Mass cytometry analysis of immune cells in the brain

Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency

(2017) Yannick Simoni et al.   IMMUNITY

High-dimensional, single-cell characterization of the brain's immune compartment

(2017) Ben Korin et al.   NATURE NEUROSCIENCE

Mapping the human DC lineage through the integration of high-dimensional techniques

(2017) Peter See et al.   SCIENCE

Single-Cell RNA Sequencing: Unraveling the Brain One Cell at a Time

(2017) Dimitry Ofengeim et al.   TRENDS IN MOLECULAR MEDICINE

Rapid monoisotopic cisplatin based barcoding for multiplexed mass cytometry

(2017) Ryan L. McCarthy et al.   Scientific Reports

Modulation of neuronal excitability by immune mediators in epilepsy

(2016) Valentina Iori et al.   CURRENT OPINION IN PHARMACOLOGY

Cluster stability in the analysis of mass cytometry data

(2016) Rossella Melchiotti et al.   CYTOMETRY PART A

Cell size assays for mass cytometry

(2016) Alan D. Stern et al.   CYTOMETRY PART A

Comparison of clustering methods for high-dimensional single-cell flow and mass cytometry data

(2016) Lukas M. Weber et al.   CYTOMETRY PART A

Social defeat induces depressive-like states and microglial activation without involvement of peripheral macrophages

(2016) Michael L. Lehmann et al.   Journal of Neuroinflammation

Phenotypic and functional characterization of a bortezomib-resistant multiple myeloma cell line by flow and mass cytometry

(2016) Linda B. Baughn et al.   LEUKEMIA & LYMPHOMA

Wishbone identifies bifurcating developmental trajectories from single-cell data

(2016) Manu Setty et al.   NATURE BIOTECHNOLOGY

Mass cytometry: blessed with the curse of dimensionality

(2016) Evan W Newell et al.   NATURE IMMUNOLOGY

PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease

(2016) Kuti Baruch et al.   NATURE MEDICINE

Automated mapping of phenotype space with single-cell data

(2016) Nikolay Samusik et al.   NATURE METHODS

Microglial brain region−dependent diversity and selective regional sensitivities to aging

(2016) Kathleen Grabert et al.   NATURE NEUROSCIENCE

Visualization and cellular hierarchy inference of single-cell data using SPADE

(2016) Benedict Anchang et al.   Nature Protocols

In Situ Transcription Profiling of Single Cells Reveals Spatial Organization of Cells in the Mouse Hippocampus

(2016) Sheel Shah et al.   NEURON

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microglia development follows a stepwise program to regulate brain homeostasis

(2016) O. Matcovitch-Natan et al.   SCIENCE

Meningeal Tertiary Lymphoid Tissues and Multiple Sclerosis: A Gathering Place for Diverse Types of Immune Cells during CNS Autoimmunity

(2016) Natalia B. Pikor et al.   Frontiers in Immunology

A CD45-based barcoding approach to multiplex mass-cytometry (CyTOF)

(2015) Liyun Lai et al.   CYTOMETRY PART A

FlowSOM: Using self-organizing maps for visualization and interpretation of cytometry data

(2015) Sofie Van Gassen et al.   CYTOMETRY PART A

The end of gating? An introduction to automated analysis of high dimensional cytometry data

(2015) Florian Mair et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm

(2015) Eli R Zunder et al.   Nature Protocols

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

Neuroinflammation: Ways in Which the Immune System Affects the Brain

(2015) Richard M. Ransohoff et al.   Neurotherapeutics

Spatially resolved, highly multiplexed RNA profiling in single cells

(2015) K. H. Chen et al.   SCIENCE

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

(2015) A. Zeisel et al.   SCIENCE

Microglia: Dynamic Mediators of Synapse Development and Plasticity

(2015) Yuwen Wu et al.   TRENDS IN IMMUNOLOGY

Breaking immune tolerance by targeting Foxp3+ regulatory T cells mitigates Alzheimer’s disease pathology

(2015) Kuti Baruch et al.   Nature Communications

High yield extraction of pure spinal motor neurons, astrocytes and microglia from single embryo and adult mouse spinal cord

(2015) Marie-Josée Beaudet et al.   Scientific Reports

Migration of Bone Marrow-Derived Cells Into the Central Nervous System in Models of Neurodegeneration

(2015) Antoine Lampron et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Large-Scale and Comprehensive Immune Profiling and Functional Analysis of Normal Human Aging

(2015) Chan C. Whiting et al.   PLoS One

Single-Cell Trajectory Detection Uncovers Progression and Regulatory Coordination in Human B Cell Development

(2014) Sean C. Bendall et al.   CELL

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

High-dimensional analysis of the murine myeloid cell system

(2014) Burkhard Becher et al.   NATURE IMMUNOLOGY

Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry

(2014) Charlotte Giesen et al.   NATURE METHODS

Intravascular staining for discrimination of vascular and tissue leukocytes

(2014) Kristin G Anderson et al.   Nature Protocols

Automated identification of stratifying signatures in cellular subpopulations

(2014) Robert V. Bruggner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes

(2014) J. N. H. Stern et al.   Science Translational Medicine

Single-molecule fluorescence in situ hybridization: Quantitative imaging of single RNA molecules

(2013) Sunjong Kwon   BMB Reports

Normalization of mass cytometry data with bead standards

(2013) Rachel Finck et al.   CYTOMETRY PART A

viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia

(2013) El-ad David Amir et al.   NATURE BIOTECHNOLOGY

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

Hyperactively restricting angiogenesis

(2013) Darran Yates   NATURE REVIEWS NEUROSCIENCE

Dissociated Neurons and Glial Cells Derived from Rat Inferior Colliculi after Digestion with Papain

(2013) Odett Kaiser et al.   PLoS One

Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue

(2013) M. J. Gerdes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammation and Adaptive Immunity in Parkinson's Disease

(2013) R. L. Mosley et al.   Cold Spring Harbor Perspectives in Medicine

A platinum-based covalent viability reagent for single-cell mass cytometry

(2012) Harris G. Fienberg et al.   CYTOMETRY PART A

Histo-Cytometry: A Method for Highly Multiplex Quantitative Tissue Imaging Analysis Applied to Dendritic Cell Subset Microanatomy in Lymph Nodes

(2012) Michael Y. Gerner et al.   IMMUNITY

Efficient isolation of live microglia with preserved phenotypes from adult mouse brain

(2012) Maria Nikodemova et al.   Journal of Neuroinflammation

Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators

(2012) Bernd Bodenmiller et al.   NATURE BIOTECHNOLOGY

A deep profiler's guide to cytometry

(2012) Sean C. Bendall et al.   TRENDS IN IMMUNOLOGY

Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE

(2011) Peng Qiu et al.   NATURE BIOTECHNOLOGY

CyTOF—the next generation of cell detection

(2011) Regina K. Cheung et al.   Nature Reviews Rheumatology

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Highly multiparametric analysis by mass cytometry

(2010) Olga Ornatsky et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function

(2010) eMalick G. Njie et al.   NEUROBIOLOGY OF AGING

Study of Cell Antigens and Intracellular DNA by Identification of Element-Containing Labels and Metallointercalators Using Inductively Coupled Plasma Mass Spectrometry

(2008) O. I. Ornatsky et al.   ANALYTICAL CHEMISTRY