Fleidervish et al.   NATURE NEUROSCIENCE

Slow integration leads to persistent action potential firing in distal axons of coupled interneurons

(2010) Mark E J Sheffield et al.   NATURE NEUROSCIENCE

Myelination and the trophic support of long axons

(2010) Klaus-Armin Nave   NATURE REVIEWS NEUROSCIENCE

EphA4 Signaling in Juveniles Establishes Topographic Specificity of Structural Plasticity in the Hippocampus

(2010) Ivan Galimberti et al.   NEURON

Presynaptic Miniature Gabaergic Currents in Developing Interneurons

(2010) Federico F. Trigo et al.   NEURON

Unraveling Mechanisms of Homeostatic Synaptic Plasticity

(2010) Karine Pozo et al.   NEURON

Dopaminergic Modulation of Axon Initial Segment Calcium Channels Regulates Action Potential Initiation

(2010) Kevin J. Bender et al.   NEURON

Bursts and hyperexcitability in non-myelinated axons of the rat hippocampus

(2010) D. Palani et al.   NEUROSCIENCE

Functional reciprocity between Na+ channel Nav1.6 and  1 subunits in the coordinated regulation of excitability and neurite outgrowth

(2010) W. J. Brackenbury et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Identity of Dendritic Voltage-Gated Sodium Channels

(2010) A. Lorincz et al.   SCIENCE

Impact of Spikelets on Hippocampal CA1 Pyramidal Cell Activity During Spatial Exploration

(2010) J. Epsztein et al.   SCIENCE

Three-Dimensional, Flexible Nanoscale Field-Effect Transistors as Localized Bioprobes

(2010) B. Tian et al.   SCIENCE

Nonsynaptic Communication Through ATP Release from Volume-Activated Anion Channels in Axons

(2010) R. D. Fields et al.   Science Signaling

Retrograde axonal transport: pathways to cell death?

(2010) Eran Perlson et al.   TRENDS IN NEUROSCIENCES

Neocortical Axon Arbors Trade-off Material and Conduction Delay Conservation

(2010) Julian M. L. Budd et al.   PLoS Computational Biology

Establishment of Axon-Dendrite Polarity in Developing Neurons

(2009) Anthony P. Barnes et al.   Annual Review of Neuroscience

A Gate Keeper for Axonal Transport

(2009) Shaohua Xiao et al.   CELL

A Selective Filter for Cytoplasmic Transport at the Axon Initial Segment

(2009) Ai-hong Song et al.   CELL

Nerve conduction and excitability studies in peripheral nerve disorders

(2009) Christian Krarup et al.   CURRENT OPINION IN NEUROLOGY

Conduction block and glial injury induced in developing central white matter by glycine, GABA, noradrenalin, or nicotine, studied in isolated neonatal rat optic nerve

(2009) Stavros Constantinou et al.   GLIA

Subcellular compartment-specific molecular diversity of pre- and post-synaptic GABAB-activated GIRK channels in Purkinje cells

(2009) Laura Fernández-Alacid et al.   JOURNAL OF NEUROCHEMISTRY

Cell-Type-Dependent Molecular Composition of the Axon Initial Segment

(2009) A. Lorincz et al.   JOURNAL OF NEUROSCIENCE

Complex Intrinsic Membrane Properties and Dopamine Shape Spiking Activity in a Motor Axon

(2009) A. W. Ballo et al.   JOURNAL OF NEUROSCIENCE

Disruption of the Axon Initial Segment Cytoskeleton Is a New Mechanism for Neuronal Injury

(2009) D. P. Schafer et al.   JOURNAL OF NEUROSCIENCE

Submillisecond Optical Reporting of Membrane Potential In Situ Using a Neuronal Tracer Dye

(2009) J. Bradley et al.   JOURNAL OF NEUROSCIENCE

Selective Expression of Ligand-Gated Ion Channels in L5 Pyramidal Cell Axons

(2009) J. M. Christie et al.   JOURNAL OF NEUROSCIENCE

Mice with Altered Myelin Proteolipid Protein Gene Expression Display Cognitive Deficits Accompanied by Abnormal Neuron-Glia Interactions and Decreased Conduction Velocities

(2009) H. Tanaka et al.   JOURNAL OF NEUROSCIENCE

Small voltage changes at nerve terminals travel up axons to affect action potential initiation

(2009) Kenneth Paradiso et al.   NATURE NEUROSCIENCE

Who let the spikes out?

(2009) Chris G Dulla et al.   NATURE NEUROSCIENCE

Distinct contributions of Nav1.6 and Nav1.2 in action potential initiation and backpropagation

(2009) Wenqin Hu et al.   NATURE NEUROSCIENCE

Tubulin tyrosination navigates the kinesin-1 motor domain to axons

(2009) Yoshiyuki Konishi et al.   NATURE NEUROSCIENCE

Head-anchored whole-cell recordings in freely moving rats

(2009) Albert K Lee et al.   Nature Protocols

Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window

(2009) Anthony Holtmaat et al.   Nature Protocols

Experience-dependent structural synaptic plasticity in the mammalian brain

(2009) Anthony Holtmaat et al.   NATURE REVIEWS NEUROSCIENCE

Encoding of Oscillations by Axonal Bursts in Inferior Olive Neurons

(2009) Alexandre Mathy et al.   NEURON

Wnt Signaling Mediates Experience-Related Regulation of Synapse Numbers and Mossy Fiber Connectivities in the Adult Hippocampus

(2009) Nadine Gogolla et al.   NEURON

Axon Initial Segment Ca2+ Channels Influence Action Potential Generation and Timing

(2009) Kevin J. Bender et al.   NEURON

Electrogenic Tuning of the Axon Initial Segment

(2009) Brian D. Clark et al.   NEUROSCIENTIST

Experience-Driven Axon Retraction in the Pharmacologically Inactivated Visual Cortex Does Not Require Synaptic Transmission

(2009) Kana Watanabe et al.   PLoS One

Presynaptic NR2A-containing NMDA receptors implement a high-pass filter synaptic plasticity rule

(2009) C. Bidoret et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Energy-Efficient Action Potentials in Hippocampal Mossy Fibers

(2009) H. Alle et al.   SCIENCE

Actin and Microtubule-Based Cytoskeletal Cues Direct Polarized Targeting of Proteins in Neurons

(2009) D. B. Arnold   Science Signaling

Variability in the subcellular distribution of ion channels increases neuronal diversity

(2009) Zoltan Nusser   TRENDS IN NEUROSCIENCES

Axon-Glial Signaling and the Glial Support of Axon Function

(2008) Klaus-Armin Nave et al.   Annual Review of Neuroscience

Role of Axonal Transport in Neurodegenerative Diseases

(2008) Kurt J. De Vos et al.   Annual Review of Neuroscience

Multiple Sclerosis: An Immune or Neurodegenerative Disorder?

(2008) Bruce D. Trapp et al.   Annual Review of Neuroscience

Activity-dependent regulation of myelin maintenance in the adult rat

(2008) Marie-Hélène Canu et al.   BRAIN RESEARCH

Plasticity of Polarization: Changing Dendrites into Axons in Neurons Integrated in Neuronal Circuits

(2008) Susana Gomis-Rüth et al.   CURRENT BIOLOGY

Analog signalling in mammalian cortical axons

(2008) Henrik Alle et al.   CURRENT OPINION IN NEUROBIOLOGY

The functional organization and assembly of the axon initial segment

(2008) Yasuhiro Ogawa et al.   CURRENT OPINION IN NEUROBIOLOGY

Role of hippocampal sodium channel Nav1.6 in kindling epileptogenesis

(2008) Hal Blumenfeld et al.   EPILEPSIA

Model of very fast (> 75 Hz) network oscillations generated by electrical coupling between the proximal axons of cerebellar Purkinje cells

(2008) Roger D. Traub et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Axonal GABAAreceptors

(2008) Federico F. Trigo et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The H-current secures action potential transmission at high frequencies in rat cerebellar parallel fibers

(2008) Armantas Baginskas et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity

(2008) Kristian L. Hedstrom et al.   JOURNAL OF CELL BIOLOGY

Protein kinase CK2 contributes to the organization of sodium channels in axonal membranes by regulating their interactions with ankyrin G

(2008) Aline Bréchet et al.   JOURNAL OF CELL BIOLOGY

Tight junctions potentiate the insulative properties of small CNS myelinated axons

(2008) Jerome Devaux et al.   JOURNAL OF CELL BIOLOGY

Inhibition of the ATP-gated P2X7 receptor promotes axonal growth and branching in cultured hippocampal neurons

(2008) M. Diaz-Hernandez et al.   JOURNAL OF CELL SCIENCE

Pre-synaptic GABABreceptors inhibit glutamate release through GIRK channels in rat cerebral cortex

(2008) Carolina Ladera et al.   JOURNAL OF NEUROCHEMISTRY

Role of Axonal NaV1.6 Sodium Channels in Action Potential Initiation of CA1 Pyramidal Neurons

(2008) Michel Royeck et al.   JOURNAL OF NEUROPHYSIOLOGY

High Threshold, Proximal Initiation, and Slow Conduction Velocity of Action Potentials in Dentate Granule Neuron Mossy Fibers

(2008) Geraldine J. Kress et al.   JOURNAL OF NEUROPHYSIOLOGY

Self-Limited Hyperexcitability: Functional Effect of a Familial Hemiplegic Migraine Mutation of the Nav1.1 (SCN1A) Na+ Channel

(2008) S. Cestele et al.   JOURNAL OF NEUROSCIENCE

Analog Modulation of Mossy Fiber Transmission Is Uncoupled from Changes in Presynaptic Ca2+

(2008) R. Scott et al.   JOURNAL OF NEUROSCIENCE

GABAergic Depolarization of the Axon Initial Segment in Cortical Principal Neurons Is Caused by the Na-K-2Cl Cotransporter NKCC1

(2008) S. Khirug et al.   JOURNAL OF NEUROSCIENCE

Downregulation of Dendritic Ih in CA1 Pyramidal Neurons after LTP

(2008) E. Campanac et al.   JOURNAL OF NEUROSCIENCE

Cortical Action Potential Backpropagation Explains Spike Threshold Variability and Rapid-Onset Kinetics

(2008) Y. Yu et al.   JOURNAL OF NEUROSCIENCE

Multiple Molecular Interactions Determine the Clustering of Caspr2 and Kv1 Channels in Myelinated Axons

(2008) I. Horresh et al.   JOURNAL OF NEUROSCIENCE

Functional Trade-Offs in White Matter Axonal Scaling

(2008) S. S.-H. Wang et al.   JOURNAL OF NEUROSCIENCE

Postsynaptic Density-93 Clusters Kv1 Channels at Axon Initial Segments Independently of Caspr2

(2008) Y. Ogawa et al.   JOURNAL OF NEUROSCIENCE

Autonomous initiation and propagation of action potentials in neurons of the subthalamic nucleus

(2008) Jeremy F. Atherton et al.   JOURNAL OF PHYSIOLOGY-LONDON

Electrophysiological events recorded at presynaptic terminals of the crayfish neuromuscular junction with a voltage indicator

(2008) Jen-Wei Lin   JOURNAL OF PHYSIOLOGY-LONDON

Action potential initiation and propagation in hippocampal mossy fibre axons

(2008) Christoph Schmidt-Hieber et al.   JOURNAL OF PHYSIOLOGY-LONDON

Initial segment Kv2.2 channels mediate a slow delayed rectifier and maintain high frequency action potential firing in medial nucleus of the trapezoid body neurons

(2008) Jamie Johnston et al.   JOURNAL OF PHYSIOLOGY-LONDON

Roles of axonal sodium channels in precise auditory time coding at nucleus magnocellularis of the chick

(2008) Hiroshi Kuba et al.   JOURNAL OF PHYSIOLOGY-LONDON

New role of IKKα/β phosphorylated IκBα in axon outgrowth and axon initial segment development

(2008) Diana Sanchez-Ponce et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Nav1.1 is predominantly expressed in nodes of Ranvier and axon initial segments

(2008) Amandine Duflocq et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Is action potential threshold lowest in the axon?

(2008) Maarten H P Kole et al.   NATURE NEUROSCIENCE

Action potential generation requires a high sodium channel density in the axon initial segment

(2008) Maarten H P Kole et al.   NATURE NEUROSCIENCE

Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis

(2008) Lindsey L Glickfeld et al.   NATURE NEUROSCIENCE

Paired-recordings from synaptically coupled cortical and hippocampal neurons in acute and cultured brain slices

(2008) Dominique Debanne et al.   Nature Protocols

Purinergic signalling and disorders of the central nervous system

(2008) Geoffrey Burnstock   NATURE REVIEWS DRUG DISCOVERY

Presynaptic glutamate receptors: physiological functions and mechanisms of action

(2008) Paulo S. Pinheiro et al.   NATURE REVIEWS NEUROSCIENCE

Plasticity of intrinsic neuronal properties in CNS disorders

(2008) Heinz Beck et al.   NATURE REVIEWS NEUROSCIENCE

Control of Presynaptic Function by a Persistent Na+ Current

(2008) Hai Huang et al.   NEURON

Dendritic NMDA Receptors Activate Axonal Calcium Channels

(2008) Jason M. Christie et al.   NEURON

LTD Induction Causes Morphological Changes of Presynaptic Boutons and Reduces Their Contacts with Spines

(2008) Nadine Becker et al.   NEURON

K+ Channels at the Axon Initial Segment Dampen Near-Threshold Excitability of Neocortical Fast-Spiking GABAergic Interneurons

(2008) Ethan M. Goldberg et al.   NEURON

High-Frequency Network Oscillations in Cerebellar Cortex

(2008) Steven J. Middleton et al.   NEURON

Retigabine reduces the excitability of unmyelinated peripheral human axons

(2008) P LANG et al.   NEUROPHARMACOLOGY

Action potential initiation and propagation: Upstream influences on neurotransmission

(2008) G.J. Kress et al.   NEUROSCIENCE

Oligodendrocytes Changing the Rules: Action Potentials in Glia and Oligodendrocytes Controlling Action Potentials

(2008) R. Douglas Fields   NEUROSCIENTIST

Local Gene Expression in Axons and Nerve Endings: The Glia-Neuron Unit

(2008) Antonio Giuditta et al.   PHYSIOLOGICAL REVIEWS

Localization and Targeting of Voltage-Dependent Ion Channels in Mammalian Central Neurons

(2008) Helene Vacher et al.   PHYSIOLOGICAL REVIEWS

Intracellular Transport and Kinesin Superfamily Proteins, KIFs: Structure, Function, and Dynamics

(2008) Nobutaka Hirokawa et al.   PHYSIOLOGICAL REVIEWS

Dendritic Excitability and Synaptic Plasticity

(2008) P. Jesper Sjöström et al.   PHYSIOLOGICAL REVIEWS

Long-Term Activity-Dependent Plasticity of Action Potential Propagation Delay and Amplitude in Cortical Networks

(2008) Douglas J. Bakkum et al.   PLoS One

Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons

(2008) M. M. Shah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spike timing-dependent plasticity: a learning rule for dendritic integration in rat CA1 pyramidal neurons

(2007) Emilie Campanac et al.   JOURNAL OF PHYSIOLOGY-LONDON