A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease

Genetic variants in Alzheimer disease — molecular and brain network approaches

(2016) Chris Gaiteri et al.   Nature Reviews Neurology

Relation of genomic variants for Alzheimer disease dementia to common neuropathologies

(2016) Jose M. Farfel et al.   NEUROLOGY

Bayesian Network Reconstruction Using Systems Genetics Data: Comparison of MCMC Methods

(2015) Shinya Tasaki et al.   GENETICS

Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders

(2015) Neelroop N. Parikshak et al.   NATURE REVIEWS GENETICS

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Identifying robust communities and multi-community nodes by combining top-down and bottom-up approaches to clustering

(2015) Chris Gaiteri et al.   Scientific Reports

A Genome-wide Gene-Expression Analysis and Database in Transgenic Mice during Development of Amyloid or Tau Pathology

(2015) Mar Matarin et al.   Cell Reports

Bayesian Network Reconstruction Using Systems Genetics Data: Comparison of MCMC Methods

(2015) Shinya Tasaki et al.   GENETICS

CGG repeats in RNA modulate expression of TDP-43 in mouse and fly models of fragile X tremor ataxia syndrome

(2014) Jocelyn N. Galloway et al.   HUMAN MOLECULAR GENETICS

Cell-Type-Specific Repression by Methyl-CpG-Binding Protein 2 Is Biased toward Long Genes

(2014) K. Sugino et al.   JOURNAL OF NEUROSCIENCE

Age-specific population frequencies of cerebral β-amyloidosis and neurodegeneration among people with normal cognitive function aged 50–89 years: a cross-sectional study

(2014) Clifford R Jack et al.   LANCET NEUROLOGY

G9a influences neuronal subtype specification in striatum

(2014) Ian Maze et al.   NATURE NEUROSCIENCE

Molecular adaptations of striatal spiny projection neurons during levodopa-induced dyskinesia

(2014) M. Heiman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

(2014) Jeffrey L Cummings et al.   Alzheimers Research & Therapy

Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias

(2014) Gary W. Beecham et al.   PLoS Genetics

Much of late life cognitive decline is not due to common neurodegenerative pathologies

(2013) Patricia A. Boyle et al.   ANNALS OF NEUROLOGY

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

(2013) Bin Zhang et al.   CELL

Overview and Findings from the Religious Orders Study

(2013) David A. Bennett et al.   Current Alzheimer Research

Overview and Findings from the Rush Memory and Aging Project

(2013) David A. Bennett et al.   Current Alzheimer Research

Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation

(2013) J. Dalal et al.   GENES & DEVELOPMENT

Beyond modules and hubs: the potential of gene coexpression networks for investigating molecular mechanisms of complex brain disorders

(2013) C. Gaiteri et al.   GENES BRAIN AND BEHAVIOR

Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals

(2013) A. Battle et al.   GENOME RESEARCH

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Comparative analysis of RNA sequencing methods for degraded or low-input samples

(2013) Xian Adiconis et al.   NATURE METHODS

Integrative approaches for finding modular structure in biological networks

(2013) Koyel Mitra et al.   NATURE REVIEWS GENETICS

Disentangling the effects of age and APOE on neuropathology and late life cognitive decline

(2013) Lei Yu et al.   NEUROBIOLOGY OF AGING

Alzheimer disease in the United States (2010-2050) estimated using the 2010 census

(2013) L. E. Hebert et al.   NEUROLOGY

Normalizing RNA-Sequencing Data by Modeling Hidden Covariates with Prior Knowledge

(2013) Sara Mostafavi et al.   PLoS One

MicroRNA-128 Governs Neuronal Excitability and Motor Behavior in Mice

(2013) C. L. Tan et al.   SCIENCE

Relation of neuropathology to cognition in persons without cognitive impairment

(2012) David A. Bennett et al.   ANNALS OF NEUROLOGY

INRICH: interval-based enrichment analysis for genome-wide association studies

(2012) Phil H. Lee et al.   BIOINFORMATICS

Cognitive impairment, decline and fluctuations in older community-dwelling subjects with Lewy bodies

(2012) J. A. Schneider et al.   BRAIN

Identification of the Cortical Neurons that Mediate Antidepressant Responses

(2012) Eric F. Schmidt et al.   CELL

Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

(2012) Konrad Talbot et al.   JOURNAL OF CLINICAL INVESTIGATION

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Identifying ChIP-seq enrichment using MACS

(2012) Jianxing Feng et al.   Nature Protocols

Developmental Coordination of Gene Expression between Synaptic Partners During GABAergic Circuit Assembly in Cerebellar Cortex

(2012) Anirban Paul et al.   Frontiers in Neural Circuits

Patterns of Cis Regulatory Variation in Diverse Human Populations

(2012) Barbara E. Stranger et al.   PLoS Genetics

Increased Expression of Axogenesis-Related Genes and Mossy Fibre Length in Dentate Granule Cells from Adult HuD Overexpressor Mice

(2011) Nora I Perrone-Bizzozero et al.   ASN Neuro

More than nervous: The emerging roles of plexins

(2011) Nina Perälä et al.   DIFFERENTIATION

A genome-wide scan for common variants affecting the rate of age-related cognitive decline

(2011) Philip L. De Jager et al.   NEUROBIOLOGY OF AGING

Recruited Cells Can Become Transformed and Overtake PDGF-Induced Murine Gliomas In Vivo during Tumor Progression

(2011) Elena I. Fomchenko et al.   PLoS One

Is My Network Module Preserved and Reproducible?

(2011) Peter Langfelder et al.   PLoS Computational Biology

CR1is associated with amyloid plaque burden and age-related cognitive decline

(2010) Lori B. Chibnik et al.   ANNALS OF NEUROLOGY

VTA neurons show a potentially protective transcriptional response to MPTP

(2010) Sudarshan Phani et al.   BRAIN RESEARCH

In Vivo Fate Mapping and Expression Analysis Reveals Molecular Hallmarks of Prospectively Isolated Adult Neural Stem Cells

(2010) Ruth Beckervordersandforth et al.   Cell Stem Cell

SHIP2 and its involvement in various diseases

(2010) Akira Suwa et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The Inositol Phosphatase SHIP2 Negatively Regulates Insulin/IGF-I Actions Implicated in Neuroprotection and Memory Function in Mouse Brain

(2010) Yoshiyuki Soeda et al.   MOLECULAR ENDOCRINOLOGY

Comprehensive comparative analysis of strand-specific RNA sequencing methods

(2010) Joshua Z Levin et al.   NATURE METHODS

A Bayesian Framework to Account for Complex Non-Genetic Factors in Gene Expression Levels Greatly Increases Power in eQTL Studies

(2010) Oliver Stegle et al.   PLoS Computational Biology

The neuropathology of probable Alzheimer disease and mild cognitive impairment

(2009) Julie A. Schneider et al.   ANNALS OF NEUROLOGY

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Transcriptional and Electrophysiological Maturation of Neocortical Fast-Spiking GABAergic Interneurons

(2009) B. W. Okaty et al.   JOURNAL OF NEUROSCIENCE

Neuroscience in the era of functional genomics and systems biology

(2009) Daniel H. Geschwind et al.   NATURE

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types

(2008) Joseph P. Doyle et al.   CELL

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

Improving the structure MCMC sampler for Bayesian networks by introducing a new edge reversal move

(2008) Marco Grzegorczyk et al.   MACHINE LEARNING